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    Results: 1 to 20 of 128

    1.

    G-protein signaling participates in the development of diabetic cardiomyopathy.

    Harris IS, Treskov I, Rowley MW, Heximer S, Kaltenbronn K, Finck BN, Gross RW, Kelly DP, Blumer KJ, Muslin AJ.

    Diabetes. 2004 Dec;53(12):3082-90.PMID: 15561937 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Cardiac overexpression of hormone-sensitive lipase inhibits myocardial steatosis and fibrosis in streptozotocin diabetic mice.

    Ueno M, Suzuki J, Zenimaru Y, Takahashi S, Koizumi T, Noriki S, Yamaguchi O, Otsu K, Shen WJ, Kraemer FB, Miyamori I.

    Am J Physiol Endocrinol Metab. 2008 Jun;294(6):E1109-18. Epub 2008 Apr 15.PMID: 18413675 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Regulator of G-protein signaling subtype 4 mediates antihypertrophic effect of locally secreted natriuretic peptides in the heart.

    Tokudome T, Kishimoto I, Horio T, Arai Y, Schwenke DO, Hino J, Okano I, Kawano Y, Kohno M, Miyazato M, Nakao K, Kangawa K.

    Circulation. 2008 May 6;117(18):2329-39. Epub 2008 Apr 28.PMID: 18443239 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    The role of the peroxisome proliferator-activated receptor alpha pathway in pathological remodeling of the diabetic heart.

    Finck BN.

    Curr Opin Clin Nutr Metab Care. 2004 Jul;7(4):391-6. Review.PMID: 15192440 [PubMed - indexed for MEDLINE]Related articles

    5.

    Overexpression of Gsalpha compensates for myocyte loss in diabetic cardiomyopathy.

    Malhotra A, Kang BP, Vashistha H, Yadav VS, Meggs LG.

    Can J Physiol Pharmacol. 2008 Mar;86(3):122-30.PMID: 18418439 [PubMed - indexed for MEDLINE]Related articles

    6.

    Gene deletion of the kinin receptor B1 attenuates cardiac inflammation and fibrosis during the development of experimental diabetic cardiomyopathy.

    Westermann D, Walther T, Savvatis K, Escher F, Sobirey M, Riad A, Bader M, Schultheiss HP, Tschöpe C.

    Diabetes. 2009 Jun;58(6):1373-81. Epub 2009 Mar 10.PMID: 19276445 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    PPAR-alpha activation required for decreased glucose uptake and increased susceptibility to injury during ischemia.

    Panagia M, Gibbons GF, Radda GK, Clarke K.

    Am J Physiol Heart Circ Physiol. 2005 Jun;288(6):H2677-83. Epub 2005 Jan 21.PMID: 15665064 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.

    Finck BN, Han X, Courtois M, Aimond F, Nerbonne JM, Kovacs A, Gross RW, Kelly DP.

    Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1226-31. Epub 2003 Jan 27.PMID: 12552126 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Insulin-resistant heart exhibits a mitochondrial biogenic response driven by the peroxisome proliferator-activated receptor-alpha/PGC-1alpha gene regulatory pathway.

    Duncan JG, Fong JL, Medeiros DM, Finck BN, Kelly DP.

    Circulation. 2007 Feb 20;115(7):909-17. Epub 2007 Jan 29.PMID: 17261654 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Low- and high-level transgenic expression of beta2-adrenergic receptors differentially affect cardiac hypertrophy and function in Galphaq-overexpressing mice.

    Dorn GW 2nd, Tepe NM, Lorenz JN, Koch WJ, Liggett SB.

    Proc Natl Acad Sci U S A. 1999 May 25;96(11):6400-5.PMID: 10339599 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus.

    Finck BN, Lehman JJ, Leone TC, Welch MJ, Bennett MJ, Kovacs A, Han X, Gross RW, Kozak R, Lopaschuk GD, Kelly DP.

    J Clin Invest. 2002 Jan;109(1):121-30.PMID: 11781357 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    RGS4 reduces contractile dysfunction and hypertrophic gene induction in Galpha q overexpressing mice.

    Rogers JH, Tsirka A, Kovacs A, Blumer KJ, Dorn GW 2nd, Muslin AJ.

    J Mol Cell Cardiol. 2001 Feb;33(2):209-18.PMID: 11162127 [PubMed - indexed for MEDLINE]Related articles

    13.

    Inactivation of 14-3-3 protein exacerbates cardiac hypertrophy and fibrosis through enhanced expression of protein kinase C beta 2 in experimental diabetes.

    Gurusamy N, Watanabe K, Ma M, Zhang S, Muslin AJ, Kodama M, Aizawa Y.

    Biol Pharm Bull. 2005 Jun;28(6):957-62.PMID: 15930726 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Inhibition of PPAR-alpha activity in mice with cardiac-restricted expression of tumor necrosis factor: potential role of TGF-beta/Smad3.

    Sekiguchi K, Tian Q, Ishiyama M, Burchfield J, Gao F, Mann DL, Barger PM.

    Am J Physiol Heart Circ Physiol. 2007 Mar;292(3):H1443-51. Epub 2006 Nov 10.PMID: 17098824 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    CD36 deficiency rescues lipotoxic cardiomyopathy.

    Yang J, Sambandam N, Han X, Gross RW, Courtois M, Kovacs A, Febbraio M, Finck BN, Kelly DP.

    Circ Res. 2007 Apr 27;100(8):1208-17. Epub 2007 Mar 15.PMID: 17363697 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Alterations in 5-HT2A receptor signaling in male and female transgenic rats over-expressing either Gq or RGS-insensitive Gq protein.

    Shi J, Damjanoska KJ, Zemaitaitis B, Garcia F, Carrasco G, Sullivan NR, She Y, Young KH, Battaglia G, Van De kar LD, Howland DS, Muma NA.

    Neuropharmacology. 2006 Sep;51(3):524-35.PMID: 16769091 [PubMed - indexed for MEDLINE]Related articles

    17.

    Diacylglycerol kinase zeta inhibits myocardial atrophy and restores cardiac dysfunction in streptozotocin-induced diabetes mellitus.

    Bilim O, Takeishi Y, Kitahara T, Arimoto T, Niizeki T, Sasaki T, Goto K, Kubota I.

    Cardiovasc Diabetol. 2008 Feb 4;7:2.PMID: 18241357 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Metallothionein suppresses angiotensin II-induced nicotinamide adenine dinucleotide phosphate oxidase activation, nitrosative stress, apoptosis, and pathological remodeling in the diabetic heart.

    Zhou G, Li X, Hein DW, Xiang X, Marshall JP, Prabhu SD, Cai L.

    J Am Coll Cardiol. 2008 Aug 19;52(8):655-66.PMID: 18702970 [PubMed - indexed for MEDLINE]Related articles

    19.

    Myocardial overexpression of adenine nucleotide translocase 1 ameliorates diabetic cardiomyopathy in mice.

    Wang Y, Ebermann L, Sterner-Kock A, Wika S, Schultheiss HP, Dörner A, Walther T.

    Exp Physiol. 2009 Feb;94(2):220-7. Epub 2008 Oct 22.PMID: 18945756 [PubMed - indexed for MEDLINE]Related articles

    20.

    Diacylglycerol kinase zeta rescues G alpha q-induced heart failure in transgenic mice.

    Niizeki T, Takeishi Y, Kitahara T, Arimoto T, Koyama Y, Goto K, Mende U, Kubota I.

    Circ J. 2008 Feb;72(2):309-17.PMID: 18219172 [PubMed - indexed for MEDLINE]Related articlesFree article

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