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    Results: 1 to 20 of 120

    1.

    Hyperglycemia regulates hypoxia-inducible factor-1alpha protein stability and function.

    Catrina SB, Okamoto K, Pereira T, Brismar K, Poellinger L.

    Diabetes. 2004 Dec;53(12):3226-32.PMID: 15561954 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.

    Baek JH, Mahon PC, Oh J, Kelly B, Krishnamachary B, Pearson M, Chan DA, Giaccia AJ, Semenza GL.

    Mol Cell. 2005 Feb 18;17(4):503-12.PMID: 15721254 [PubMed - indexed for MEDLINE]Related articles

    3.

    Stabilization of HIF-1alpha is critical to improve wound healing in diabetic mice.

    Botusan IR, Sunkari VG, Savu O, Catrina AI, Grünler J, Lindberg S, Pereira T, Ylä-Herttuala S, Poellinger L, Brismar K, Catrina SB.

    Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19426-31. Epub 2008 Dec 4.PMID: 19057015 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Activation of hypoxia-induced transcription in normoxia.

    Hägg M, Wennström S.

    Exp Cell Res. 2005 May 15;306(1):180-91. Epub 2005 Mar 19.PMID: 15878343 [PubMed - indexed for MEDLINE]Related articles

    5.

    Effects of prolyl hydroxylase inhibitors on adipogenesis and hypoxia inducible factor 1 alpha levels under normoxic conditions.

    Floyd ZE, Kilroy G, Wu X, Gimble JM.

    J Cell Biochem. 2007 Aug 15;101(6):1545-57.PMID: 17370314 [PubMed - indexed for MEDLINE]Related articles

    6.

    Fasudil-induced hypoxia-inducible factor-1alpha degradation disrupts a hypoxia-driven vascular endothelial growth factor autocrine mechanism in endothelial cells.

    Takata K, Morishige K, Takahashi T, Hashimoto K, Tsutsumi S, Yin L, Ohta T, Kawagoe J, Takahashi K, Kurachi H.

    Mol Cancer Ther. 2008 Jun;7(6):1551-61.PMID: 18566226 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1 alpha.

    Chan DA, Sutphin PD, Yen SE, Giaccia AJ.

    Mol Cell Biol. 2005 Aug;25(15):6415-26.PMID: 16024780 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Transforming growth factor beta1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression.

    McMahon S, Charbonneau M, Grandmont S, Richard DE, Dubois CM.

    J Biol Chem. 2006 Aug 25;281(34):24171-81. Epub 2006 Jun 30.PMID: 16815840 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Degradation of the hypoxia-inducible factor 1alpha: where does it happen?

    Pereira T, Zheng X, Poellinger L.

    Cell Cycle. 2006 Dec;5(23):2720-2. Epub 2006 Dec 1.PMID: 17172857 [PubMed - indexed for MEDLINE]Related articles

    10.

    Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.

    Carroll VA, Ashcroft M.

    Cancer Res. 2006 Jun 15;66(12):6264-70.PMID: 16778202 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2.

    Berchner-Pfannschmidt U, Yamac H, Trinidad B, Fandrey J.

    J Biol Chem. 2007 Jan 19;282(3):1788-96. Epub 2006 Oct 23.PMID: 17060326 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Regulation of hypoxia-inducible factor (HIF)-1 activity and expression of HIF hydroxylases in response to insulin-like growth factor I.

    Treins C, Giorgetti-Peraldi S, Murdaca J, Monthouël-Kartmann MN, Van Obberghen E.

    Mol Endocrinol. 2005 May;19(5):1304-17. Epub 2005 Feb 3.PMID: 15695372 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Does endogenous fatty acid metabolism allow cancer cells to sense hypoxia and mediate hypoxic vasodilatation? Characterization of a novel molecular connection between fatty acid synthase (FAS) and hypoxia-inducible factor-1alpha (HIF-1alpha)-related expression of vascular endothelial growth factor (VEGF) in cancer cells overexpressing her-2/neu oncogene.

    Menendez JA, Vellon L, Oza BP, Lupu R.

    J Cell Biochem. 2005 Apr 1;94(5):857-63.PMID: 15669079 [PubMed - indexed for MEDLINE]Related articles

    14.

    Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation.

    Martin F, Linden T, Katschinski DM, Oehme F, Flamme I, Mukhopadhyay CK, Eckhardt K, Tröger J, Barth S, Camenisch G, Wenger RH.

    Blood. 2005 Jun 15;105(12):4613-9. Epub 2005 Mar 1.PMID: 15741220 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    High glucose concentrations alter hypoxia-induced control of vascular smooth muscle cell growth via a HIF-1alpha-dependent pathway.

    Gao W, Ferguson G, Connell P, Walshe T, Murphy R, Birney YA, O'Brien C, Cahill PA.

    J Mol Cell Cardiol. 2007 Mar;42(3):609-19. Epub 2006 Dec 21.PMID: 17321542 [PubMed - indexed for MEDLINE]Related articles

    16.

    Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway.

    Tan C, de Noronha RG, Roecker AJ, Pyrzynska B, Khwaja F, Zhang Z, Zhang H, Teng Q, Nicholson AC, Giannakakou P, Zhou W, Olson JJ, Pereira MM, Nicolaou KC, Van Meir EG.

    Cancer Res. 2005 Jan 15;65(2):605-12.PMID: 15695405 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1alpha accumulation--implications for prolyl hydroxylase activity and iron.

    Callapina M, Zhou J, Schnitzer S, Metzen E, Lohr C, Deitmer JW, Brüne B.

    Exp Cell Res. 2005 May 15;306(1):274-84. Epub 2005 Mar 20.PMID: 15878351 [PubMed - indexed for MEDLINE]Related articles

    18.

    Effects of 12 metal ions on iron regulatory protein 1 (IRP-1) and hypoxia-inducible factor-1 alpha (HIF-1alpha) and HIF-regulated genes.

    Li Q, Chen H, Huang X, Costa M.

    Toxicol Appl Pharmacol. 2006 Jun 15;213(3):245-55. Epub 2006 Jan 4.PMID: 16386771 [PubMed - indexed for MEDLINE]Related articles

    19.

    Arrest-defective-1 protein, an acetyltransferase, does not alter stability of hypoxia-inducible factor (HIF)-1alpha and is not induced by hypoxia or HIF.

    Bilton R, Mazure N, Trottier E, Hattab M, Déry MA, Richard DE, Pouysségur J, Brahimi-Horn MC.

    J Biol Chem. 2005 Sep 2;280(35):31132-40. Epub 2005 Jul 1. Erratum in: J Biol Chem. 2006 Jun 2;281(22):15592. PMID: 15994306 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Hypoxia-inducible factor-1alpha stabilization in nonhypoxic conditions: role of oxidation and intracellular ascorbate depletion.

    Pagé EL, Chan DA, Giaccia AJ, Levine M, Richard DE.

    Mol Biol Cell. 2008 Jan;19(1):86-94. Epub 2007 Oct 17.PMID: 17942596 [PubMed - indexed for MEDLINE]Related articlesFree article

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