PubMed

Diet-induced glucose intolerance in mice with decreased beta-cell ATP-sensitive K+ channels.

Remedi MS, Koster JC, Markova K, Seino S, Miki T, Patton BL, McDaniel ML, Nichols CG.

Diabetes. 2004 Dec;53(12):3159-67.PMID: 15561946 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperinsulinism in mice with heterozygous loss of K(ATP) channels.

Remedi MS, Rocheleau JV, Tong A, Patton BL, McDaniel ML, Piston DW, Koster JC, Nichols CG.

Diabetologia. 2006 Oct;49(10):2368-78. Epub 2006 Aug 19.PMID: 16924481 [PubMed - indexed for MEDLINE]Related articles

Chronic antidiabetic sulfonylureas in vivo: reversible effects on mouse pancreatic beta-cells.

Remedi MS, Nichols CG.

PLoS Med. 2008 Oct 28;5(10):e206.PMID: 18959471 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose controls cytosolic Ca2+ and insulin secretion in mouse islets lacking adenosine triphosphate-sensitive K+ channels owing to a knockout of the pore-forming subunit Kir6.2.

Ravier MA, Nenquin M, Miki T, Seino S, Henquin JC.

Endocrinology. 2009 Jan;150(1):33-45. Epub 2008 Sep 11.PMID: 18787024 [PubMed - indexed for MEDLINE]Related articles

Gastric inhibitory polypeptide is the major insulinotropic factor in K(ATP) null mice.

Tsukiyama K, Yamada Y, Miyawaki K, Hamasaki A, Nagashima K, Hosokawa M, Fujimoto S, Takahashi A, Toyoda K, Toyokuni S, Oiso Y, Seino Y.

Eur J Endocrinol. 2004 Sep;151(3):407-12.PMID: 15362972 [PubMed - indexed for MEDLINE]Related articlesFree article

beta-cell hyperexcitability: from hyperinsulinism to diabetes.

Nichols CG, Koster JC, Remedi MS.

Diabetes Obes Metab. 2007 Nov;9 Suppl 2:81-8.PMID: 17919182 [PubMed - indexed for MEDLINE]Related articles

ATP-sensitive K+ channel signaling in glucokinase-deficient diabetes.

Remedi MS, Koster JC, Patton BL, Nichols CG.

Diabetes. 2005 Oct;54(10):2925-31.PMID: 16186394 [PubMed - indexed for MEDLINE]Related articlesFree article

K(ATP) channel knockout mice crossbred with transgenic mice expressing a dominant-negative form of human insulin receptor have glucose intolerance but not diabetes.

Kanezaki Y, Obata T, Matsushima R, Minami A, Yuasa T, Kishi K, Bando Y, Uehara H, Izumi K, Mitani T, Matsumoto M, Takeshita Y, Nakaya Y, Matsumoto T, Ebina Y.

Endocr J. 2004 Apr;51(2):133-44.PMID: 15118262 [PubMed - indexed for MEDLINE]Related articlesFree article

Sulfonylurea receptor knockout causes glucose intolerance in mice that is not alleviated by concomitant somatostatin subtype receptor 5 knockout.

Norman M, Moldovan S, Seghers V, Wang XP, DeMayo FJ, Brunicardi FC.

Ann Surg. 2002 Jun;235(6):767-74.PMID: 12035032 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 on insulin secretion and gut motility.

Miki T, Minami K, Shinozaki H, Matsumura K, Saraya A, Ikeda H, Yamada Y, Holst JJ, Seino S.

Diabetes. 2005 Apr;54(4):1056-63.PMID: 15793244 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperinsulinism induced by targeted suppression of beta cell KATP channels.

Koster JC, Remedi MS, Flagg TP, Johnson JD, Markova KP, Marshall BA, Nichols CG.

Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16992-7. Epub 2002 Dec 16.PMID: 12486236 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of ATP-insensitive KATP channels in pancreatic beta-cells underlies a spectrum of diabetic phenotypes.

Koster JC, Remedi MS, Masia R, Patton B, Tong A, Nichols CG.

Diabetes. 2006 Nov;55(11):2957-64.PMID: 17065331 [PubMed - indexed for MEDLINE]Related articlesFree article

Behavioral phenotyping of mice lacking the K ATP channel subunit Kir6.2.

Deacon RM, Brook RC, Meyer D, Haeckel O, Ashcroft FM, Miki T, Seino S, Liss B.

Physiol Behav. 2006 Apr 15;87(4):723-33. Epub 2006 Mar 10.PMID: 16530794 [PubMed - indexed for MEDLINE]Related articles

Glucose stimulates Ca2+ influx and insulin secretion in 2-week-old beta-cells lacking ATP-sensitive K+ channels.

Szollosi A, Nenquin M, Aguilar-Bryan L, Bryan J, Henquin JC.

J Biol Chem. 2007 Jan 19;282(3):1747-56. Epub 2006 Nov 30.PMID: 17138557 [PubMed - indexed for MEDLINE]Related articlesFree article

Overnight culture unmasks glucose-induced insulin secretion in mouse islets lacking ATP-sensitive K+ channels by improving the triggering Ca2+ signal.

Szollosi A, Nenquin M, Henquin JC.

J Biol Chem. 2007 May 18;282(20):14768-76. Epub 2007 Mar 27.PMID: 17389589 [PubMed - indexed for MEDLINE]Related articlesFree article

ATP-sensitive potassium channels participate in glucose uptake in skeletal muscle and adipose tissue.

Miki T, Minami K, Zhang L, Morita M, Gonoi T, Shiuchi T, Minokoshi Y, Renaud JM, Seino S.

Am J Physiol Endocrinol Metab. 2002 Dec;283(6):E1178-84. Epub 2002 Aug 13.PMID: 12388128 [PubMed - indexed for MEDLINE]Related articlesFree article

Spontaneous recovery from hyperglycemia by regeneration of pancreatic beta-cells in Kir6.2G132S transgenic mice.

Oyama K, Minami K, Ishizaki K, Fuse M, Miki T, Seino S.

Diabetes. 2006 Jul;55(7):1930-8.PMID: 16804060 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatocyte nuclear factor-4alpha is essential for glucose-stimulated insulin secretion by pancreatic beta-cells.

Miura A, Yamagata K, Kakei M, Hatakeyama H, Takahashi N, Fukui K, Nammo T, Yoneda K, Inoue Y, Sladek FM, Magnuson MA, Kasai H, Miyagawa J, Gonzalez FJ, Shimomura I.

J Biol Chem. 2006 Feb 24;281(8):5246-57. Epub 2005 Dec 23.PMID: 16377800 [PubMed - indexed for MEDLINE]Related articlesFree article

Membrane phosphoinositides control insulin secretion through their effects on ATP-sensitive K+ channel activity.

Lin CW, Yan F, Shimamura S, Barg S, Shyng SL.

Diabetes. 2005 Oct;54(10):2852-8.PMID: 16186385 [PubMed - indexed for MEDLINE]Related articlesFree article

KATP channel-deficient pancreatic beta-cells are streptozotocin resistant because of lower GLUT2 activity.

Xu J, Zhang L, Chou A, Allaby T, Bélanger G, Radziuk J, Jasmin BJ, Miki T, Seino S, Renaud JM.

Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E326-35. Epub 2007 Nov 27.PMID: 18042662 [PubMed - indexed for MEDLINE]Related articlesFree article