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    Results: 1 to 20 of 212

    1.

    Liver X receptor activation stimulates insulin secretion via modulation of glucose and lipid metabolism in pancreatic beta-cells.

    Efanov AM, Sewing S, Bokvist K, Gromada J.

    Diabetes. 2004 Dec;53 Suppl 3:S75-8.PMID: 15561926 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Sterol regulatory element-binding protein 1 mediates liver X receptor-beta-induced increases in insulin secretion and insulin messenger ribonucleic acid levels.

    Zitzer H, Wente W, Brenner MB, Sewing S, Buschard K, Gromada J, Efanov AM.

    Endocrinology. 2006 Aug;147(8):3898-905. Epub 2006 Apr 27.PMID: 16644917 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Activation of liver X receptors and retinoid X receptors induces growth arrest and apoptosis in insulin-secreting cells.

    Wente W, Brenner MB, Zitzer H, Gromada J, Efanov AM.

    Endocrinology. 2007 Apr;148(4):1843-9. Epub 2006 Dec 28.PMID: 17194744 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Elevated insulin secretion from liver X receptor-activated pancreatic beta-cells involves increased de novo lipid synthesis and triacylglyceride turnover.

    Green CD, Jump DB, Olson LK.

    Endocrinology. 2009 Jun;150(6):2637-45. Epub 2009 Feb 19.PMID: 19228891 [PubMed - indexed for MEDLINE]Related articles

    5.

    Selective modification of pyruvate dehydrogenase kinase isoform expression in rat pancreatic islets elicited by starvation and activation of peroxisome proliferator-activated receptor-alpha: implications for glucose-stimulated insulin secretion.

    Sugden MC, Bulmer K, Augustine D, Holness MJ.

    Diabetes. 2001 Dec;50(12):2729-36.PMID: 11723055 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR).

    Diraison F, Parton L, Ferré P, Foufelle F, Briscoe CP, Leclerc I, Rutter GA.

    Biochem J. 2004 Mar 15;378(Pt 3):769-78.PMID: 14690455 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-alpha gene in the pancreatic beta -cell.

    Roduit R, Morin J, Massé F, Segall L, Roche E, Newgard CB, Assimacopoulos-Jeannet F, Prentki M.

    J Biol Chem. 2000 Nov 17;275(46):35799-806.PMID: 10967113 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Evidence for an anaplerotic/malonyl-CoA pathway in pancreatic beta-cell nutrient signaling.

    Brun T, Roche E, Assimacopoulos-Jeannet F, Corkey BE, Kim KH, Prentki M.

    Diabetes. 1996 Feb;45(2):190-8.PMID: 8549864 [PubMed - indexed for MEDLINE]Related articles

    9.

    Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion.

    Wang MY, Koyama K, Shimabukuro M, Mangelsdorf D, Newgard CB, Unger RH.

    Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11921-6.PMID: 9751766 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Regulation of gene expression by glucose in pancreatic beta -cells (MIN6) via insulin secretion and activation of phosphatidylinositol 3'-kinase.

    da Silva Xavier G, Varadi A, Ainscow EK, Rutter GA.

    J Biol Chem. 2000 Nov 17;275(46):36269-77.PMID: 10967119 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Acute (24 h) activation of peroxisome proliferator-activated receptor-alpha (PPARalpha) reverses high-fat feeding-induced insulin hypersecretion in vivo and in perifused pancreatic islets.

    Holness MJ, Smith ND, Greenwood GK, Sugden MC.

    J Endocrinol. 2003 May;177(2):197-205.PMID: 12740007 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Chronic activation of liver X receptor induces beta-cell apoptosis through hyperactivation of lipogenesis: liver X receptor-mediated lipotoxicity in pancreatic beta-cells.

    Choe SS, Choi AH, Lee JW, Kim KH, Chung JJ, Park J, Lee KM, Park KG, Lee IK, Kim JB.

    Diabetes. 2007 Jun;56(6):1534-43. Epub 2007 Mar 16.PMID: 17369526 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Glucose regulates LXRalpha subcellular localization and function in rat pancreatic beta-cells.

    Helleboid-Chapman A, Helleboid S, Jakel H, Timmerman C, Sergheraert C, Pattou F, Fruchart-Najib J, Fruchart JC.

    Cell Res. 2006 Jul;16(7):661-70.PMID: 16773041 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Hepatocyte nuclear factor-4alpha is essential for glucose-stimulated insulin secretion by pancreatic beta-cells.

    Miura A, Yamagata K, Kakei M, Hatakeyama H, Takahashi N, Fukui K, Nammo T, Yoneda K, Inoue Y, Sladek FM, Magnuson MA, Kasai H, Miyagawa J, Gonzalez FJ, Shimomura I.

    J Biol Chem. 2006 Feb 24;281(8):5246-57. Epub 2005 Dec 23.PMID: 16377800 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Glucose-regulated glucagon secretion requires insulin receptor expression in pancreatic alpha-cells.

    Diao J, Asghar Z, Chan CB, Wheeler MB.

    J Biol Chem. 2005 Sep 30;280(39):33487-96. Epub 2005 Jul 14.PMID: 16027126 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Role of nuclear receptors in the modulation of insulin secretion in lipid-induced insulin resistance.

    Sugden MC, Holness MJ.

    Biochem Soc Trans. 2008 Oct;36(Pt 5):891-900. Review.PMID: 18793157 [PubMed - indexed for MEDLINE]Related articles

    17.

    Effects of free fatty acids on beta-cell functions: a possible involvement of peroxisome proliferator-activated receptors alpha or pancreatic/duodenal homeobox.

    Yoshikawa H, Tajiri Y, Sako Y, Hashimoto T, Umeda F, Nawata H.

    Metabolism. 2001 May;50(5):613-8.PMID: 11319727 [PubMed - indexed for MEDLINE]Related articles

    18.

    Dehydroepiandrosterone sulfate and beta-cell function: enhanced glucose-induced insulin secretion and altered gene expression in rodent pancreatic beta-cells.

    Dillon JS, Yaney GC, Zhou Y, Voilley N, Bowen S, Chipkin S, Bliss CR, Schultz V, Schuit FC, Prentki M, Waxman DJ, Corkey BE.

    Diabetes. 2000 Dec;49(12):2012-20.PMID: 11118002 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Impact of PPARgamma overexpression and activation on pancreatic islet gene expression profile analyzed with oligonucleotide microarrays.

    Parton LE, Diraison F, Neill SE, Ghosh SK, Rubino MA, Bisi JE, Briscoe CP, Rutter GA.

    Am J Physiol Endocrinol Metab. 2004 Sep;287(3):E390-404. Epub 2004 May 4.PMID: 15126236 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Insulin induction of glucokinase and fatty acid synthase in hepatocytes: analysis of the roles of sterol-regulatory-element-binding protein-1c and liver X receptor.

    Hansmannel F, Mordier S, Iynedjian PB.

    Biochem J. 2006 Oct 15;399(2):275-83. Erratum in: Biochem J. 2008 May 1;411(3):697. PMID: 16834571 [PubMed - indexed for MEDLINE]Related articlesFree article

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