PubMed

Peroxisome proliferator-activated receptor alpha gene variation influences age of onset and progression of type 2 diabetes.

Flavell DM, Ireland H, Stephens JW, Hawe E, Acharya J, Mather H, Hurel SJ, Humphries SE.

Diabetes. 2005 Feb;54(2):582-6.PMID: 15677519 [PubMed - indexed for MEDLINE]Related articlesFree article

Response to micronized fenofibrate treatment is associated with the peroxisome-proliferator-activated receptors alpha G/C intron7 polymorphism in subjects with type 2 diabetes.

Foucher C, Rattier S, Flavell DM, Talmud PJ, Humphries SE, Kastelein JJ, Ayyobi A, Pimstone S, Frohlich J, Ansquer JC, Steiner G; DAIS investigators.

Pharmacogenetics. 2004 Dec;14(12):823-9.PMID: 15608561 [PubMed - indexed for MEDLINE]Related articles

Mutation screening of the PPARalpha gene in type 2 diabetes associated with coronary heart disease.

Lacquemant C, Lepretre F, Pineda Torra I, Manraj M, Charpentier G, Ruiz J, Staels B, Froguel P.

Diabetes Metab. 2000 Nov;26(5):393-401.PMID: 11119019 [PubMed - indexed for MEDLINE]Related articlesFree article

Variation in the PPARalpha gene is associated with altered function in vitro and plasma lipid concentrations in Type II diabetic subjects.

Flavell DM, Pineda Torra I, Jamshidi Y, Evans D, Diamond JR, Elkeles RS, Bujac SR, Miller G, Talmud PJ, Staels B, Humphries SE.

Diabetologia. 2000 May;43(5):673-80.PMID: 10855543 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor gamma coactivator 1 alpha promoter polymorphisms are associated with early-onset type 2 diabetes mellitus in the Korean population.

Kim JH, Shin HD, Park BL, Cho YM, Kim SY, Lee HK, Park KS.

Diabetologia. 2005 Jul;48(7):1323-30. Epub 2005 Jun 4.PMID: 15937669 [PubMed - indexed for MEDLINE]Related articles

The peroxisome proliferator-activated receptor gamma coactivator-1 alpha gene (PGC-1alpha) is not associated with type 2 diabetes mellitus or body mass index among Hispanic and non Hispanic Whites from Colorado.

Nelson TL, Fingerlin TE, Moss L, Barmada MM, Ferrell RE, Norris JM.

Exp Clin Endocrinol Diabetes. 2007 Apr;115(4):268-75.PMID: 17479445 [PubMed - indexed for MEDLINE]Related articles

The Pro12Ala polymorphism of PPARgamma2 gene and susceptibility to type 2 diabetes mellitus in a Polish population.

Malecki MT, Frey J, Klupa T, Skupien J, Walus M, Mlynarski W, Sieradzki J.

Diabetes Res Clin Pract. 2003 Nov;62(2):105-11.PMID: 14581147 [PubMed - indexed for MEDLINE]Related articles

The peroxisome proliferator-activated receptor delta +294T/C polymorphism in relation to lipoprotein metabolism in patients with diabetes mellitus type 2 and in non-diabetic controls.

Gouni-Berthold I, Giannakidou E, Faust M, Berthold HK, Krone W.

Atherosclerosis. 2005 Dec;183(2):336-41. Epub 2005 Apr 19.PMID: 16285997 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor alpha L162V polymorphism in nonalcoholic steatohepatitis and genotype 1 hepatitis C virus-related liver steatosis.

Verdi H, Koytak ES, Onder O, Ergül AA, Cinar K, Idilman R, Erden E, Bozdayi AM, Yurdaydin C, Uzunalimoglu O, Bozkaya H.

J Investig Med. 2005 Nov;53(7):353-9.PMID: 16297361 [PubMed - indexed for MEDLINE]Related articles

Genetic determinants of the response to bezafibrate treatment in the lower extremity arterial disease event reduction (LEADER) trial.

Jamshidi Y, Flavell DM, Hawe E, MacCallum PK, Meade TW, Humphries SE.

