PubMed

Association studies of insulin receptor substrate 1 gene (IRS1) variants in type 2 diabetes samples enriched for family history and early age of onset.

Zeggini E, Parkinson J, Halford S, Owen KR, Frayling TM, Walker M, Hitman GA, Levy JC, Sampson MJ, Feskens EJ, Hattersley AT, McCarthy MI.

Diabetes. 2004 Dec;53(12):3319-22.PMID: 15561966 [PubMed - indexed for MEDLINE]Related articlesFree article

Association testing of common variants in the insulin receptor substrate-1 gene (IRS1) with type 2 diabetes.

Florez JC, Sjögren M, Agapakis CM, Burtt NP, Almgren P, Lindblad U, Berglund G, Tuomi T, Gaudet D, Daly MJ, Ardlie KG, Hirschhorn JN, Altshuler D, Groop L.

Diabetologia. 2007 Jun;50(6):1209-17. Epub 2007 Apr 19.PMID: 17443311 [PubMed - indexed for MEDLINE]Related articles

The role of insulin receptor substrate-1 gene (IRS1) in type 2 diabetes in Pima Indians.

Kovacs P, Hanson RL, Lee YH, Yang X, Kobes S, Permana PA, Bogardus C, Baier LJ.

Diabetes. 2003 Dec;52(12):3005-9.PMID: 14633864 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular scanning for mutations in the insulin receptor substrate-1 (IRS-1) gene in Mexican Americans with Type 2 diabetes mellitus.

Celi FS, Negri C, Tanner K, Raben N, De Pablo F, Rovira A, Pallardo LF, Martin-Vaquero P, Stern MP, Mitchell BD, Shuldiner AR.

Diabetes Metab Res Rev. 2000 Sep-Oct;16(5):370-7.PMID: 11025561 [PubMed - indexed for MEDLINE]Related articles

Large-scale studies of the association between variation at the TNF/LTA locus and susceptibility to type 2 diabetes.

Zeggini E, Groves CJ, Parkinson JR, Halford S, Owen KR, Frayling TM, Walker M, Hitman GA, Levy JC, O'Rahilly S, Hattersley AT, McCarthy MI.

Diabetologia. 2005 Oct;48(10):2013-7. Epub 2005 Aug 18.PMID: 16132956 [PubMed - indexed for MEDLINE]Related articles

AHSG tag single nucleotide polymorphisms associate with type 2 diabetes and dyslipidemia: studies of metabolic traits in 7,683 white Danish subjects.

Andersen G, Burgdorf KS, Sparsø T, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Diabetes. 2008 May;57(5):1427-32. Epub 2008 Mar 3.PMID: 18316360 [PubMed - indexed for MEDLINE]Related articlesFree article

Association testing in 9,000 people fails to confirm the association of the insulin receptor substrate-1 G972R polymorphism with type 2 diabetes.

Florez JC, Sjögren M, Burtt N, Orho-Melander M, Schayer S, Sun M, Almgren P, Lindblad U, Tuomi T, Gaudet D, Hudson TJ, Daly MJ, Ardlie KG, Hirschhorn JN, Altshuler D, Groop L.

Diabetes. 2004 Dec;53(12):3313-8.PMID: 15561965 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of the type 2 diabetes-associated single nucleotide polymorphisms in the genes IRS1, KCNJ11, and PPARG2 in type 1 diabetes.

Eftychi C, Howson JM, Barratt BJ, Vella A, Payne F, Smyth DJ, Twells RC, Walker NM, Rance HE, Tuomilehto-Wolf E, Tuomilehto J, Undlien DE, Rønningen KS, Guja C, Ionescu-Tîirgovişte C, Savage DA, Todd JA.

Diabetes. 2004 Mar;53(3):870-3.PMID: 14988278 [PubMed - indexed for MEDLINE]Related articlesFree article

Examining the relationships between the Pro12Ala variant in PPARG and Type 2 diabetes-related traits in UK samples.

Zeggini E, Parkinson JR, Halford S, Owen KR, Walker M, Hitman GA, Levy JC, Sampson MJ, Frayling TM, Hattersley AT, McCarthy MI.

