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Bench-to-bedside review: sepsis is a disease of the microcirculation.

Spronk PE, Zandstra DF, Ince C.

Crit Care. 2004 Dec;8(6):462-8. Epub 2004 Jun 16. Review.PMID: 15566617 [PubMed - indexed for MEDLINE]Related articlesFree article

Sepsis/septic shock: participation of the microcirculation: an abbreviated review.

Hinshaw LB.

Crit Care Med. 1996 Jun;24(6):1072-8. Review.PMID: 8681576 [PubMed - indexed for MEDLINE]Related articles

Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: relationship to hemodynamics, oxygen transport, and survival.

Trzeciak S, Dellinger RP, Parrillo JE, Guglielmi M, Bajaj J, Abate NL, Arnold RC, Colilla S, Zanotti S, Hollenberg SM; Microcirculatory Alterations in Resuscitation and Shock Investigators.

Ann Emerg Med. 2007 Jan;49(1):88-98, 98.e1-2. Epub 2006 Nov 7.PMID: 17095120 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of critical illness--classifying microcirculatory flow abnormalities in distributive shock.

Elbers PW, Ince C.

Crit Care. 2006;10(4):221. Review.PMID: 16879732 [PubMed - indexed for MEDLINE]Related articlesFree article

Microcirculatory oxygenation and shunting in sepsis and shock.

Ince C, Sinaasappel M.

Crit Care Med. 1999 Jul;27(7):1369-77. Review.PMID: 10446833 [PubMed - indexed for MEDLINE]Related articles

Disparity between skin perfusion and sublingual microcirculatory alterations in severe sepsis and septic shock: a prospective observational study.

Boerma EC, Kuiper MA, Kingma WP, Egbers PH, Gerritsen RT, Ince C.

Intensive Care Med. 2008 Jul;34(7):1294-8. Epub 2008 Mar 4.PMID: 18317733 [PubMed - indexed for MEDLINE]Related articlesFree article

Resuscitating the microcirculation in sepsis: the central role of nitric oxide, emerging concepts for novel therapies, and challenges for clinical trials.

Trzeciak S, Cinel I, Phillip Dellinger R, Shapiro NI, Arnold RC, Parrillo JE, Hollenberg SM; Microcirculatory Alterations in Resuscitation and Shock (MARS) Investigators.

Acad Emerg Med. 2008 May;15(5):399-413. Review.PMID: 18439194 [PubMed - indexed for MEDLINE]Related articlesFree article

The heterogeneity of the microcirculation in critical illness.

Klijn E, Den Uil CA, Bakker J, Ince C.

Clin Chest Med. 2008 Dec;29(4):643-54, viii. Review.PMID: 18954699 [PubMed - indexed for MEDLINE]Related articles

Shockingly complex: the difficult road to introducing new ideas to critical care.

Sibbald WJ.

Crit Care. 2004 Dec;8(6):419-21. Epub 2004 Oct 1.PMID: 15566606 [PubMed - indexed for MEDLINE]Related articlesFree article

The microcirculation is the motor of sepsis.

Ince C.

Crit Care. 2005;9 Suppl 4:S13-9. Epub 2005 Aug 25. Review.PMID: 16168069 [PubMed - indexed for MEDLINE]Related articles

Clinical manifestations of disordered microcirculatory perfusion in severe sepsis.

Trzeciak S, Rivers EP.

Crit Care. 2005;9 Suppl 4:S20-6. Epub 2005 Aug 25. Review.PMID: 16168070 [PubMed - indexed for MEDLINE]Related articles

Effect of increased cardiac output on hepatic and intestinal microcirculatory blood flow, oxygenation, and metabolism in hyperdynamic murine septic shock.

Albuszies G, Radermacher P, Vogt J, Wachter U, Weber S, Schoaff M, Georgieff M, Barth E.

Crit Care Med. 2005 Oct;33(10):2332-8.PMID: 16215389 [PubMed - indexed for MEDLINE]Related articles

Comparison of buccal microcirculation between septic and hemorrhagic shock.

Fang X, Tang W, Sun S, Huang L, Chang YT, Castillo C, Weil MH.

Crit Care Med. 2006 Dec;34(12 Suppl):S447-53.PMID: 17114976 [PubMed - indexed for MEDLINE]Related articles

[The therapeutic effects of fluid resuscitation in severe sepsis and septic shock]

Su Q, Wu LF, Fang Q, Yan J.

Zhonghua Wai Ke Za Zhi. 2006 Oct 1;44(19):1336-8. Chinese. PMID: 17217821 [PubMed - indexed for MEDLINE]Related articles

Heterogeneous microcirculation in the rat small intestine during hemorrhagic shock: quantification of the effects of hypertonic-hyperoncotic resuscitation.

Vajda K, Szabó A, Boros M.

Eur Surg Res. 2004 Nov-Dec;36(6):338-44.PMID: 15591741 [PubMed - indexed for MEDLINE]Related articles

Pharmacologic support of infants and children in septic shock.

Irazuzta J, Sullivan KJ, Garcia PC, Piva JP.

J Pediatr (Rio J). 2007 May;83(2 Suppl):S36-45. Review.PMID: 17530137 [PubMed - indexed for MEDLINE]Related articlesFree article

Bench-to-bedside review: microvascular dysfunction in sepsis--hemodynamics, oxygen transport, and nitric oxide.

Bateman RM, Sharpe MD, Ellis CG.

Crit Care. 2003 Oct;7(5):359-73. Epub 2003 Jul 28. Review.PMID: 12974969 [PubMed - indexed for MEDLINE]Related articlesFree article

Translating research to clinical practice: a 1-year experience with implementing early goal-directed therapy for septic shock in the emergency department.

Trzeciak S, Dellinger RP, Abate NL, Cowan RM, Stauss M, Kilgannon JH, Zanotti S, Parrillo JE.

Chest. 2006 Feb;129(2):225-32.PMID: 16478835 [PubMed - indexed for MEDLINE]Related articlesFree article

Microvascular resuscitation as a therapeutic goal in severe sepsis.

Bateman RM, Walley KR.

Crit Care. 2005;9 Suppl 4:S27-32. Epub 2005 Aug 25. Review.PMID: 16168071 [PubMed - indexed for MEDLINE]Related articles

Decreased red blood cell deformability and impaired oxygen utilization during human sepsis.

Powell RJ, Machiedo GW, Rush BF Jr.

Am Surg. 1993 Jan;59(1):65-8.PMID: 8480935 [PubMed - indexed for MEDLINE]Related articles