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    Results: 1 to 20 of 262

    1.

    Hepatic PTP-1B expression regulates the assembly and secretion of apolipoprotein B-containing lipoproteins: evidence from protein tyrosine phosphatase-1B overexpression, knockout, and RNAi studies.

    Qiu W, Avramoglu RK, Dubé N, Chong TM, Naples M, Au C, Sidiropoulos KG, Lewis GF, Cohn JS, Tremblay ML, Adeli K.

    Diabetes. 2004 Dec;53(12):3057-66.PMID: 15561934 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance.

    Taghibiglou C, Rashid-Kolvear F, Van Iderstine SC, Le-Tien H, Fantus IG, Lewis GF, Adeli K.

    J Biol Chem. 2002 Jan 4;277(1):793-803. Epub 2001 Oct 11.PMID: 11598116 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Inflammatory NF-kappaB activation promotes hepatic apolipoprotein B100 secretion: evidence for a link between hepatic inflammation and lipoprotein production.

    Tsai J, Zhang R, Qiu W, Su Q, Naples M, Adeli K.

    Am J Physiol Gastrointest Liver Physiol. 2009 Jun;296(6):G1287-98. Epub 2009 Apr 2.PMID: 19342510 [PubMed - indexed for MEDLINE]Related articles

    4.

    Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B-containing lipoproteins.

    Qiu W, Federico L, Naples M, Avramoglu RK, Meshkani R, Zhang J, Tsai J, Hussain M, Dai K, Iqbal J, Kontos CD, Horie Y, Suzuki A, Adeli K.

    Hepatology. 2008 Dec;48(6):1799-809.PMID: 19026012 [PubMed - indexed for MEDLINE]Related articles

    5.

    LXRalpha activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins.

    Basciano H, Miller A, Baker C, Naples M, Adeli K.

    Am J Physiol Gastrointest Liver Physiol. 2009 Aug;297(2):G323-32. Epub 2009 Jun 4.PMID: 19497957 [PubMed - indexed for MEDLINE]Related articles

    6.

    Intestinal insulin resistance and aberrant production of apolipoprotein B48 lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia: evidence for activation of protein tyrosine phosphatase-1B, extracellular signal-related kinase, and sterol regulatory element-binding protein-1c in the fructose-fed hamster intestine.

    Federico LM, Naples M, Taylor D, Adeli K.

    Diabetes. 2006 May;55(5):1316-26.PMID: 16644688 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Protein tyrosine phosphatase 1B attenuates growth hormone-mediated JAK2-STAT signaling.

    Gu F, Dubé N, Kim JW, Cheng A, Ibarra-Sanchez Mde J, Tremblay ML, Boisclair YR.

    Mol Cell Biol. 2003 Jun;23(11):3753-62.PMID: 12748279 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Effects of adenovirus-mediated liver-selective overexpression of protein tyrosine phosphatase-1b on insulin sensitivity in vivo.

    Wang J, Cheung AT, Kolls JK, Starks WW, Martinez-Hernandez A, Dietzen D, Bryer-Ash M.

    Diabetes Obes Metab. 2001 Oct;3(5):367-80.PMID: 11703427 [PubMed - indexed for MEDLINE]Related articles

    9.

    Treatment with atorvastatin ameliorates hepatic very-low-density lipoprotein overproduction in an animal model of insulin resistance, the fructose-fed Syrian golden hamster: evidence that reduced hypertriglyceridemia is accompanied by improved hepatic insulin sensitivity.

    Mangaloglu L, Cheung RC, Van Iderstine SC, Taghibiglou C, Pontrelli L, Adeli K.

    Metabolism. 2002 Apr;51(4):409-18.PMID: 11912545 [PubMed - indexed for MEDLINE]Related articles

    10.

    Ameliorated hepatic insulin resistance is associated with normalization of microsomal triglyceride transfer protein expression and reduction in very low density lipoprotein assembly and secretion in the fructose-fed hamster.

