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Islet-infiltrating B-cells in nonobese diabetic mice predominantly target nervous system elements.
Carrillo J, Puertas MC, Alba A, Ampudia RM, Pastor X, Planas R, Riutort N, Alonso N, Pujol-Borrell R, Santamaria P, Vives-Pi M, Verdaguer J.
Diabetes. 2005 Jan;54(1):69-77.PMID: 15616012 [PubMed - indexed for MEDLINE]Related articlesFree article
I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet beta cells of nonobese diabetic mice.
Noorchashm H, Lieu YK, Noorchashm N, Rostami SY, Greeley SA, Schlachterman A, Song HK, Noto LE, Jevnikar AM, Barker CF, Naji A.
J Immunol. 1999 Jul 15;163(2):743-50.PMID: 10395666 [PubMed - indexed for MEDLINE]Related articlesFree article
Dysregulated B7-1 and B7-2 expression on nonobese diabetic mouse B cells is associated with increased T cell costimulation and the development of insulitis.
Hussain S, Delovitch TL.
J Immunol. 2005 Jan 15;174(2):680-7.PMID: 15634886 [PubMed - indexed for MEDLINE]Related articlesFree article
Flow cytometric enumeration of mononuclear cell populations infiltrating the islets of Langerhans in prediabetic NOD mice: development of a model of autoimmune insulitis for type I diabetes.
Jarpe AJ, Hickman MR, Anderson JT, Winter WE, Peck AB.
Reg Immunol. 1990-1991;3(6):305-17.PMID: 2132756 [PubMed - indexed for MEDLINE]Related articles
Peripherin is a relevant neuroendocrine autoantigen recognized by islet-infiltrating B lymphocytes.
Puertas MC, Carrillo J, Pastor X, Ampudia RM, Planas R, Alba A, Bruno R, Pujol-Borrell R, Estanyol JM, Vives-Pi M, Verdaguer J.
J Immunol. 2007 May 15;178(10):6533-9.PMID: 17475883 [PubMed - indexed for MEDLINE]Related articlesFree article
Evidence for the role of CD8+ cytotoxic T cells in the destruction of pancreatic beta-cells in nonobese diabetic mice.
Nagata M, Santamaria P, Kawamura T, Utsugi T, Yoon JW.
J Immunol. 1994 Feb 15;152(4):2042-50.PMID: 7907110 [PubMed - indexed for MEDLINE]Related articles
Sex steroids influence pancreatic islet hypertrophy and subsequent autoimmune infiltration in nonobese diabetic (NOD) and NODscid mice.
Rosmalen JG, Pigmans MJ, Kersseboom R, Drexhage HA, Leenen PJ, Homo-Delarche F.
Lab Invest. 2001 Feb;81(2):231-9.PMID: 11232645 [PubMed - indexed for MEDLINE]Related articles
Cross-priming of diabetogenic T cells dissociated from CTL-induced shedding of beta cell autoantigens.
Yamanouchi J, Verdaguer J, Han B, Amrani A, Serra P, Santamaria P.
J Immunol. 2003 Dec 15;171(12):6900-9.PMID: 14662897 [PubMed - indexed for MEDLINE]Related articlesFree article
Differential impact of T cell repertoire diversity in diabetes-prone or -resistant IL-10 transgenic mice.
Balasa B, Lee J, Sarvetnick N.
Cell Immunol. 1999 May 1;193(2):170-8.PMID: 10222059 [PubMed - indexed for MEDLINE]Related articles
Phenotype and functional characteristics of islet-infiltrating B-cells suggest the existence of immune regulatory mechanisms in islet milieu.
Puertas MC, Carrillo J, Pastor X, Ampudia RM, Alba A, Planas R, Pujol-Borrell R, Vives-Pi M, Verdaguer J.
