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    Results: 1 to 20 of 198

    1.

    Uncoupling of nutrient metabolism from insulin secretion by overexpression of cytosolic phospholipase A(2).

    Milne HM, Burns CJ, Squires PE, Evans ND, Pickup J, Jones PM, Persaud SJ.

    Diabetes. 2005 Jan;54(1):116-24.PMID: 15616018 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    A key role for beta-cell cytosolic phospholipase A(2) in the maintenance of insulin stores but not in the initiation of insulin secretion.

    Persaud SJ, Roderigo-Milne HM, Squires PE, Sugden D, Wheeler-Jones CP, Marsh PJ, Belin VD, Luther MJ, Jones PM.

    Diabetes. 2002 Jan;51(1):98-104.PMID: 11756328 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action.

    Chan CB, De Leo D, Joseph JW, McQuaid TS, Ha XF, Xu F, Tsushima RG, Pennefather PS, Salapatek AM, Wheeler MB.

    Diabetes. 2001 Jun;50(6):1302-10.PMID: 11375330 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Effect of 17beta-estradiol on insulin secretion and cytosolic calcium in Min6 mouse insulinoma cells and human islets of Langerhans.

    Al-Majed HT, Squires PE, Persaud SJ, Huang GC, Amiel S, Whitehouse BJ, Jones PM.

    Pancreas. 2005 May;30(4):307-13.PMID: 15841038 [PubMed - indexed for MEDLINE]Related articles

    5.

    Acute overexpression of lactate dehydrogenase-A perturbs beta-cell mitochondrial metabolism and insulin secretion.

    Ainscow EK, Zhao C, Rutter GA.

    Diabetes. 2000 Jul;49(7):1149-55.PMID: 10909972 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Effect of mitochondrial and/or cytosolic glycerol 3-phosphate dehydrogenase overexpression on glucose-stimulated insulin secretion from MIN6 and HIT cells.

    Ishihara H, Nakazaki M, Kanegae Y, Inukai K, Asano T, Katagiri H, Yazaki Y, Kikuchi M, Miyazaki J, Saito I, Oka Y.

    Diabetes. 1996 Sep;45(9):1238-44.PMID: 8772729 [PubMed - indexed for MEDLINE]Related articles

    7.

    Association of upregulated activity of K(ATP) channels with impaired insulin secretion in UCP1-expressing insulinoma cells.

    Nakazaki M, Kakei M, Ishihara H, Koriyama N, Hashiguchi H, Aso K, Fukudome M, Oka Y, Yada T, Tei C.

    J Physiol. 2002 May 1;540(Pt 3):781-9.PMID: 11986368 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Direct regulation of insulin secretion by angiotensin II in human islets of Langerhans.

    Ramracheya RD, Muller DS, Wu Y, Whitehouse BJ, Huang GC, Amiel SA, Karalliedde J, Viberti G, Jones PM, Persaud SJ.

    Diabetologia. 2006 Feb;49(2):321-31. Epub 2006 Jan 17.PMID: 16416272 [PubMed - indexed for MEDLINE]Related articles

    9.

    Repetitive mitochondrial Ca2+ signals synchronize with cytosolic Ca2+ oscillations in the pancreatic beta-cell line, MIN6.

    Nakazaki M, Ishihara H, Kakei M, Inukai K, Asano T, Miyazaki JI, Tanaka H, Kikuchi M, Yada T, Oka Y.

    Diabetologia. 1998 Mar;41(3):279-86.PMID: 9541167 [PubMed - indexed for MEDLINE]Related articles

    10.

    Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression.

    Joseph JW, Koshkin V, Saleh MC, Sivitz WI, Zhang CY, Lowell BB, Chan CB, Wheeler MB.

    J Biol Chem. 2004 Dec 3;279(49):51049-56. Epub 2004 Sep 23.PMID: 15448158 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Taurine increases glucose sensitivity of UCP2-overexpressing beta-cells by ameliorating mitochondrial metabolism.

    Han J, Bae JH, Kim SY, Lee HY, Jang BC, Lee IK, Cho CH, Lim JG, Suh SI, Kwon TK, Park JW, Ryu SY, Ho WK, Earm YE, Song DK.

    Am J Physiol Endocrinol Metab. 2004 Nov;287(5):E1008-18. Epub 2004 Jul 20.PMID: 15265758 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Role and mechanism of rosiglitazone on the impairment of insulin secretion induced by free fatty acids on isolated rat islets.

    Tian JY, Li G, Gu YY, Zhang HL, Zhou WZ, Wang X, Zhu HD, Luo TH, Luo M.

    Chin Med J (Engl). 2006 Apr 5;119(7):574-80.PMID: 16620699 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    ACTH stimulates insulin secretion from MIN6 cells and primary mouse and human islets of Langerhans.

    Al-Majed HT, Jones PM, Persaud SJ, Sugden D, Huang GC, Amiel S, Whitehouse BJ.

    J Endocrinol. 2004 Jan;180(1):155-66.PMID: 14709154 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets.

    Chan CB, MacDonald PE, Saleh MC, Johns DC, Marbàn E, Wheeler MB.

    Diabetes. 1999 Jul;48(7):1482-6.PMID: 10389858 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Creation and characterization of a mitochondrial DNA-depleted pancreatic beta-cell line: impaired insulin secretion induced by glucose, leucine, and sulfonylureas.

    Tsuruzoe K, Araki E, Furukawa N, Shirotani T, Matsumoto K, Kaneko K, Motoshima H, Yoshizato K, Shirakami A, Kishikawa H, Miyazaki J, Shichiri M.

    Diabetes. 1998 Apr;47(4):621-31.PMID: 9568696 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    The role of cytosolic phospholipase A(2) in insulin secretion.

    Jones PM, Burns CJ, Belin VD, Roderigo-Milne HM, Persaud SJ.

    Diabetes. 2004 Feb;53 Suppl 1:S172-8.PMID: 14749284 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion.

    Zhou YP, Pena JC, Roe MW, Mittal A, Levisetti M, Baldwin AC, Pugh W, Ostrega D, Ahmed N, Bindokas VP, Philipson LH, Hanahan D, Thompson CB, Polonsky KS.

    Am J Physiol Endocrinol Metab. 2000 Feb;278(2):E340-51.PMID: 10662719 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Uncoupling protein 2: a possible link between fatty acid excess and impaired glucose-induced insulin secretion?

    Lameloise N, Muzzin P, Prentki M, Assimacopoulos-Jeannet F.

    Diabetes. 2001 Apr;50(4):803-9.PMID: 11289045 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Glucose-dependent modulation of insulin secretion and intracellular calcium ions by GKA50, a glucokinase activator.

    Johnson D, Shepherd RM, Gill D, Gorman T, Smith DM, Dunne MJ.

    Diabetes. 2007 Jun;56(6):1694-702. Epub 2007 Mar 14.PMID: 17360975 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Ca2+ controls slow NAD(P)H oscillations in glucose-stimulated mouse pancreatic islets.

    Luciani DS, Misler S, Polonsky KS.

    J Physiol. 2006 Apr 15;572(Pt 2):379-92. Epub 2006 Feb 2.PMID: 16455690 [PubMed - indexed for MEDLINE]Related articlesFree article

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