PubMed

beta-Cell Pdx1 expression is essential for the glucoregulatory, proliferative, and cytoprotective actions of glucagon-like peptide-1.

Li Y, Cao X, Li LX, Brubaker PL, Edlund H, Drucker DJ.

Diabetes. 2005 Feb;54(2):482-91.PMID: 15677506 [PubMed - indexed for MEDLINE]Related articlesFree article

Elimination of glucagon-like peptide 1R signaling does not modify weight gain and islet adaptation in mice with combined disruption of leptin and GLP-1 action.

Scrocchi LA, Hill ME, Saleh J, Perkins B, Drucker DJ.

Diabetes. 2000 Sep;49(9):1552-60.PMID: 10969840 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis.

Li Y, Hansotia T, Yusta B, Ris F, Halban PA, Drucker DJ.

J Biol Chem. 2003 Jan 3;278(1):471-8. Epub 2002 Oct 29.PMID: 12409292 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of glucagon-like peptide 1 (GLP-1) actions essential for glucose homeostasis in mice with disruption of GLP-1 receptor signaling.

Scrocchi LA, Marshall BA, Cook SM, Brubaker PL, Drucker DJ.

Diabetes. 1998 Apr;47(4):632-9.PMID: 9568697 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic exposure to GLP-1R agonists promotes homologous GLP-1 receptor desensitization in vitro but does not attenuate GLP-1R-dependent glucose homeostasis in vivo.

Baggio LL, Kim JG, Drucker DJ.

Diabetes. 2004 Dec;53 Suppl 3:S205-14.PMID: 15561912 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of endogenous glucagon-like peptide-1 in islet regeneration after partial pancreatectomy.

De León DD, Deng S, Madani R, Ahima RS, Drucker DJ, Stoffers DA.

Diabetes. 2003 Feb;52(2):365-71.PMID: 12540609 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptides: regulators of cell proliferation, differentiation, and apoptosis.

Drucker DJ.

Mol Endocrinol. 2003 Feb;17(2):161-71. Review.PMID: 12554744 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats.

Perfetti R, Zhou J, Doyle ME, Egan JM.

Endocrinology. 2000 Dec;141(12):4600-5.PMID: 11108273 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1.

Doyle ME, Egan JM.

Recent Prog Horm Res. 2001;56:377-99. Review.PMID: 11237222 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, regulates fasting glycemia and nonenteral glucose clearance in mice.

Baggio L, Kieffer TJ, Drucker DJ.

Endocrinology. 2000 Oct;141(10):3703-9.PMID: 11014225 [PubMed - indexed for MEDLINE]Related articlesFree article

An albumin-exendin-4 conjugate engages central and peripheral circuits regulating murine energy and glucose homeostasis.

Baggio LL, Huang Q, Cao X, Drucker DJ.

Gastroenterology. 2008 Apr;134(4):1137-47. Epub 2008 Jan 11.PMID: 18313669 [PubMed - indexed for MEDLINE]Related articles

Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors.

Hansotia T, Baggio LL, Delmeire D, Hinke SA, Yamada Y, Tsukiyama K, Seino Y, Holst JJ, Schuit F, Drucker DJ.

Diabetes. 2004 May;53(5):1326-35.PMID: 15111503 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide 1 increases glucose-dependent activity of the homeoprotein IDX-1 transactivating domain in pancreatic beta-cells.

Hussain MA, Habener JF.

Biochem Biophys Res Commun. 2000 Aug 11;274(3):616-9.PMID: 10924326 [PubMed - indexed for MEDLINE]Related articles

Sustained expression of exendin-4 does not perturb glucose homeostasis, beta-cell mass, or food intake in metallothionein-preproexendin transgenic mice.

Baggio L, Adatia F, Bock T, Brubaker PL, Drucker DJ.

J Biol Chem. 2000 Nov 3;275(44):34471-7.PMID: 10952981 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure.

Baggio LL, Huang Q, Brown TJ, Drucker DJ.

Gastroenterology. 2004 Aug;127(2):546-58.PMID: 15300587 [PubMed - indexed for MEDLINE]Related articles

The glucagon-like peptide-1 receptor agonist oxyntomodulin enhances beta-cell function but does not inhibit gastric emptying in mice.

Maida A, Lovshin JA, Baggio LL, Drucker DJ.

Endocrinology. 2008 Nov;149(11):5670-8. Epub 2008 Jul 31.PMID: 18669601 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1 and islet lipolysis.

Sörhede Winzell M, Ahrén B.

Horm Metab Res. 2004 Nov-Dec;36(11-12):795-803.PMID: 15655711 [PubMed - indexed for MEDLINE]Related articles

A recombinant human glucagon-like peptide (GLP)-1-albumin protein (albugon) mimics peptidergic activation of GLP-1 receptor-dependent pathways coupled with satiety, gastrointestinal motility, and glucose homeostasis.

Baggio LL, Huang Q, Brown TJ, Drucker DJ.

Diabetes. 2004 Sep;53(9):2492-500.PMID: 15331566 [PubMed - indexed for MEDLINE]Related articlesFree article

GIP and GLP-1 as incretin hormones: lessons from single and double incretin receptor knockout mice.

Hansotia T, Drucker DJ.

Regul Pept. 2005 Jun 15;128(2):125-34. Review.PMID: 15780432 [PubMed - indexed for MEDLINE]Related articles

Altered cAMP and Ca2+ signaling in mouse pancreatic islets with glucagon-like peptide-1 receptor null phenotype.

Flamez D, Gilon P, Moens K, Van Breusegem A, Delmeire D, Scrocchi LA, Henquin JC, Drucker DJ, Schuit F.

Diabetes. 1999 Oct;48(10):1979-86.PMID: 10512362 [PubMed - indexed for MEDLINE]Related articlesFree article