PubMed

Hyperlipidemia in concert with hyperglycemia stimulates the proliferation of macrophages in atherosclerotic lesions: potential role of glucose-oxidized LDL.

Lamharzi N, Renard CB, Kramer F, Pennathur S, Heinecke JW, Chait A, Bornfeldt KE.

Diabetes. 2004 Dec;53(12):3217-25.PMID: 15561953 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of hyperglycemia and hyperlipidemia on atherosclerosis in LDL receptor-deficient mice: establishment of a combined model and association with heat shock protein 65 immunity.

Keren P, George J, Shaish A, Levkovitz H, Janakovic Z, Afek A, Goldberg I, Kopolovic J, Keren G, Harats D.

Diabetes. 2000 Jun;49(6):1064-9.PMID: 10866061 [PubMed - indexed for MEDLINE]Related articlesFree article

Minimally oxidized LDL offsets the apoptotic effects of extensively oxidized LDL and free cholesterol in macrophages.

Boullier A, Li Y, Quehenberger O, Palinski W, Tabas I, Witztum JL, Miller YI.

Arterioscler Thromb Vasc Biol. 2006 May;26(5):1169-76. Epub 2006 Feb 16.PMID: 16484596 [PubMed - indexed for MEDLINE]Related articlesFree article

Blockade of endothelin receptors markedly reduces atherosclerosis in LDL receptor deficient mice: role of endothelin in macrophage foam cell formation.

Babaei S, Picard P, Ravandi A, Monge JC, Lee TC, Cernacek P, Stewart DJ.

Cardiovasc Res. 2000 Oct;48(1):158-67.PMID: 11033118 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophage proliferation in atherosclerosis.

Sakai M, Kobori S, Miyazaki A, Horiuchi S.

Curr Opin Lipidol. 2000 Oct;11(5):503-9. Review.PMID: 11048893 [PubMed - indexed for MEDLINE]Related articles

Effect of macrophage-derived apolipoprotein E on hyperlipidemia and atherosclerosis of LDLR-deficient mice.

Shi W, Wang X, Wong J, Hedrick CC, Wong H, Castellani LW, Lusis AJ.

Biochem Biophys Res Commun. 2004 Apr 23;317(1):223-9.PMID: 15047172 [PubMed - indexed for MEDLINE]Related articles

Addition of dietary fat to cholesterol in the diets of LDL receptor knockout mice: effects on plasma insulin, lipoproteins, and atherosclerosis.

Wu L, Vikramadithyan R, Yu S, Pau C, Hu Y, Goldberg IJ, Dansky HM.

J Lipid Res. 2006 Oct;47(10):2215-22. Epub 2006 Jul 13.PMID: 16840797 [PubMed - indexed for MEDLINE]Related articlesFree article

Do glucose and lipids exert independent effects on atherosclerotic lesion initiation or progression to advanced plaques?

Kanter JE, Johansson F, LeBoeuf RC, Bornfeldt KE.

Circ Res. 2007 Mar 30;100(6):769-81. Review.PMID: 17395883 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of macrophage responses to oxidized low-density lipoprotein and macrophage colony-stimulating factor (M-CSF or CSF-1).

Hamilton JA, Byrne R, Jessup W, Kanagasundaram V, Whitty G.

Biochem J. 2001 Feb 15;354(Pt 1):179-87.PMID: 11171093 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of class A scavenger receptor is enhanced by high glucose in vitro and under diabetic conditions in vivo: one mechanism for an increased rate of atherosclerosis in diabetes.

Fukuhara-Takaki K, Sakai M, Sakamoto Y, Takeya M, Horiuchi S.

J Biol Chem. 2005 Feb 4;280(5):3355-64. Epub 2004 Nov 19.PMID: 15556945 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 1 diabetes promotes disruption of advanced atherosclerotic lesions in LDL receptor-deficient mice.

