PubMed

Glucagon-like peptide 1 can directly protect the heart against ischemia/reperfusion injury.

Bose AK, Mocanu MM, Carr RD, Brand CL, Yellon DM.

Diabetes. 2005 Jan;54(1):146-51.PMID: 15616022 [PubMed - indexed for MEDLINE]Related articlesFree article

Signalling pathways activated by glucagon-like peptide-1 (7-36) amide in the rat heart and their role in protection against ischaemia.

Huisamen B, Genade S, Lochner A.

Cardiovasc J Afr. 2008 Mar-Apr;19(2):77-83.PMID: 18516352 [PubMed - indexed for MEDLINE]Related articlesFree article

Myocardial ischaemia-reperfusion injury is attenuated by intact glucagon like peptide-1 (GLP-1) in the in vitro rat heart and may involve the p70s6K pathway.

Bose AK, Mocanu MM, Carr RD, Yellon DM.

Cardiovasc Drugs Ther. 2007 Aug;21(4):253-6.PMID: 17541736 [PubMed - indexed for MEDLINE]Related articles

Urocortin protects the heart from reperfusion injury via upregulation of p42/p44 MAPK signaling pathway.

Schulman D, Latchman DS, Yellon DM.

Am J Physiol Heart Circ Physiol. 2002 Oct;283(4):H1481-8. Epub 2002 Jun 13.PMID: 12234800 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects and mechanism of glucagon-like peptide-1 on injury of rats cardiomyocytes induced by hypoxia-reoxygenation.

Xie Y, Wang SX, Sha WW, Zhou X, Wang WL, Han LP, Li DQ, Yu DM.

Chin Med J (Engl). 2008 Nov 5;121(21):2134-8.PMID: 19080172 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of p38 mitogen-activated protein kinase abolishes insulin-mediated myocardial protection against ischemia-reperfusion injury.

Chai W, Wu Y, Li G, Cao W, Yang Z, Liu Z.

Am J Physiol Endocrinol Metab. 2008 Jan;294(1):E183-9. Epub 2007 Nov 14.PMID: 18003719 [PubMed - indexed for MEDLINE]Related articlesFree article

Pioglitazone mimics preconditioning in the isolated perfused rat heart: a role for the prosurvival kinases PI3K and P42/44MAPK.

Wynne AM, Mocanu MM, Yellon DM.

J Cardiovasc Pharmacol. 2005 Dec;46(6):817-22.PMID: 16306807 [PubMed - indexed for MEDLINE]Related articles

Antagonism of rat beta-cell voltage-dependent K+ currents by exendin 4 requires dual activation of the cAMP/protein kinase A and phosphatidylinositol 3-kinase signaling pathways.

MacDonald PE, Wang X, Xia F, El-kholy W, Targonsky ED, Tsushima RG, Wheeler MB.

J Biol Chem. 2003 Dec 26;278(52):52446-53. Epub 2003 Oct 16.PMID: 14565957 [PubMed - indexed for MEDLINE]Related articlesFree article

SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts.

Strande JL, Hsu A, Su J, Fu X, Gross GJ, Baker JE.

Basic Res Cardiol. 2007 Jul;102(4):350-8. Epub 2007 Apr 30.PMID: 17468933 [PubMed - indexed for MEDLINE]Related articles

Glucagon-like peptide-1 limits myocardial stunning following brief coronary occlusion and reperfusion in conscious canines.

Nikolaidis LA, Doverspike A, Hentosz T, Zourelias L, Shen YT, Elahi D, Shannon RP.

J Pharmacol Exp Ther. 2005 Jan;312(1):303-8. Epub 2004 Sep 8.PMID: 15356213 [PubMed - indexed for MEDLINE]Related articlesFree article

Protective effects of GLP-1 analogues exendin-4 and GLP-1(9-36) amide against ischemia-reperfusion injury in rat heart.

Sonne DP, Engstrøm T, Treiman M.

Regul Pept. 2008 Feb 7;146(1-3):243-9. Epub 2007 Oct 13.PMID: 17976835 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of erythropoietin-mediated cardioprotection during ischemia-reperfusion injury: role of protein kinase C and phosphatidylinositol 3-kinase signaling.

Hanlon PR, Fu P, Wright GL, Steenbergen C, Arcasoy MO, Murphy E.

FASEB J. 2005 Aug;19(10):1323-5. Epub 2005 Jun 9.PMID: 15946993 [PubMed - indexed for MEDLINE]Related articlesFree article

Meat hydrolysate and essential amino acid-induced glucagon-like peptide-1 secretion, in the human NCI-H716 enteroendocrine cell line, is regulated by extracellular signal-regulated kinase1/2 and p38 mitogen-activated protein kinases.

Reimer RA.

J Endocrinol. 2006 Oct;191(1):159-70.PMID: 17065399 [PubMed - indexed for MEDLINE]Related articlesFree article

Cardioprotection induced by hydrogen sulfide preconditioning involves activation of ERK and PI3K/Akt pathways.

Hu Y, Chen X, Pan TT, Neo KL, Lee SW, Khin ES, Moore PK, Bian JS.

Pflugers Arch. 2008 Jan;455(4):607-16. Epub 2007 Aug 1.PMID: 17674030 [PubMed - indexed for MEDLINE]Related articles

Glucagon-like peptide-1 increases cAMP but fails to augment contraction in adult rat cardiac myocytes.

Vila Petroff MG, Egan JM, Wang X, Sollott SJ.

Circ Res. 2001 Aug 31;89(5):445-52.PMID: 11532906 [PubMed - indexed for MEDLINE]Related articlesFree article

PI3 kinase and not p42/p44 appears to be implicated in the protection conferred by ischemic preconditioning.

Mocanu MM, Bell RM, Yellon DM.

J Mol Cell Cardiol. 2002 Jun;34(6):661-8.PMID: 12054853 [PubMed - indexed for MEDLINE]Related articles

Erythropoietin protects the myocardium against reperfusion injury in vitro and in vivo.

Bullard AJ, Govewalla P, Yellon DM.

Basic Res Cardiol. 2005 Sep;100(5):397-403. Epub 2005 Jun 10.PMID: 15944807 [PubMed - indexed for MEDLINE]Related articles

Harnessing the therapeutic potential of glucagon-like peptide-1: a critical review.

Baggio LL, Drucker DJ.

Treat Endocrinol. 2002;1(2):117-25. Review.PMID: 15765627 [PubMed - indexed for MEDLINE]Related articles

Inhibition of LINE-1 expression in the heart decreases ischemic damage by activation of Akt/PKB signaling.

Lucchinetti E, Feng J, Silva R, Tolstonog GV, Schaub MC, Schumann GG, Zaugg M.

Physiol Genomics. 2006 Apr 13;25(2):314-24. Epub 2006 Jan 17.PMID: 16418318 [PubMed - indexed for MEDLINE]Related articlesFree article

Stimulation of pancreatic beta-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways.

Friedrichsen BN, Neubauer N, Lee YC, Gram VK, Blume N, Petersen JS, Nielsen JH, Møldrup A.

J Endocrinol. 2006 Mar;188(3):481-92.PMID: 16522728 [PubMed - indexed for MEDLINE]Related articlesFree article