Diabetes. 2007 Apr;56(4):940-9.PMID: 17395741 [PubMed - indexed for MEDLINE]Related articlesFree article
Two genetic loci regulate T cell-dependent islet inflammation and drive autoimmune diabetes pathogenesis.
Fox CJ, Paterson AD, Mortin-Toth SM, Danska JS.
Am J Hum Genet. 2000 Jul;67(1):67-81. Epub 2000 Jun 9.PMID: 10848492 [PubMed - indexed for MEDLINE]Related articlesFree article
Early autoimmune destruction of islet grafts is associated with a restricted repertoire of IGRP-specific CD8+ T cells in diabetic nonobese diabetic mice.
Wong CP, Li L, Frelinger JA, Tisch R.
J Immunol. 2006 Feb 1;176(3):1637-44.PMID: 16424193 [PubMed - indexed for MEDLINE]Related articlesFree article
Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice.
Tarbell KV, Petit L, Zuo X, Toy P, Luo X, Mqadmi A, Yang H, Suthanthiran M, Mojsov S, Steinman RM.
J Exp Med. 2007 Jan 22;204(1):191-201. Epub 2007 Jan 8.PMID: 17210729 [PubMed - indexed for MEDLINE]Related articlesFree article
CD4+CD25+ regulatory T cells control the progression from periinsulitis to destructive insulitis in murine autoimmune diabetes.
Ott PA, Anderson MR, Tary-Lehmann M, Lehmann PV.
Cell Immunol. 2005 May;235(1):1-11. Epub 2005 Aug 24.PMID: 16122720 [PubMed - indexed for MEDLINE]Related articles
Mechanisms of accelerated immune-mediated diabetes resulting from islet beta cell expression of a Fas ligand transgene.
Silva DG, Petrovsky N, Socha L, Slattery R, Gatenby P, Charlton B.
J Immunol. 2003 May 15;170(10):4996-5002.PMID: 12734343 [PubMed - indexed for MEDLINE]Related articlesFree article
IFN beta accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to beta cells in nondiabetes-prone mice.
Alba A, Puertas MC, Carrillo J, Planas R, Ampudia R, Pastor X, Bosch F, Pujol-Borrell R, Verdaguer J, Vives-Pi M.
J Immunol. 2004 Dec 1;173(11):6667-75.PMID: 15557158 [PubMed - indexed for MEDLINE]Related articlesFree article
Development of insulitis and diabetes in B cell-deficient NOD mice.
Yang M, Charlton B, Gautam AM.
J Autoimmun. 1997 Jun;10(3):257-60.PMID: 9218752 [PubMed - indexed for MEDLINE]Related articles
Anti-peripherin B lymphocytes are positively selected during diabetogenesis.
Carrillo J, Puertas MC, Planas R, Pastor X, Alba A, Stratmann T, Pujol-Borrell R, Ampudia RM, Vives-Pi M, Verdaguer J.
Mol Immunol. 2008 Jun;45(11):3152-62. Epub 2008 Apr 23.PMID: 18433871 [PubMed - indexed for MEDLINE]Related articles
Impaired activation of islet-reactive CD4 T cells in pancreatic lymph nodes of B cell-deficient nonobese diabetic mice.
Greeley SA, Moore DJ, Noorchashm H, Noto LE, Rostami SY, Schlachterman A, Song HK, Koeberlein B, Barker CF, Naji A.
J Immunol. 2001 Oct 15;167(8):4351-7.PMID: 11591759 [PubMed - indexed for MEDLINE]Related articlesFree article
Expression of genetically determined diabetes and insulitis in the nonobese diabetic (NOD) mouse at the level of bone marrow-derived cells. Transfer of diabetes and insulitis to nondiabetic (NOD X B10) F1 mice with bone marrow cells from NOD mice.
Wicker LS, Miller BJ, Chai A, Terada M, Mullen Y.
J Exp Med. 1988 Jun 1;167(6):1801-10.PMID: 3290380 [PubMed - indexed for MEDLINE]Related articlesFree article
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