Diabet Med. 2005 Dec;22(12):1696-700.PMID: 16401314 [PubMed - indexed for MEDLINE]Related articles

The insulin receptor substrate-1 Gly972Arg polymorphism is not associated with Type 2 diabetes mellitus in two population-based studies.

van Dam RM, Hoebee B, Seidell JC, Schaap MM, Blaak EE, Feskens EJ.

Diabet Med. 2004 Jul;21(7):752-8.PMID: 15209769 [PubMed - indexed for MEDLINE]Related articles

Gly972Arg variant in the insulin receptor substrate-1 gene and association with Type 2 diabetes: a meta-analysis of 27 studies.

Jellema A, Zeegers MP, Feskens EJ, Dagnelie PC, Mensink RP.

Diabetologia. 2003 Jul;46(7):990-5. Epub 2003 Jun 18.PMID: 12819898 [PubMed - indexed for MEDLINE]Related articles

No evidence of association of ENPP1 variants with type 2 diabetes or obesity in a study of 8,089 U.K. Caucasians.

Weedon MN, Shields B, Hitman G, Walker M, McCarthy MI, Hattersley AT, Frayling TM.

Diabetes. 2006 Nov;55(11):3175-9.PMID: 17065358 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variation in the LMNA gene (encoding lamin A/C) and type 2 diabetes: association analyses in 9,518 subjects.

Owen KR, Groves CJ, Hanson RL, Knowler WC, Shuldiner AR, Elbein SC, Mitchell BD, Froguel P, Ng MC, Chan JC, Jia W, Deloukas P, Hitman GA, Walker M, Frayling TM, Hattersley AT, Zeggini E, McCarthy MI.

Diabetes. 2007 Mar;56(3):879-83.PMID: 17327460 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevalence of variants in candidate genes for type 2 diabetes mellitus in The Netherlands: the Rotterdam study and the Hoorn study.

Hart LM, Stolk RP, Dekker JM, Nijpels G, Grobbee DE, Heine RJ, Maassen JA.

J Clin Endocrinol Metab. 1999 Mar;84(3):1002-6.PMID: 10084586 [PubMed - indexed for MEDLINE]Related articlesFree article

Association testing of variants in the hepatocyte nuclear factor 4alpha gene with risk of type 2 diabetes in 7,883 people.

Winckler W, Graham RR, de Bakker PI, Sun M, Almgren P, Tuomi T, Gaudet D, Hudson TJ, Ardlie KG, Daly MJ, Hirschhorn JN, Groop L, Altshuler D.

Diabetes. 2005 Mar;54(3):886-92.PMID: 15734869 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of the E23K polymorphism in the KCNJ11 gene with gestational diabetes mellitus.

Shaat N, Ekelund M, Lernmark A, Ivarsson S, Almgren P, Berntorp K, Groop L.

Diabetologia. 2005 Dec;48(12):2544-51. Epub 2005 Nov 17.PMID: 16320083 [PubMed - indexed for MEDLINE]Related articles

Association and haplotype analysis of the insulin-degrading enzyme (IDE) gene, a strong positional and biological candidate for type 2 diabetes susceptibility.

Groves CJ, Wiltshire S, Smedley D, Owen KR, Frayling TM, Walker M, Hitman GA, Levy JC, O'Rahilly S, Menzel S, Hattersley AT, McCarthy MI.

Diabetes. 2003 May;52(5):1300-5.PMID: 12716770 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variants of the hepatocyte nuclear factor-4alpha P2 promoter are associated with type 2 diabetes in the U.K. population.

Weedon MN, Owen KR, Shields B, Hitman G, Walker M, McCarthy MI, Love-Gregory LD, Permutt MA, Hattersley AT, Frayling TM.

Diabetes. 2004 Nov;53(11):3002-6.PMID: 15504983 [PubMed - indexed for MEDLINE]Related articlesFree article

Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects.

Grarup N, Urhammer SA, Ek J, Albrechtsen A, Glümer C, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Diabetologia. 2006 Sep;49(9):2097-104. Epub 2006 Jul 25.PMID: 16865358 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor alpha gene variation influences age of onset and progression of type 2 diabetes.

Flavell DM, Ireland H, Stephens JW, Hawe E, Acharya J, Mather H, Hurel SJ, Humphries SE.

Diabetes. 2005 Feb;54(2):582-6.PMID: 15677519 [PubMed - indexed for MEDLINE]Related articlesFree article