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    Results: 1 to 20 of 258

    1.

    Functional and molecular defects of pancreatic islets in human type 2 diabetes.

    Del Guerra S, Lupi R, Marselli L, Masini M, Bugliani M, Sbrana S, Torri S, Pollera M, Boggi U, Mosca F, Del Prato S, Marchetti P.

    Diabetes. 2005 Mar;54(3):727-35.PMID: 15734849 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Insulin secretion defects of human type 2 diabetic islets are corrected in vitro by a new reactive oxygen species scavenger.

    Lupi R, Del Guerra S, Mancarella R, Novelli M, Valgimigli L, Pedulli GF, Paolini M, Soleti A, Filipponi F, Mosca F, Boggi U, Del Prato S, Masiello P, Marchetti P.

    Diabetes Metab. 2007 Nov;33(5):340-5. Epub 2007 Jul 9.PMID: 17616474 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin.

    Marchetti P, Del Guerra S, Marselli L, Lupi R, Masini M, Pollera M, Bugliani M, Boggi U, Vistoli F, Mosca F, Del Prato S.

    J Clin Endocrinol Metab. 2004 Nov;89(11):5535-41.PMID: 15531508 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Role of oxidative stress in pancreatic beta-cell dysfunction.

    Kajimoto Y, Kaneto H.

    Ann N Y Acad Sci. 2004 Apr;1011:168-76.PMID: 15126294 [PubMed - indexed for MEDLINE]Related articles

    5.

    Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat.

    Tokuyama Y, Sturis J, DePaoli AM, Takeda J, Stoffel M, Tang J, Sun X, Polonsky KS, Bell GI.

    Diabetes. 1995 Dec;44(12):1447-57.PMID: 7589853 [PubMed - indexed for MEDLINE]Related articles

    6.

    The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.

    Marchetti P, Bugliani M, Lupi R, Marselli L, Masini M, Boggi U, Filipponi F, Weir GC, Eizirik DL, Cnop M.

    Diabetologia. 2007 Dec;50(12):2486-94. Epub 2007 Sep 30.PMID: 17906960 [PubMed - indexed for MEDLINE]Related articles

    7.

    Improved insulin secretory function and reduced chemotactic properties after tissue culture of islets from type 1 diabetic patients.

    Lupi R, Marselli L, Dionisi S, Del Guerra S, Boggi U, Del Chiaro M, Lencioni C, Bugliani M, Mosca F, Di Mario U, Del Prato S, Dotta F, Marchetti P.

    Diabetes Metab Res Rev. 2004 May-Jun;20(3):246-51.PMID: 15133757 [PubMed - indexed for MEDLINE]Related articles

    8.

    Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion.

    Ling C, Del Guerra S, Lupi R, Rönn T, Granhall C, Luthman H, Masiello P, Marchetti P, Groop L, Del Prato S.

    Diabetologia. 2008 Apr;51(4):615-22. Epub 2008 Feb 13.PMID: 18270681 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Alteration of beta-cell constitutive NO synthase activity is involved in the abnormal insulin response to arginine in a new rat model of type 2 diabetes.

    Novelli M, Pocai A, Lajoix AD, Beffy P, Bezzi D, Marchetti P, Gross R, Masiello P.

    Mol Cell Endocrinol. 2004 Apr 30;219(1-2):77-82.PMID: 15149729 [PubMed - indexed for MEDLINE]Related articles

    10.

    The direct effects of the angiotensin-converting enzyme inhibitors, zofenoprilat and enalaprilat, on isolated human pancreatic islets.

    Lupi R, Del Guerra S, Bugliani M, Boggi U, Mosca F, Torri S, Del Prato S, Marchetti P.

    Eur J Endocrinol. 2006 Feb;154(2):355-61.PMID: 16452552 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Functional and morphological alterations of mitochondria in pancreatic beta cells from type 2 diabetic patients.

    Anello M, Lupi R, Spampinato D, Piro S, Masini M, Boggi U, Del Prato S, Rabuazzo AM, Purrello F, Marchetti P.

    Diabetologia. 2005 Feb;48(2):282-9. Epub 2005 Jan 15.PMID: 15654602 [PubMed - indexed for MEDLINE]Related articles

    12.

    Over-expression of AMP-activated protein kinase impairs pancreatic {beta}-cell function in vivo.

    Richards SK, Parton LE, Leclerc I, Rutter GA, Smith RM.

    J Endocrinol. 2005 Nov;187(2):225-35.PMID: 16293770 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets?

    Welsh N, Cnop M, Kharroubi I, Bugliani M, Lupi R, Marchetti P, Eizirik DL.

    Diabetes. 2005 Nov;54(11):3238-44.PMID: 16249450 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Islet neuronal abnormalities associated with impaired insulin secretion in type 2 diabetes in the Chinese hamster.

    Kohnert KD, Axcrona UM, Hehmke B, Klöting I, Sundler F, Ahrén B.

    Regul Pept. 1999 Jun 30;82(1-3):71-9.PMID: 10458649 [PubMed - indexed for MEDLINE]Related articles

    15.

    Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects.

    Deng S, Vatamaniuk M, Huang X, Doliba N, Lian MM, Frank A, Velidedeoglu E, Desai NM, Koeberlein B, Wolf B, Barker CF, Naji A, Matschinsky FM, Markmann JF.

    Diabetes. 2004 Mar;53(3):624-32.PMID: 14988246 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    High glucose-induced impairment in insulin secretion is associated with reduction in islet glucokinase in a mouse model of susceptibility to islet dysfunction.

    Kooptiwut S, Kebede M, Zraika S, Visinoni S, Aston-Mourney K, Favaloro J, Tikellis C, Thomas MC, Forbes JM, Cooper ME, Dunlop M, Proietto J, Andrikopoulos S.

    J Mol Endocrinol. 2005 Aug;35(1):39-48.PMID: 16087720 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Insulin secretory function is impaired in isolated human islets carrying the Gly(972)-->Arg IRS-1 polymorphism.

    Marchetti P, Lupi R, Federici M, Marselli L, Masini M, Boggi U, Del Guerra S, Patanè G, Piro S, Anello M, Bergamini E, Purrello F, Lauro R, Mosca F, Sesti G, Del Prato S.

    Diabetes. 2002 May;51(5):1419-24.PMID: 11978638 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Enzymatic, metabolic and secretory patterns in human islets of type 2 (non-insulin-dependent) diabetic patients.

    Fernandez-Alvarez J, Conget I, Rasschaert J, Sener A, Gomis R, Malaisse WJ.

    Diabetologia. 1994 Feb;37(2):177-81.PMID: 8163052 [PubMed - indexed for MEDLINE]Related articles

    19.

    The possible mechanisms by which phanoside stimulates insulin secretion from rat islets.

    Hoa NK, Norberg A, Sillard R, Van Phan D, Thuan ND, Dzung DT, Jörnvall H, Ostenson CG.

    J Endocrinol. 2007 Feb;192(2):389-94.PMID: 17283239 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Inhibition of protein-tyrosine phosphatases stimulates insulin secretion in pancreatic islets of diabetic Goto-Kakizaki rats.

    Chen J, Ostenson CG.

    Pancreas. 2005 May;30(4):314-7.PMID: 15841039 [PubMed - indexed for MEDLINE]Related articles

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