PubMed

Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes.

Ritov VB, Menshikova EV, He J, Ferrell RE, Goodpaster BH, Kelley DE.

Diabetes. 2005 Jan;54(1):8-14.PMID: 15616005 [PubMed - indexed for MEDLINE]Related articlesFree article

Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes.

Kelley DE, He J, Menshikova EV, Ritov VB.

Diabetes. 2002 Oct;51(10):2944-50.PMID: 12351431 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of weight loss and physical activity on skeletal muscle mitochondrial function in obesity.

Menshikova EV, Ritov VB, Toledo FG, Ferrell RE, Goodpaster BH, Kelley DE.

Am J Physiol Endocrinol Metab. 2005 Apr;288(4):E818-25. Epub 2004 Dec 7.PMID: 15585590 [PubMed - indexed for MEDLINE]Related articlesFree article

Skeletal muscle mitochondrial functions, mitochondrial DNA copy numbers, and gene transcript profiles in type 2 diabetic and nondiabetic subjects at equal levels of low or high insulin and euglycemia.

Asmann YW, Stump CS, Short KR, Coenen-Schimke JM, Guo Z, Bigelow ML, Nair KS.

Diabetes. 2006 Dec;55(12):3309-19.PMID: 17130474 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondrial respiration is decreased in skeletal muscle of patients with type 2 diabetes.

Mogensen M, Sahlin K, Fernström M, Glintborg D, Vind BF, Beck-Nielsen H, Højlund K.

Diabetes. 2007 Jun;56(6):1592-9. Epub 2007 Mar 9.PMID: 17351150 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.

Morino K, Petersen KF, Dufour S, Befroy D, Frattini J, Shatzkes N, Neschen S, White MF, Bilz S, Sono S, Pypaert M, Shulman GI.

J Clin Invest. 2005 Dec;115(12):3587-93. Epub 2005 Nov 10.PMID: 16284649 [PubMed - indexed for MEDLINE]Related articlesFree article

Mitochondrial reactive oxygen species generation in obese non-diabetic and type 2 diabetic participants.

Abdul-Ghani MA, Jani R, Chavez A, Molina-Carrion M, Tripathy D, Defronzo RA.

Diabetologia. 2009 Apr;52(4):574-82. Epub 2009 Jan 30.PMID: 19183935 [PubMed - indexed for MEDLINE]Related articles

Muscle glucose transport and phosphorylation in type 2 diabetic, obese nondiabetic, and genetically predisposed individuals.

Pendergrass M, Bertoldo A, Bonadonna R, Nucci G, Mandarino L, Cobelli C, Defronzo RA.

Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E92-100. Epub 2006 Aug 8.PMID: 16896161 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance is associated with impaired nitric oxide synthase activity in skeletal muscle of type 2 diabetic subjects.

Kashyap SR, Roman LJ, Lamont J, Masters BS, Bajaj M, Suraamornkul S, Belfort R, Berria R, Kellogg DL Jr, Liu Y, DeFronzo RA.

J Clin Endocrinol Metab. 2005 Feb;90(2):1100-5. Epub 2004 Nov 23.PMID: 15562034 [PubMed - indexed for MEDLINE]Related articlesFree article

Skeletal muscle lipid content and oxidative enzyme activity in relation to muscle fiber type in type 2 diabetes and obesity.

He J, Watkins S, Kelley DE.

Diabetes. 2001 Apr;50(4):817-23.PMID: 11289047 [PubMed - indexed for MEDLINE]Related articlesFree article

Weight loss-induced plasticity of glucose transport and phosphorylation in the insulin resistance of obesity and type 2 diabetes.

Williams KV, Bertoldo A, Kinahan P, Cobelli C, Kelley DE.

Diabetes. 2003 Jul;52(7):1619-26.PMID: 12829624 [PubMed - indexed for MEDLINE]Related articlesFree article

Exercise training increases insulin-stimulated glucose disposal and GLUT4 (SLC2A4) protein content in patients with type 2 diabetes.

O'Gorman DJ, Karlsson HK, McQuaid S, Yousif O, Rahman Y, Gasparro D, Glund S, Chibalin AV, Zierath JR, Nolan JJ.

Diabetologia. 2006 Dec;49(12):2983-92. Epub 2006 Sep 26.PMID: 17019595 [PubMed - indexed for MEDLINE]Related articles

Changes induced by physical activity and weight loss in the morphology of intermyofibrillar mitochondria in obese men and women.

Toledo FG, Watkins S, Kelley DE.

J Clin Endocrinol Metab. 2006 Aug;91(8):3224-7. Epub 2006 May 9.PMID: 16684829 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced skeletal muscle uncoupling protein-3 content in prediabetic subjects and type 2 diabetic patients: restoration by rosiglitazone treatment.

Schrauwen P, Mensink M, Schaart G, Moonen-Kornips E, Sels JP, Blaak EE, Russell AP, Hesselink MK.

J Clin Endocrinol Metab. 2006 Apr;91(4):1520-5. Epub 2005 Dec 29.PMID: 16384852 [PubMed - indexed for MEDLINE]Related articlesFree article

Asian Indians have enhanced skeletal muscle mitochondrial capacity to produce ATP in association with severe insulin resistance.

Nair KS, Bigelow ML, Asmann YW, Chow LS, Coenen-Schimke JM, Klaus KA, Guo ZK, Sreekumar R, Irving BA.

Diabetes. 2008 May;57(5):1166-75. Epub 2008 Feb 19. Erratum in: Diabetes. 2009 Mar;58(3):770. PMID: 18285554 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of novel genes differentially expressed in omental fat of obese subjects and obese type 2 diabetic patients.

Corominola H, Conner LJ, Beavers LS, Gadski RA, Johnson D, Caro JF, Rafaeloff-Phail R.

Diabetes. 2001 Dec;50(12):2822-30.PMID: 11723066 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6.

Bach D, Naon D, Pich S, Soriano FX, Vega N, Rieusset J, Laville M, Guillet C, Boirie Y, Wallberg-Henriksson H, Manco M, Calvani M, Castagneto M, Palacín M, Mingrone G, Zierath JR, Vidal H, Zorzano A.

Diabetes. 2005 Sep;54(9):2685-93.PMID: 16123358 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of physical activity and weight loss on skeletal muscle mitochondria and relationship with glucose control in type 2 diabetes.

Toledo FG, Menshikova EV, Ritov VB, Azuma K, Radikova Z, DeLany J, Kelley DE.

Diabetes. 2007 Aug;56(8):2142-7. Epub 2007 May 29.PMID: 17536063 [PubMed - indexed for MEDLINE]Related articlesFree article

Obesity and type 2 diabetes impair insulin-induced suppression of glycogenolysis as well as gluconeogenesis.

Basu R, Chandramouli V, Dicke B, Landau B, Rizza R.

Diabetes. 2005 Jul;54(7):1942-8.PMID: 15983193 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced plasma adiponectin concentrations may contribute to impaired insulin activation of glycogen synthase in skeletal muscle of patients with type 2 diabetes.

Højlund K, Frystyk J, Levin K, Flyvbjerg A, Wojtaszewski JF, Beck-Nielsen H.

Diabetologia. 2006 Jun;49(6):1283-91. Epub 2006 Apr 12.PMID: 16609880 [PubMed - indexed for MEDLINE]Related articles