    Carpentier A, Taghibiglou C, Leung N, Szeto L, Van Iderstine SC, Uffelman KD, Buckingham R, Adeli K, Lewis GF.

    J Biol Chem. 2002 Aug 9;277(32):28795-802. Epub 2002 Jun 4.PMID: 12048212 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Tumor necrosis factor-alpha directly stimulates the overproduction of hepatic apolipoprotein B100-containing VLDL via impairment of hepatic insulin signaling.

    Qin B, Anderson RA, Adeli K.

    Am J Physiol Gastrointest Liver Physiol. 2008 May;294(5):G1120-9. Epub 2008 Mar 27.PMID: 18372392 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Developmental switch from prolonged insulin action to increased insulin sensitivity in protein tyrosine phosphatase 1B-deficient hepatocytes.

    Gonzalez-Rodriguez A, Clampit JE, Escribano O, Benito M, Rondinone CM, Valverde AM.

    Endocrinology. 2007 Feb;148(2):594-608. Epub 2006 Oct 26.PMID: 17068137 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene.

    Elchebly M, Payette P, Michaliszyn E, Cromlish W, Collins S, Loy AL, Normandin D, Cheng A, Himms-Hagen J, Chan CC, Ramachandran C, Gresser MJ, Tremblay ML, Kennedy BP.

    Science. 1999 Mar 5;283(5407):1544-8.PMID: 10066179 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Identification of the tyrosine phosphatase PTP-MEG2 as an antagonist of hepatic insulin signaling.

    Cho CY, Koo SH, Wang Y, Callaway S, Hedrick S, Mak PA, Orth AP, Peters EC, Saez E, Montminy M, Schultz PG, Chanda SK.

    Cell Metab. 2006 May;3(5):367-78.PMID: 16679294 [PubMed - indexed for MEDLINE]Related articles

    15.

    Protein tyrosine phosphatase-1B dephosphorylation of the insulin receptor occurs in a perinuclear endosome compartment in human embryonic kidney 293 cells.

    Romsicki Y, Reece M, Gauthier JY, Asante-Appiah E, Kennedy BP.

    J Biol Chem. 2004 Mar 26;279(13):12868-75. Epub 2004 Jan 13.PMID: 14722096 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice.

    Klaman LD, Boss O, Peroni OD, Kim JK, Martino JL, Zabolotny JM, Moghal N, Lubkin M, Kim YB, Sharpe AH, Stricker-Krongrad A, Shulman GI, Neel BG, Kahn BB.

    Mol Cell Biol. 2000 Aug;20(15):5479-89.PMID: 10891488 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Effect of rosuvastatin on hepatic production of apolipoprotein B-containing lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia.

    Chong T, Naples M, Federico L, Taylor D, Smith GJ, Cheung RC, Adeli K.

    Atherosclerosis. 2006 Mar;185(1):21-31. Epub 2005 Jul 5.PMID: 16002078 [PubMed - indexed for MEDLINE]Related articles

    18.

    The low density lipoprotein receptor prevents secretion of dense apoB100-containing lipoproteins from the liver.

    Larsson SL, Skogsberg J, Björkegren J.

    J Biol Chem. 2004 Jan 9;279(2):831-6. Epub 2003 Oct 28.PMID: 14583618 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model.

    Taghibiglou C, Carpentier A, Van Iderstine SC, Chen B, Rudy D, Aiton A, Lewis GF, Adeli K.

    J Biol Chem. 2000 Mar 24;275(12):8416-25. Erratum in: J Biol Chem 2001 Jun 8;276(23):20804. PMID: 10722675 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    [The role of protein tyrosine phosphatase (PTP-1B) in insulin resistance]

    Boduła A, Wdowczyk M, Adamiec R.

    Postepy Hig Med Dosw (Online). 2005 May 16;59:203-7. Review. Polish. PMID: 15928604 [PubMed - indexed for MEDLINE]Related articlesFree article

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