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    Results: 1 to 20 of 135

    1.

    Suppression of Beta-cell secretion by somatostatin does not fully reverse the disproportionate proinsulinemia of type 2 diabetes.

    Røder ME, Kahn SE.

    Diabetes. 2004 Dec;53 Suppl 3:S22-5.PMID: 15561914 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Intact proinsulin and beta-cell function in lean and obese subjects with and without type 2 diabetes.

    Røder ME, Dinesen B, Hartling SG, Houssa P, Vestergaard H, Sodoyez-Goffaux F, Binder C.

    Diabetes Care. 1999 Apr;22(4):609-14.PMID: 10189540 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Reduced pancreatic B cell compensation to the insulin resistance of aging: impact on proinsulin and insulin levels.

    Røder ME, Schwartz RS, Prigeon RL, Kahn SE.

    J Clin Endocrinol Metab. 2000 Jun;85(6):2275-80.PMID: 10852463 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Disproportionately elevated proinsulin levels reflect the degree of impaired B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus.

    Røder ME, Porte D Jr, Schwartz RS, Kahn SE.

    J Clin Endocrinol Metab. 1998 Feb;83(2):604-8.PMID: 9467581 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Release of incompletely processed proinsulin is the cause of the disproportionate proinsulinemia of NIDDM.

    Kahn SE, Halban PA.

    Diabetes. 1997 Nov;46(11):1725-32.PMID: 9356018 [PubMed - indexed for MEDLINE]Related articles

    6.

    Parallel changes of proinsulin and islet amyloid polypeptide in glucose intolerance.

    MacNamara CM, Barrow BA, Manley SE, Levy JC, Clark A, Turner RC.

    Diabetes Res Clin Pract. 2000 Oct;50(2):117-26.PMID: 10960722 [PubMed - indexed for MEDLINE]Related articles

    7.

    [Evaluation of islet beta cell function in subjects with normal glucose tolerance, impaired glucose regulation, and type 2 diabetes mellitus]

    Liu J, Li YB, Shao H, Li YX, Yuan YH, Xiao YB, Weng JP.

    Zhonghua Yi Xue Za Zhi. 2007 May 15;87(18):1252-5. Chinese. PMID: 17686259 [PubMed - indexed for MEDLINE]Related articles

    8.

    Overnight inhibition of insulin secretion restores pulsatility and proinsulin/insulin ratio in type 2 diabetes.

    Laedtke T, Kjems L, Pørksen N, Schmitz O, Veldhuis J, Kao PC, Butler PC.

    Am J Physiol Endocrinol Metab. 2000 Sep;279(3):E520-8.PMID: 10950818 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Beta-cell dysfunction in subjects with impaired glucose tolerance and early type 2 diabetes: comparison of surrogate markers with first-phase insulin secretion from an intravenous glucose tolerance test.

    Festa A, Williams K, Hanley AJ, Haffner SM.

    Diabetes. 2008 Jun;57(6):1638-44. Epub 2008 Mar 10.PMID: 18332099 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Proinsulin immunoreactivity in identical twins discordant for noninsulin-dependent diabetes mellitus.

    Røder ME, Vaag A, Hartling SG, Dinesen B, Lanng S, Beck-Nielsen H, Binder C.

    J Clin Endocrinol Metab. 1995 Aug;80(8):2359-63.PMID: 7629230 [PubMed - indexed for MEDLINE]Related articles

    11.

    Compared to glibenclamide, repaglinide treatment results in a more rapid fall in glucose level and beta-cell secretion after glucose stimulation.

    Abbink EJ, van der Wal PS, Sweep CG, Smits P, Tack CJ.

    Diabetes Metab Res Rev. 2004 Nov-Dec;20(6):466-71.PMID: 15386823 [PubMed - indexed for MEDLINE]Related articles

    12.

    Hyperproinsulinemia in the diabetic Psammomys obesus is a result of increased secretory demand on the beta-cell.

    Gadot M, Ariav Y, Cerasi E, Kaiser N, Gross DJ.

    Endocrinology. 1995 Oct;136(10):4218-23.PMID: 7664638 [PubMed - indexed for MEDLINE]Related articles

    13.

    Serum insulin, proinsulin and proinsulin/insulin ratio in type 2 diabetic patients: as an index of beta-cell function or insulin resistance.

    Kim NH, Kim DL, Choi KM, Baik SH, Choi DS.

    Korean J Intern Med. 2000 Dec;15(3):195-201.PMID: 11242807 [PubMed - indexed for MEDLINE]Related articles

    14.

    Relationships among age, proinsulin conversion, and beta-cell function in nondiabetic humans.

    Fritsche A, Madaus A, Stefan N, Tschritter O, Maerker E, Teigeler A, Häring H, Stumvoll M.

    Diabetes. 2002 Feb;51 Suppl 1:S234-9.PMID: 11815485 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    The impact of insulin resistance on proinsulin secretion in pregnancy: hyperproinsulinemia is not a feature of gestational diabetes.

    Retnakaran R, Hanley AJ, Sermer M, Zinman B.

    Diabetes Care. 2005 Nov;28(11):2710-5.PMID: 16249544 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Chronic sulfonylurea treatment and hyperglycemia aggravate disproportionately elevated plasma proinsulin levels in patients with type 2 diabetes.

    Inoguchi T, Umeda F, Kakimoto M, Sako Y, Ishii H, Noda K, Kunisaki M, Imamura M, Yu HY, Etoh T, Yoshikawa H, Aoki T, Hashimoto T, Nawata H.

    Endocr J. 2000 Dec;47(6):763-70.PMID: 11228051 [PubMed - indexed for MEDLINE]Related articles

    17.

    Disproportionate elevation of immunoreactive proinsulin in type 2 (non-insulin-dependent) diabetes mellitus and in experimental insulin resistance.

    Ward WK, LaCava EC, Paquette TL, Beard JC, Wallum BJ, Porte D Jr.

    Diabetologia. 1987 Sep;30(9):698-702.PMID: 3322910 [PubMed - indexed for MEDLINE]Related articles

    18.

    [Characteristics of dysfunction of islet beta-cell in newly diagnosed type 2 diabetic patients]

    Li YB, Zhu DL, Tian HM, Shi LX, Luo ZJ, Yan L, Zeng LY, Zhou ZG, Yang LY, Liu J, Li M, Weng JP.

    Zhonghua Yi Xue Za Zhi. 2006 Sep 26;86(36):2537-41. Chinese. PMID: 17198561 [PubMed - indexed for MEDLINE]Related articles

    19.

    [Blood levels of true insulin and immunoreactive insulin in evaluating beta-cell function with arginine stimulation test]

    Ma XJ, Jia WP, Zhou J, Lu HJ, Lu JQ, Wu SH.

    Zhejiang Da Xue Xue Bao Yi Xue Ban. 2006 May;35(3):255-9. Chinese. PMID: 16764026 [PubMed - indexed for MEDLINE]Related articles

    20.

    Hyperproinsulinemia is associated with increased beta cell demand after hemipancreatectomy in humans.

    Seaquist ER, Kahn SE, Clark PM, Hales CN, Porte D Jr, Robertson RP.

    J Clin Invest. 1996 Jan 15;97(2):455-60.PMID: 8567967 [PubMed - indexed for MEDLINE]Related articlesFree article

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