PubMed

Increased in vivo regeneration of cortisol in adipose tissue in human obesity and effects of the 11beta-hydroxysteroid dehydrogenase type 1 inhibitor carbenoxolone.

Sandeep TC, Andrew R, Homer NZ, Andrews RC, Smith K, Walker BR.

Diabetes. 2005 Mar;54(3):872-9.PMID: 15734867 [PubMed - indexed for MEDLINE]Related articlesFree article

Body fat distribution and cortisol metabolism in healthy men: enhanced 5beta-reductase and lower cortisol/cortisone metabolite ratios in men with fatty liver.

Westerbacka J, Yki-Järvinen H, Vehkavaara S, Häkkinen AM, Andrew R, Wake DJ, Seckl JR, Walker BR.

J Clin Endocrinol Metab. 2003 Oct;88(10):4924-31.PMID: 14557475 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute in vivo regulation of 11beta-hydroxysteroid dehydrogenase type 1 activity by insulin and intralipid infusions in humans.

Wake DJ, Homer NZ, Andrew R, Walker BR.

J Clin Endocrinol Metab. 2006 Nov;91(11):4682-8. Epub 2006 Sep 5.PMID: 16954164 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of peroxisome proliferator-activated receptor-alpha and -gamma agonists on 11beta-hydroxysteroid dehydrogenase type 1 in subcutaneous adipose tissue in men.

Wake DJ, Stimson RH, Tan GD, Homer NZ, Andrew R, Karpe F, Walker BR.

J Clin Endocrinol Metab. 2007 May;92(5):1848-56. Epub 2007 Feb 27.PMID: 17327378 [PubMed - indexed for MEDLINE]Related articlesFree article

Local and systemic impact of transcriptional up-regulation of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue in human obesity.

Wake DJ, Rask E, Livingstone DE, Söderberg S, Olsson T, Walker BR.

J Clin Endocrinol Metab. 2003 Aug;88(8):3983-8.PMID: 12915696 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes.

Andrews RC, Rooyackers O, Walker BR.

J Clin Endocrinol Metab. 2003 Jan;88(1):285-91.PMID: 12519867 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue-specific dysregulation of cortisol metabolism in human obesity.

Rask E, Olsson T, Söderberg S, Andrew R, Livingstone DE, Johnson O, Walker BR.

J Clin Endocrinol Metab. 2001 Mar;86(3):1418-21.PMID: 11238541 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue production of cortisol by 11beta-hydroxysteroid dehydrogenase type 1 and metabolic disease.

Walker BR, Andrew R.

Ann N Y Acad Sci. 2006 Nov;1083:165-84. Review.PMID: 17148739 [PubMed - indexed for MEDLINE]Related articles

Is 11beta-hydroxysteroid dehydrogenase type 1 a therapeutic target? Effects of carbenoxolone in lean and obese Zucker rats.

Livingstone DE, Walker BR.

J Pharmacol Exp Ther. 2003 Apr;305(1):167-72.PMID: 12649365 [PubMed - indexed for MEDLINE]Related articlesFree article

11 beta-hydroxysteroid dehydrogenase type 1 in obesity and the metabolic syndrome.

Wake DJ, Walker BR.

Mol Cell Endocrinol. 2004 Feb 27;215(1-2):45-54. Review.PMID: 15026174 [PubMed - indexed for MEDLINE]Related articles

Cortisol release from adipose tissue by 11beta-hydroxysteroid dehydrogenase type 1 in humans.

Stimson RH, Andersson J, Andrew R, Redhead DN, Karpe F, Hayes PC, Olsson T, Walker BR.

Diabetes. 2009 Jan;58(1):46-53. Epub 2008 Oct 13.PMID: 18852329 [PubMed - indexed for MEDLINE]Related articlesFree article

The contribution of visceral adipose tissue to splanchnic cortisol production in healthy humans.

Andrew R, Westerbacka J, Wahren J, Yki-Järvinen H, Walker BR.

Diabetes. 2005 May;54(5):1364-70.PMID: 15855321 [PubMed - indexed for MEDLINE]Related articlesFree article

11beta-Hydroxysteroid dehydrogenase type 1-driven cortisone reactivation regulates plasminogen activator inhibitor type 1 in adipose tissue of obese women.

Ayachi SE, Paulmyer-Lacroix O, Verdier M, Alessi MC, Dutour A, Grino M.

J Thromb Haemost. 2006 Mar;4(3):621-7.PMID: 16460444 [PubMed - indexed for MEDLINE]Related articles

11beta-hydroxysteroid dehydrogenase type 1 and obesity.

Morton NM, Seckl JR.

Front Horm Res. 2008;36:146-64. Review.PMID: 18230901 [PubMed - indexed for MEDLINE]Related articles

Dietary macronutrient content alters cortisol metabolism independently of body weight changes in obese men.

Stimson RH, Johnstone AM, Homer NZ, Wake DJ, Morton NM, Andrew R, Lobley GE, Walker BR.

J Clin Endocrinol Metab. 2007 Nov;92(11):4480-4. Epub 2007 Sep 4.PMID: 17785367 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue-specific changes in peripheral cortisol metabolism in obese women: increased adipose 11beta-hydroxysteroid dehydrogenase type 1 activity.

Rask E, Walker BR, Söderberg S, Livingstone DE, Eliasson M, Johnson O, Andrew R, Olsson T.

J Clin Endocrinol Metab. 2002 Jul;87(7):3330-6.PMID: 12107245 [PubMed - indexed for MEDLINE]Related articlesFree article

Weight loss increases 11beta-hydroxysteroid dehydrogenase type 1 expression in human adipose tissue.

Tomlinson JW, Moore JS, Clark PM, Holder G, Shakespeare L, Stewart PM.

J Clin Endocrinol Metab. 2004 Jun;89(6):2711-6.PMID: 15181046 [PubMed - indexed for MEDLINE]Related articlesFree article

Extra-adrenal regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1: physiological regulator and pharmacological target for energy partitioning.

Walker BR.

Proc Nutr Soc. 2007 Feb;66(1):1-8.PMID: 17343766 [PubMed - indexed for MEDLINE]Related articles

Impaired glucose tolerance and insulin resistance are associated with increased adipose 11beta-hydroxysteroid dehydrogenase type 1 expression and elevated hepatic 5alpha-reductase activity.

Tomlinson JW, Finney J, Gay C, Hughes BA, Hughes SV, Stewart PM.

Diabetes. 2008 Oct;57(10):2652-60. Epub 2008 Jul 15.PMID: 18633104 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 in obesity.

Wake DJ, Walker BR.

Endocrine. 2006 Feb;29(1):101-8. Review.PMID: 16622297 [PubMed - indexed for MEDLINE]Related articles