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    Results: 1 to 20 of 240

    1.

    Effects of polyol pathway hyperactivity on protein kinase C activity, nociceptive peptide expression, and neuronal structure in dorsal root ganglia in diabetic mice.

    Uehara K, Yamagishi S, Otsuki S, Chin S, Yagihashi S.

    Diabetes. 2004 Dec;53(12):3239-47.PMID: 15561956 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Mitogen-activated protein kinase p38 mediates reduced nerve conduction velocity in experimental diabetic neuropathy: interactions with aldose reductase.

    Price SA, Agthong S, Middlemas AB, Tomlinson DR.

    Diabetes. 2004 Jul;53(7):1851-6.PMID: 15220210 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Neuropathy in diabetic mice overexpressing human aldose reductase and effects of aldose reductase inhibitor.

    Yagihashi S, Yamagishi SI, Wada Ri R, Baba M, Hohman TC, Yabe-Nishimura C, Kokai Y.

    Brain. 2001 Dec;124(Pt 12):2448-58.PMID: 11701599 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Differential influence of increased polyol pathway on protein kinase C expressions between endoneurial and epineurial tissues in diabetic mice.

    Yamagishi S, Uehara K, Otsuki S, Yagihashi S.

    J Neurochem. 2003 Oct;87(2):497-507.PMID: 14511127 [PubMed - indexed for MEDLINE]Related articles

    5.

    Phosphorylation of c-Jun N-terminal kinase (JNK) in sensory neurones of diabetic rats, with possible effects on nerve conduction and neuropathic pain: prevention with an aldose reductase inhibitor.

    Middlemas AB, Agthong S, Tomlinson DR.

    Diabetologia. 2006 Mar;49(3):580-7. Epub 2006 Feb 3.PMID: 16456679 [PubMed - indexed for MEDLINE]Related articles

    6.

    Effect of the aldose reductase inhibitor fidarestat on experimental diabetic neuropathy in the rat.

    Kuzumoto Y, Kusunoki S, Kato N, Kihara M, Low PA.

    Diabetologia. 2006 Dec;49(12):3085-93. Epub 2006 Oct 25.PMID: 17063327 [PubMed - indexed for MEDLINE]Related articles

    7.

    Continuous inhibition of excessive polyol pathway flux in peripheral nerves by aldose reductase inhibitor fidarestat leads to improvement of diabetic neuropathy.

    Mizuno K, Kato N, Makino M, Suzuki T, Shindo M.

    J Diabetes Complications. 1999 May-Jun;13(3):141-50.PMID: 10509874 [PubMed - indexed for MEDLINE]Related articles

    8.

    Aldose reductase-deficient mice are protected from delayed motor nerve conduction velocity, increased c-Jun NH2-terminal kinase activation, depletion of reduced glutathione, increased superoxide accumulation, and DNA damage.

    Ho EC, Lam KS, Chen YS, Yip JC, Arvindakshan M, Yamagishi S, Yagihashi S, Oates PJ, Ellery CA, Chung SS, Chung SK.

    Diabetes. 2006 Jul;55(7):1946-53.PMID: 16804062 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Nerve growth factor (NGF) and diabetic neuropathy in the rat: morphological investigations of the sural nerve, dorsal root ganglion, and spinal cord.

    Unger JW, Klitzsch T, Pera S, Reiter R.

    Exp Neurol. 1998 Sep;153(1):23-34.PMID: 9743564 [PubMed - indexed for MEDLINE]Related articles

    10.

    Receptor for advanced glycation end products (RAGEs) and experimental diabetic neuropathy.

    Toth C, Rong LL, Yang C, Martinez J, Song F, Ramji N, Brussee V, Liu W, Durand J, Nguyen MD, Schmidt AM, Zochodne DW.

    Diabetes. 2008 Apr;57(4):1002-17. Epub 2007 Nov 26.PMID: 18039814 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Galactosemic neuropathy in transgenic mice for human aldose reductase.

    Yagihashi S, Yamagishi S, Wada R, Sugimoto K, Baba M, Wong HG, Fujimoto J, Nishimura C, Kokai Y.

    Diabetes. 1996 Jan;45(1):56-9.PMID: 8522060 [PubMed - indexed for MEDLINE]Related articles

    12.

    Effects of 15-month aldose reductase inhibition with fidarestat on the experimental diabetic neuropathy in rats.

    Kato N, Mizuno K, Makino M, Suzuki T, Yagihashi S.

    Diabetes Res Clin Pract. 2000 Oct;50(2):77-85.PMID: 10960717 [PubMed - indexed for MEDLINE]Related articles

    13.

    Protein kinase C isozyme expression in sciatic nerves and spinal cords of experimentally diabetic rats.

    Roberts RE, McLean WG.

    Brain Res. 1997 Apr 18;754(1-2):147-56.PMID: 9134970 [PubMed - indexed for MEDLINE]Related articles

    14.

    Administration of an aldose reductase inhibitor, ONO-2235, to streptozotocin-diabetic mice restores reductions of DRG neuronal attachment to extracellular matrix proteins in vitro.

    Sango K, Horie H, Inoue S.

    Neurosci Lett. 1999 Mar 26;263(2-3):157-60.PMID: 10213159 [PubMed - indexed for MEDLINE]Related articles

    15.

    Thirteen-month inhibition of aldose reductase by zenarestat prevents morphological abnormalities in the dorsal root ganglia of streptozotocin-induced diabetic rats.

    Shimoshige Y, Minoura K, Matsuoka N, Takakura S, Mutoh S, Kamijo M.

    Brain Res. 2009 Jan 9;1247:182-7. Epub 2008 Nov 1.PMID: 18992730 [PubMed - indexed for MEDLINE]Related articles

    16.

    Selective loss of calcitonin gene-related Peptide-expressing primary sensory neurons of the a-cell phenotype in early experimental diabetes.

    Jiang Y, Nyengaard JR, Zhang JS, Jakobsen J.

    Diabetes. 2004 Oct;53(10):2669-75.PMID: 15448099 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Effect of nerve growth factor on peptide neurons in dorsal root ganglia after taxol or cisplatin treatment and in diabetic (db/db) mice.

    Schmidt Y, Unger JW, Bartke I, Reiter R.

    Exp Neurol. 1995 Mar;132(1):16-23.PMID: 7536686 [PubMed - indexed for MEDLINE]Related articles

    18.

    Polyol pathway and protein kinase C activity of rat Schwannoma cells.

    Kamiya H, Nakamura J, Hamada Y, Nakashima E, Naruse K, Kato K, Yasuda Y, Hotta N.

    Diabetes Metab Res Rev. 2003 Mar-Apr;19(2):131-9.PMID: 12673781 [PubMed - indexed for MEDLINE]Related articles

    19.

    A protein kinase C-beta-selective inhibitor ameliorates neural dysfunction in streptozotocin-induced diabetic rats.

    Nakamura J, Kato K, Hamada Y, Nakayama M, Chaya S, Nakashima E, Naruse K, Kasuya Y, Mizubayashi R, Miwa K, Yasuda Y, Kamiya H, Ienaga K, Sakakibara F, Koh N, Hotta N.

    Diabetes. 1999 Oct;48(10):2090-5.PMID: 10512378 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Glucose-induced hyperproliferation of cultured rat aortic smooth muscle cells through polyol pathway hyperactivity.

    Nakamura J, Kasuya Y, Hamada Y, Nakashima E, Naruse K, Yasuda Y, Kato K, Hotta N.

    Diabetologia. 2001 Apr;44(4):480-7.PMID: 11357479 [PubMed - indexed for MEDLINE]Related articles

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