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    Results: 1 to 20 of 701

    1.

    Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells.

    Cardozo AK, Ortis F, Storling J, Feng YM, Rasschaert J, Tonnesen M, Van Eylen F, Mandrup-Poulsen T, Herchuelz A, Eizirik DL.

    Diabetes. 2005 Feb;54(2):452-61.PMID: 15677503 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    IL-1beta caused pancreatic beta-cells apoptosis is mediated in part by endoplasmic reticulum stress via the induction of endoplasmic reticulum Ca2+ release through the c-Jun N-terminal kinase pathway.

    Wang Q, Zhang H, Zhao B, Fei H.

    Mol Cell Biochem. 2009 Apr;324(1-2):183-90. Epub 2008 Dec 25.PMID: 19109696 [PubMed - indexed for MEDLINE]Related articles

    3.

    Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress.

    Kharroubi I, Ladrière L, Cardozo AK, Dogusan Z, Cnop M, Eizirik DL.

    Endocrinology. 2004 Nov;145(11):5087-96. Epub 2004 Aug 5.PMID: 15297438 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Interferon-gamma potentiates endoplasmic reticulum stress-induced death by reducing pancreatic beta cell defence mechanisms.

    Pirot P, Eizirik DL, Cardozo AK.

    Diabetologia. 2006 Jun;49(6):1229-36. Epub 2006 Apr 8.PMID: 16604358 [PubMed - indexed for MEDLINE]Related articles

    5.

    Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling.

    Akerfeldt MC, Howes J, Chan JY, Stevens VA, Boubenna N, McGuire HM, King C, Biden TJ, Laybutt DR.

    Diabetes. 2008 Nov;57(11):3034-44. Epub 2008 Jun 30.PMID: 18591394 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Transcriptional regulation of the endoplasmic reticulum stress gene chop in pancreatic insulin-producing cells.

    Pirot P, Ortis F, Cnop M, Ma Y, Hendershot LM, Eizirik DL, Cardozo AK.

    Diabetes. 2007 Apr;56(4):1069-77.PMID: 17395747 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Inhibition of nuclear factor-kappaB or Bax prevents endoplasmic reticulum stress- but not nitric oxide-mediated apoptosis in INS-1E cells.

    Tonnesen MF, Grunnet LG, Friberg J, Cardozo AK, Billestrup N, Eizirik DL, Størling J, Mandrup-Poulsen T.

    Endocrinology. 2009 Sep;150(9):4094-103. Epub 2009 Jun 25.PMID: 19556421 [PubMed - indexed for MEDLINE]Related articles

    8.

    The role of interferon regulatory factor-1 in cytokine-induced mRNA expression and cell death in murine pancreatic beta-cells.

    Pavlovic D, Chen MC, Gysemans CA, Mathieu C, Eizirik DL.

    Eur Cytokine Netw. 1999 Sep;10(3):403-12.PMID: 10477397 [PubMed - indexed for MEDLINE]Related articles

    9.

    Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

    Luciani DS, Gwiazda KS, Yang TL, Kalynyak TB, Bychkivska Y, Frey MH, Jeffrey KD, Sampaio AV, Underhill TM, Johnson JD.

    Diabetes. 2009 Feb;58(2):422-32. Epub 2008 Nov 25.PMID: 19033399 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Carbon monoxide induces heme oxygenase-1 via activation of protein kinase R-like endoplasmic reticulum kinase and inhibits endothelial cell apoptosis triggered by endoplasmic reticulum stress.

    Kim KM, Pae HO, Zheng M, Park R, Kim YM, Chung HT.

    Circ Res. 2007 Oct 26;101(9):919-27. Epub 2007 Sep 6.PMID: 17823375 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.

    Cunha DA, Hekerman P, Ladrière L, Bazarra-Castro A, Ortis F, Wakeham MC, Moore F, Rasschaert J, Cardozo AK, Bellomo E, Overbergh L, Mathieu C, Lupi R, Hai T, Herchuelz A, Marchetti P, Rutter GA, Eizirik DL, Cnop M.

    J Cell Sci. 2008 Jul 15;121(Pt 14):2308-18. Epub 2008 Jun 17.PMID: 18559892 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway.

    Oyadomari S, Takeda K, Takiguchi M, Gotoh T, Matsumoto M, Wada I, Akira S, Araki E, Mori M.

    Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10845-50. Epub 2001 Aug 28.PMID: 11526215 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Double-stranded RNA cooperates with interferon-gamma and IL-1 beta to induce both chemokine expression and nuclear factor-kappa B-dependent apoptosis in pancreatic beta-cells: potential mechanisms for viral-induced insulitis and beta-cell death in type 1 diabetes mellitus.

    Liu D, Cardozo AK, Darville MI, Eizirik DL.

    Endocrinology. 2002 Apr;143(4):1225-34.PMID: 11897677 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    The sarco/endoplasmic reticulum calcium-ATPase 2b is an endoplasmic reticulum stress-inducible protein.

    Caspersen C, Pedersen PS, Treiman M.

    J Biol Chem. 2000 Jul 21;275(29):22363-72.PMID: 10748035 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Endoplasmic reticulum stress induced by aqueous extracts of cigarette smoke in 3T3 cells activates the unfolded-protein-response-dependent PERK pathway of cell survival.

    Hengstermann A, Müller T.

    Free Radic Biol Med. 2008 Mar 15;44(6):1097-107. Epub 2007 Dec 23.PMID: 18206657 [PubMed - indexed for MEDLINE]Related articles

    16.

    Dynamic imaging of endoplasmic reticulum Ca2+ concentration in insulin-secreting MIN6 Cells using recombinant targeted cameleons: roles of sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA)-2 and ryanodine receptors.

    Varadi A, Rutter GA.

    Diabetes. 2002 Feb;51 Suppl 1:S190-201.PMID: 11815480 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    The role for endoplasmic reticulum stress in diabetes mellitus.

    Eizirik DL, Cardozo AK, Cnop M.

    Endocr Rev. 2008 Feb;29(1):42-61. Epub 2007 Nov 29. Review.PMID: 18048764 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Endoplasmic reticulum stress as a correlate of cytotoxicity in human tumor cells exposed to diindolylmethane in vitro.

    Sun S, Han J, Ralph WM Jr, Chandrasekaran A, Liu K, Auborn KJ, Carter TH.

    Cell Stress Chaperones. 2004 Mar;9(1):76-87.PMID: 15270080 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    STAT5 activation by human GH protects insulin-producing cells against interleukin-1beta, interferon-gamma and tumour necrosis factor-alpha-induced apoptosis independent of nitric oxide production.

    Jensen J, Galsgaard ED, Karlsen AE, Lee YC, Nielsen JH.

    J Endocrinol. 2005 Oct;187(1):25-36.PMID: 16214938 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Sarco/endoplasmic reticulum calcium ATPase-2 expression is regulated by ATF6 during the endoplasmic reticulum stress response: intracellular signaling of calcium stress in a cardiac myocyte model system.

    Thuerauf DJ, Hoover H, Meller J, Hernandez J, Su L, Andrews C, Dillmann WH, McDonough PM, Glembotski CC.

    J Biol Chem. 2001 Dec 21;276(51):48309-17. Epub 2001 Oct 10.PMID: 11595740 [PubMed - indexed for MEDLINE]Related articlesFree article

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