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    Results: 1 to 20 of 146

    1.

    Characterization of mice doubly transgenic for parathyroid hormone-related protein and murine placental lactogen: a novel role for placental lactogen in pancreatic beta-cell survival.

    Fujinaka Y, Sipula D, Garcia-Ocaña A, Vasavada RC.

    Diabetes. 2004 Dec;53(12):3120-30.PMID: 15561942 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Overexpression of parathyroid hormone-related protein inhibits pancreatic beta-cell death in vivo and in vitro.

    Cebrian A, García-Ocaña A, Takane KK, Sipula D, Stewart AF, Vasavada RC.

    Diabetes. 2002 Oct;51(10):3003-13.PMID: 12351440 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Transgenic overexpression of hepatocyte growth factor in the beta-cell markedly improves islet function and islet transplant outcomes in mice.

    García-Ocaña A, Vasavada RC, Cebrian A, Reddy V, Takane KK, López-Talavera JC, Stewart AF.

    Diabetes. 2001 Dec;50(12):2752-62.PMID: 11723058 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Targeted expression of placental lactogen in the beta cells of transgenic mice results in beta cell proliferation, islet mass augmentation, and hypoglycemia.

    Vasavada RC, Garcia-Ocaña A, Zawalich WS, Sorenson RL, Dann P, Syed M, Ogren L, Talamantes F, Stewart AF.

    J Biol Chem. 2000 May 19;275(20):15399-406.PMID: 10809775 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Progressive pancreatic islet hyperplasia in the islet-targeted, parathyroid hormone-related protein-overexpressing mouse.

    Porter SE, Sorenson RL, Dann P, Garcia-Ocana A, Stewart AF, Vasavada RC.

    Endocrinology. 1998 Sep;139(9):3743-51.PMID: 9724026 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Lactogens promote beta cell survival through JAK2/STAT5 activation and Bcl-XL upregulation.

    Fujinaka Y, Takane K, Yamashita H, Vasavada RC.

    J Biol Chem. 2007 Oct 19;282(42):30707-17. Epub 2007 Aug 29.PMID: 17728251 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Overexpression of parathyroid hormone-related protein in the pancreatic islets of transgenic mice causes islet hyperplasia, hyperinsulinemia, and hypoglycemia.

    Vasavada RC, Cavaliere C, D'Ercole AJ, Dann P, Burtis WJ, Madlener AL, Zawalich K, Zawalich W, Philbrick W, Stewart AF.

    J Biol Chem. 1996 Jan 12;271(2):1200-8.PMID: 8557651 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Protein kinase C-zeta activation markedly enhances beta-cell proliferation: an essential role in growth factor mediated beta-cell mitogenesis.

    Vasavada RC, Wang L, Fujinaka Y, Takane KK, Rosa TC, Mellado-Gil JM, Friedman PA, Garcia-Ocaña A.

    Diabetes. 2007 Nov;56(11):2732-43. Epub 2007 Aug 8.PMID: 17686945 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia.

    Garcia-Ocaña A, Takane KK, Syed MA, Philbrick WM, Vasavada RC, Stewart AF.

    J Biol Chem. 2000 Jan 14;275(2):1226-32.PMID: 10625667 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Overexpression of c-Myc in beta-cells of transgenic mice causes proliferation and apoptosis, downregulation of insulin gene expression, and diabetes.

    Laybutt DR, Weir GC, Kaneto H, Lebet J, Palmiter RD, Sharma A, Bonner-Weir S.

    Diabetes. 2002 Jun;51(6):1793-804.PMID: 12031967 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Evaluation of beta-cell replication in mice transgenic for hepatocyte growth factor and placental lactogen: comprehensive characterization of the G1/S regulatory proteins reveals unique involvement of p21cip.

    Cozar-Castellano I, Weinstock M, Haught M, Velázquez-Garcia S, Sipula D, Stewart AF.

    Diabetes. 2006 Jan;55(1):70-7.PMID: 16380478 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Glucose intolerance and reduced islet blood flow in transgenic mice expressing the FRK tyrosine kinase under the control of the rat insulin promoter.

    Annerén C, Welsh M, Jansson L.

    Am J Physiol Endocrinol Metab. 2007 Apr;292(4):E1183-90. Epub 2006 Dec 19.PMID: 17179392 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Destruction of pancreatic beta-cells by transgenic induction of prostaglandin E2 in the islets.

    Oshima H, Taketo MM, Oshima M.

    J Biol Chem. 2006 Sep 29;281(39):29330-6. Epub 2006 Jul 27.PMID: 16873378 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    In vivo proliferation of differentiated pancreatic islet beta cells in transgenic mice expressing mutated cyclin-dependent kinase 4.

    Hino S, Yamaoka T, Yamashita Y, Yamada T, Hata J, Itakura M.

    Diabetologia. 2004 Oct;47(10):1819-30. Epub 2004 Oct 6.PMID: 15480536 [PubMed - indexed for MEDLINE]Related articles

    15.

    Analysis of rat insulin II promoter-ghrelin transgenic mice and rat glucagon promoter-ghrelin transgenic mice.

    Iwakura H, Hosoda K, Son C, Fujikura J, Tomita T, Noguchi M, Ariyasu H, Takaya K, Masuzaki H, Ogawa Y, Hayashi T, Inoue G, Akamizu T, Hosoda H, Kojima M, Itoh H, Toyokuni S, Kangawa K, Nakao K.

    J Biol Chem. 2005 Apr 15;280(15):15247-56. Epub 2005 Feb 8.PMID: 15701644 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Overexpression of a dominant negative GIP receptor in transgenic mice results in disturbed postnatal pancreatic islet and beta-cell development.

    Herbach N, Goeke B, Schneider M, Hermanns W, Wolf E, Wanke R.

    Regul Pept. 2005 Feb 15;125(1-3):103-17.PMID: 15582721 [PubMed - indexed for MEDLINE]Related articles

    17.

    Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression.

    Kim SJ, Winter K, Nian C, Tsuneoka M, Koda Y, McIntosh CH.

    J Biol Chem. 2005 Jun 10;280(23):22297-307. Epub 2005 Apr 6.PMID: 15817464 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Overexpression of PACAP in transgenic mouse pancreatic beta-cells enhances insulin secretion and ameliorates streptozotocin-induced diabetes.

    Yamamoto K, Hashimoto H, Tomimoto S, Shintani N, Miyazaki J, Tashiro F, Aihara H, Nammo T, Li M, Yamagata K, Miyagawa J, Matsuzawa Y, Kawabata Y, Fukuyama Y, Koga K, Mori W, Tanaka K, Matsuda T, Baba A.

    Diabetes. 2003 May;52(5):1155-62.PMID: 12716746 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Constitutive expression of placental lactogen in pancreatic beta cells: effects on cell morphology, growth, and gene expression.

    Fleenor D, Petryk A, Driscoll P, Freemark M.

    Pediatr Res. 2000 Jan;47(1):136-42.PMID: 10625094 [PubMed - indexed for MEDLINE]Related articles

    20.

    A peptide-major histocompatibility complex II chimera favors survival of pancreatic beta-islets grafted in type 1 diabetic mice.

    Casares S, Lin M, Zhang N, Teijaro JR, Stoica C, McEvoy R, Farber DL, Bona C, Brumeanu TD.

    Transplantation. 2008 Jun 27;85(12):1717-25.PMID: 18580462 [PubMed - indexed for MEDLINE]Related articles

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