PubMed

Munc18c heterozygous knockout mice display increased susceptibility for severe glucose intolerance.

Oh E, Spurlin BA, Pessin JE, Thurmond DC.

Diabetes. 2005 Mar;54(3):638-47.PMID: 15734838 [PubMed - indexed for MEDLINE]Related articlesFree article

Syntaxin 4 transgenic mice exhibit enhanced insulin-mediated glucose uptake in skeletal muscle.

Spurlin BA, Park SY, Nevins AK, Kim JK, Thurmond DC.

Diabetes. 2004 Sep;53(9):2223-31.PMID: 15331531 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipocytes from Munc18c-null mice show increased sensitivity to insulin-stimulated GLUT4 externalization.

Kanda H, Tamori Y, Shinoda H, Yoshikawa M, Sakaue M, Udagawa J, Otani H, Tashiro F, Miyazaki J, Kasuga M.

J Clin Invest. 2005 Feb;115(2):291-301.PMID: 15690082 [PubMed - indexed for MEDLINE]Related articlesFree article

High level overexpression of glucose transporter-4 driven by an adipose-specific promoter is maintained in transgenic mice on a high fat diet, but does not prevent impaired glucose tolerance.

Gnudi L, Tozzo E, Shepherd PR, Bliss JL, Kahn BB.

Endocrinology. 1995 Mar;136(3):995-1002.PMID: 7867610 [PubMed - indexed for MEDLINE]Related articles

Munc18c regulates insulin-stimulated glut4 translocation to the transverse tubules in skeletal muscle.

Khan AH, Thurmond DC, Yang C, Ceresa BP, Sigmund CD, Pessin JE.

J Biol Chem. 2001 Feb 9;276(6):4063-9. Epub 2000 Oct 27.PMID: 11054418 [PubMed - indexed for MEDLINE]Related articlesFree article

Syntaxin 4 heterozygous knockout mice develop muscle insulin resistance.

Yang C, Coker KJ, Kim JK, Mora S, Thurmond DC, Davis AC, Yang B, Williamson RA, Shulman GI, Pessin JE.

J Clin Invest. 2001 May;107(10):1311-8.PMID: 11375421 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular munc18c levels can modulate glucose transport rate and GLUT4 translocation in 3T3L1 cells.

Macaulay SL, Grusovin J, Stoichevska V, Ryan JM, Castelli LA, Ward CW.

FEBS Lett. 2002 Sep 25;528(1-3):154-60.PMID: 12297296 [PubMed - indexed for MEDLINE]Related articles

Regulation of insulin-stimulated GLUT4 translocation by Munc18c in 3T3L1 adipocytes.

Thurmond DC, Ceresa BP, Okada S, Elmendorf JS, Coker K, Pessin JE.

J Biol Chem. 1998 Dec 11;273(50):33876-83.PMID: 9837979 [PubMed - indexed for MEDLINE]Related articlesFree article

Discrimination of GLUT4 vesicle trafficking from fusion using a temperature-sensitive Munc18c mutant.

Thurmond DC, Pessin JE.

EMBO J. 2000 Jul 17;19(14):3565-75.PMID: 10899111 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance in tetracycline-repressible Munc18c transgenic mice.

Spurlin BA, Thomas RM, Nevins AK, Kim HJ, Kim YJ, Noh HL, Shulman GI, Kim JK, Thurmond DC.

Diabetes. 2003 Aug;52(8):1910-7.PMID: 12882905 [PubMed - indexed for MEDLINE]Related articlesFree article

Munc18c function is required for insulin-stimulated plasma membrane fusion of GLUT4 and insulin-responsive amino peptidase storage vesicles.

Thurmond DC, Kanzaki M, Khan AH, Pessin JE.

Mol Cell Biol. 2000 Jan;20(1):379-88.PMID: 10594040 [PubMed - indexed for MEDLINE]Related articlesFree article

A high fat diet impairs stimulation of glucose transport in muscle. Functional evaluation of potential mechanisms.

Hansen PA, Han DH, Marshall BA, Nolte LA, Chen MM, Mueckler M, Holloszy JO.

J Biol Chem. 1998 Oct 2;273(40):26157-63.PMID: 9748297 [PubMed - indexed for MEDLINE]Related articlesFree article

Tyrosine phosphorylation of Munc18c regulates platelet-derived growth factor-stimulated glucose transporter 4 translocation in 3T3L1 adipocytes.

Umahara M, Okada S, Yamada E, Saito T, Ohshima K, Hashimoto K, Yamada M, Shimizu H, Pessin JE, Mori M.

Endocrinology. 2008 Jan;149(1):40-9. Epub 2007 Oct 4.PMID: 17916632 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of knockout of the protein kinase C beta gene on glucose transport and glucose homeostasis.

Standaert ML, Bandyopadhyay G, Galloway L, Soto J, Ono Y, Kikkawa U, Farese RV, Leitges M.

Endocrinology. 1999 Oct;140(10):4470-7.PMID: 10499500 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase-zeta interacts with munc18c: role in GLUT4 trafficking.

Hodgkinson CP, Mander A, Sale GJ.

Diabetologia. 2005 Aug;48(8):1627-36. Epub 2005 Jun 29.PMID: 15986239 [PubMed - indexed for MEDLINE]Related articles

Increased expression of the SNARE accessory protein Munc18c in lipid-mediated insulin resistance.

Schlaepfer IR, Pulawa LK, Ferreira LD, James DE, Capell WH, Eckel RH.

J Lipid Res. 2003 Jun;44(6):1174-81. Epub 2003 Apr 16.PMID: 12700337 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance.

Zisman A, Peroni OD, Abel ED, Michael MD, Mauvais-Jarvis F, Lowell BB, Wojtaszewski JF, Hirshman MF, Virkamaki A, Goodyear LJ, Kahn CR, Kahn BB.

Nat Med. 2000 Aug;6(8):924-8.PMID: 10932232 [PubMed - indexed for MEDLINE]Related articles

Variation in type 2 diabetes--related traits in mouse strains susceptible to diet-induced obesity.

Rossmeisl M, Rim JS, Koza RA, Kozak LP.

Diabetes. 2003 Aug;52(8):1958-66.PMID: 12882911 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose-specific overexpression of GLUT4 reverses insulin resistance and diabetes in mice lacking GLUT4 selectively in muscle.

Carvalho E, Kotani K, Peroni OD, Kahn BB.

Am J Physiol Endocrinol Metab. 2005 Oct;289(4):E551-61. Epub 2005 May 31.PMID: 15928024 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered beta-cell distribution of pdx-1 and GLUT-2 after a short-term challenge with a high-fat diet in C57BL/6J mice.

Reimer MK, Ahrén B.

Diabetes. 2002 Feb;51 Suppl 1:S138-43.PMID: 11815473 [PubMed - indexed for MEDLINE]Related articlesFree article