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    Results: 1 to 20 of 178

    1.

    Effect of PPAR-gamma activation and inhibition on glucose-stimulated insulin release in INS-1e cells.

    Santini E, Fallahi P, Ferrari SM, Masoni A, Antonelli A, Ferrannini E.

    Diabetes. 2004 Dec;53 Suppl 3:S79-83.PMID: 15561927 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Peroxisome proliferator-activated receptor alpha (PPARalpha) potentiates, whereas PPARgamma attenuates, glucose-stimulated insulin secretion in pancreatic beta-cells.

    Ravnskjaer K, Boergesen M, Rubi B, Larsen JK, Nielsen T, Fridriksson J, Maechler P, Mandrup S.

    Endocrinology. 2005 Aug;146(8):3266-76. Epub 2005 May 5.PMID: 15878969 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Selective modification of pyruvate dehydrogenase kinase isoform expression in rat pancreatic islets elicited by starvation and activation of peroxisome proliferator-activated receptor-alpha: implications for glucose-stimulated insulin secretion.

    Sugden MC, Bulmer K, Augustine D, Holness MJ.

    Diabetes. 2001 Dec;50(12):2729-36.PMID: 11723055 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Troglitazone ameliorates lipotoxicity in the beta cell line INS-1 expressing PPAR gamma.

    Kawai T, Hirose H, Seto Y, Fujita H, Fujita H, Ukeda K, Saruta T.

    Diabetes Res Clin Pract. 2002 May;56(2):83-92.PMID: 11891015 [PubMed - indexed for MEDLINE]Related articles

    5.

    Effects of PPAR-gamma knock-down and hyperglycemia on insulin signaling in vascular smooth muscle cells from hypertensive rats.

    Pandey NR, Benkirane K, Amiri F, Schiffrin EL.

    J Cardiovasc Pharmacol. 2007 Jun;49(6):346-54.PMID: 17577098 [PubMed - indexed for MEDLINE]Related articles

    6.

    Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion.

    Hohmeier HE, Mulder H, Chen G, Henkel-Rieger R, Prentki M, Newgard CB.

    Diabetes. 2000 Mar;49(3):424-30.PMID: 10868964 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Effects of ghrelin and other neuropeptides (CART, MCH, orexin A and B, and GLP-1) on the release of insulin from isolated rat islets.

    Colombo M, Gregersen S, Xiao J, Hermansen K.

    Pancreas. 2003 Aug;27(2):161-6.PMID: 12883265 [PubMed - indexed for MEDLINE]Related articles

    8.

    Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARgamma2 in the modulation of insulin secretion.

    Lupi R, Del Guerra S, Marselli L, Bugliani M, Boggi U, Mosca F, Marchetti P, Del Prato S.

    Am J Physiol Endocrinol Metab. 2004 Apr;286(4):E560-7. Epub 2003 Nov 18.PMID: 14625208 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Chronic palmitate exposure inhibits AMPKalpha and decreases glucose-stimulated insulin secretion from beta-cells: modulation by fenofibrate.

    Sun Y, Ren M, Gao GQ, Gong B, Xin W, Guo H, Zhang XJ, Gao L, Zhao JJ.

    Acta Pharmacol Sin. 2008 Apr;29(4):443-50.PMID: 18358090 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Prolonged elevation of plasma free fatty acids desensitizes the insulin secretory response to glucose in vivo in rats.

    Mason TM, Goh T, Tchipashvili V, Sandhu H, Gupta N, Lewis GF, Giacca A.

    Diabetes. 1999 Mar;48(3):524-30.PMID: 10078552 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion.

    Herrero L, Rubí B, Sebastián D, Serra D, Asins G, Maechler P, Prentki M, Hegardt FG.

    Diabetes. 2005 Feb;54(2):462-71.PMID: 15677504 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-gamma inhibition.

    Patanè G, Anello M, Piro S, Vigneri R, Purrello F, Rabuazzo AM.

    Diabetes. 2002 Sep;51(9):2749-56.PMID: 12196468 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Different secretory response of pancreatic islets and insulin secreting cell lines INS-1 and INS-1E to osmotic stimuli.

    Orecná M, Hafko R, Bacová Z, Podskocová J, Chorvát D Jr, Strbák V.

    Physiol Res. 2008;57(6):935-45. Epub 2007 Nov 30.PMID: 18052676 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Role and mechanism of rosiglitazone on the impairment of insulin secretion induced by free fatty acids on isolated rat islets.

    Tian JY, Li G, Gu YY, Zhang HL, Zhou WZ, Wang X, Zhu HD, Luo TH, Luo M.

    Chin Med J (Engl). 2006 Apr 5;119(7):574-80.PMID: 16620699 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Effects of peroxisome proliferator-activated receptor (PPAR)-alpha and PPAR-gamma agonists on glucose and lipid metabolism in patients with type 2 diabetes mellitus.

    Bajaj M, Suraamornkul S, Hardies LJ, Glass L, Musi N, DeFronzo RA.

    Diabetologia. 2007 Aug;50(8):1723-31. Epub 2007 May 23.PMID: 17520238 [PubMed - indexed for MEDLINE]Related articles

    16.

    Inhibition of mitochondrial Na+-Ca2+ exchanger increases mitochondrial metabolism and potentiates glucose-stimulated insulin secretion in rat pancreatic islets.

    Lee B, Miles PD, Vargas L, Luan P, Glasco S, Kushnareva Y, Kornbrust ES, Grako KA, Wollheim CB, Maechler P, Olefsky JM, Anderson CM.

    Diabetes. 2003 Apr;52(4):965-73.PMID: 12663468 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Effects of glucose, forskolin and tolbutamide on membrane potential and insulin secretion in the insulin-secreting cell line INS-1.

    Ullrich S, Abel KB, Lehr S, Greger R.

    Pflugers Arch. 1996 Aug;432(4):630-6.PMID: 8764963 [PubMed - indexed for MEDLINE]Related articles

    18.

    Peroxisome proliferator-activated receptor-alpha activation during pregnancy attenuates glucose-stimulated insulin hypersecretion in vivo by increasing insulin sensitivity, without impairing pregnancy-induced increases in beta-cell glucose sensing and responsiveness.

    Sugden MC, Greenwood GK, Smith ND, Holness MJ.

    Endocrinology. 2003 Jan;144(1):146-53.PMID: 12488340 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Pioglitazone reduces islet triglyceride content and restores impaired glucose-stimulated insulin secretion in heterozygous peroxisome proliferator-activated receptor-gamma-deficient mice on a high-fat diet.

    Matsui J, Terauchi Y, Kubota N, Takamoto I, Eto K, Yamashita T, Komeda K, Yamauchi T, Kamon J, Kita S, Noda M, Kadowaki T.

    Diabetes. 2004 Nov;53(11):2844-54.PMID: 15504964 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Peroxisome proliferator-activated receptor-alpha regulates the expression of pancreatic/duodenal homeobox-1 in rat insulinoma (INS-1) cells and ameliorates glucose-induced insulin secretion impaired by palmitate.

    Sun Y, Zhang L, Gu HF, Han W, Ren M, Wang F, Gong B, Wang L, Guo H, Xin W, Zhao J, Gao L.

    Endocrinology. 2008 Feb;149(2):662-71. Epub 2007 Nov 8.PMID: 17991720 [PubMed - indexed for MEDLINE]Related articlesFree article

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