Johansson F, Kramer F, Barnhart S, Kanter JE, Vaisar T, Merrill RD, Geng L, Oka K, Chan L, Chait A, Heinecke JW, Bornfeldt KE.

Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2082-7. Epub 2008 Feb 5.PMID: 18252823 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophage expression of peroxisome proliferator-activated receptor-alpha reduces atherosclerosis in low-density lipoprotein receptor-deficient mice.

Babaev VR, Ishiguro H, Ding L, Yancey PG, Dove DE, Kovacs WJ, Semenkovich CF, Fazio S, Linton MF.

Circulation. 2007 Sep 18;116(12):1404-12. Epub 2007 Aug 27.PMID: 17724261 [PubMed - indexed for MEDLINE]Related articlesFree article

RAGE mediates oxidized LDL-induced pro-inflammatory effects and atherosclerosis in non-diabetic LDL receptor-deficient mice.

Sun L, Ishida T, Yasuda T, Kojima Y, Honjo T, Yamamoto Y, Yamamoto H, Ishibashi S, Hirata K, Hayashi Y.

Cardiovasc Res. 2009 May 1;82(2):371-81. Epub 2009 Jan 28.PMID: 19176597 [PubMed - indexed for MEDLINE]Related articles

Phosphatidylinositol 3-kinase is involved in the induction of macrophage growth by oxidized low density lipoprotein.

Martens JS, Reiner NE, Herrera-Velit P, Steinbrecher UP.

J Biol Chem. 1998 Feb 27;273(9):4915-20.PMID: 9478935 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin II administration to atherosclerotic mice increases macrophage uptake of oxidized ldl: a possible role for interleukin-6.

Keidar S, Heinrich R, Kaplan M, Hayek T, Aviram M.

Arterioscler Thromb Vasc Biol. 2001 Sep;21(9):1464-9.PMID: 11557673 [PubMed - indexed for MEDLINE]Related articlesFree article

Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice.

Moore KJ, Kunjathoor VV, Koehn SL, Manning JJ, Tseng AA, Silver JM, McKee M, Freeman MW.

J Clin Invest. 2005 Aug;115(8):2192-201.PMID: 16075060 [PubMed - indexed for MEDLINE]Related articlesFree article

Aggressive very low-density lipoprotein (VLDL) and LDL lowering by gene transfer of the VLDL receptor combined with a low-fat diet regimen induces regression and reduces macrophage content in advanced atherosclerotic lesions in LDL receptor-deficient mice.

MacDougall ED, Kramer F, Polinsky P, Barnhart S, Askari B, Johansson F, Varon R, Rosenfeld ME, Oka K, Chan L, Schwartz SM, Bornfeldt KE.

Am J Pathol. 2006 Jun;168(6):2064-73.PMID: 16723719 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophage foam-cell formation in streptozotocin-induced diabetic mice: stimulatory effect of glucose.

Hayek T, Hussein K, Aviram M, Coleman R, Keidar S, Pavoltzky E, Kaplan M.

Atherosclerosis. 2005 Nov;183(1):25-33. Epub 2005 Apr 1.PMID: 16216589 [PubMed - indexed for MEDLINE]Related articles

Diabetes accelerates smooth muscle accumulation in lesions of atherosclerosis: lack of direct growth-promoting effects of high glucose levels.

Suzuki LA, Poot M, Gerrity RG, Bornfeldt KE.

Diabetes. 2001 Apr;50(4):851-60.PMID: 11289052 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophage ABCG1 deletion disrupts lipid homeostasis in alveolar macrophages and moderately influences atherosclerotic lesion development in LDL receptor-deficient mice.

Out R, Hoekstra M, Hildebrand RB, Kruit JK, Meurs I, Li Z, Kuipers F, Van Berkel TJ, Van Eck M.

Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2295-300. Epub 2006 Jul 20.PMID: 16857950 [PubMed - indexed for MEDLINE]Related articlesFree article