Atherosclerosis. 2002 Jul;163(1):183-92.PMID: 12048138 [PubMed - indexed for MEDLINE]Related articles

Association of peroxisome proliferator-activated receptor delta +294T/C with body mass index and interaction with peroxisome proliferator-activated receptor alpha L162V.

Aberle J, Hopfer I, Beil FU, Seedorf U.

Int J Obes (Lond). 2006 Dec;30(12):1709-13. Epub 2006 Apr 25.PMID: 16652134 [PubMed - indexed for MEDLINE]Related articles

Single nucleotide polymorphisms of the peroxisome proliferator-activated receptor-alpha gene (PPARA) influence the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial.

Andrulionyte L, Kuulasmaa T, Chiasson JL, Laakso M; STOP-NIDDM Study Group.

Diabetes. 2007 Apr;56(4):1181-6. Epub 2007 Feb 22.PMID: 17317762 [PubMed - indexed for MEDLINE]Related articlesFree article

A polymorphism, L162V, in the peroxisome proliferator-activated receptor alpha (PPARalpha) gene is associated with lower body mass index in patients with non-insulin-dependent diabetes mellitus.

Evans D, Aberle J, Wendt D, Wolf A, Beisiegel U, Mann WA.

J Mol Med. 2001 May;79(4):198-204.PMID: 11409711 [PubMed - indexed for MEDLINE]Related articles

The relationship of the peroxisome proliferator-activated receptor-gamma 2 exon 2 and exon 6 gene polymorphism in Turkish type 2 diabetic patients with and without nephropathy.

Erdogan M, Karadeniz M, Eroglu Z, Tezcanli B, Selvi N, Yilmaz C.

Diabetes Res Clin Pract. 2007 Dec;78(3):355-9. Epub 2007 Aug 6.PMID: 17681394 [PubMed - indexed for MEDLINE]Related articles

Genetic variation at the adiponectin locus and risk of type 2 diabetes in women.

Hu FB, Doria A, Li T, Meigs JB, Liu S, Memisoglu A, Hunter D, Manson JE.

Diabetes. 2004 Jan;53(1):209-13.PMID: 14693717 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor alpha gene variants influence progression of coronary atherosclerosis and risk of coronary artery disease.

Flavell DM, Jamshidi Y, Hawe E, Pineda Torra I, Taskinen MR, Frick MH, Nieminen MS, Kesäniemi YA, Pasternack A, Staels B, Miller G, Humphries SE, Talmud PJ, Syvänne M.

Circulation. 2002 Mar 26;105(12):1440-5.PMID: 11914252 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationships between the functional PPARalpha Leu162Val polymorphism and obesity, type 2 diabetes, dyslipidaemia, and related quantitative traits in studies of 5799 middle-aged white people.

Sparsø T, Hussain MS, Andersen G, Hainerova I, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Mol Genet Metab. 2007 Feb;90(2):205-9. Epub 2006 Nov 28.PMID: 17129741 [PubMed - indexed for MEDLINE]Related articles

Haplotype analysis of the RAGE gene: identification of a haplotype marker for diabetic nephropathy in type 2 diabetes mellitus.

Kanková K, Stejskalová A, Hertlová M, Znojil V.

Nephrol Dial Transplant. 2005 Jun;20(6):1093-102. Epub 2005 Mar 24.PMID: 15790669 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms in the peroxisome proliferator activated receptor alpha gene are associated with levels of apolipoprotein CIII and triglyceride in African-Americans but not Caucasians.

Shin MJ, Kanaya AM, Krauss RM.

Atherosclerosis. 2008 Jun;198(2):313-9. Epub 2007 Dec 3.PMID: 18061194 [PubMed - indexed for MEDLINE]Related articlesFree article

The L162V polymorphism of the peroxisome proliferator activated receptor alpha gene (PPARA) is not associated with type 2 diabetes, BMI or body fat composition.

Silbernagel G, Stefan N, Hoffmann MM, Machicao-Arano F, Machann J, Schick F, Winkelmann BR, Boehm BO, Häring HU, Fritsche A, März W.

Exp Clin Endocrinol Diabetes. 2009 Mar;117(3):113-8. Epub 2008 Aug 25.PMID: 18726867 [PubMed - indexed for MEDLINE]Related articles