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    Results: 1 to 20 of 107

    1.

    ATP-sensitive K+ channel knockout compromises the metabolic benefit of exercise training, resulting in cardiac deficits.

    Kane GC, Behfar A, Yamada S, Perez-Terzic C, O'Cochlain F, Reyes S, Dzeja PP, Miki T, Seino S, Terzic A.

    Diabetes. 2004 Dec;53 Suppl 3:S169-75.PMID: 15561907 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Protection conferred by myocardial ATP-sensitive K+ channels in pressure overload-induced congestive heart failure revealed in KCNJ11 Kir6.2-null mutant.

    Yamada S, Kane GC, Behfar A, Liu XK, Dyer RB, Faustino RS, Miki T, Seino S, Terzic A.

    J Physiol. 2006 Dec 15;577(Pt 3):1053-65. Epub 2006 Oct 12.PMID: 17038430 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Behavioral phenotyping of mice lacking the K ATP channel subunit Kir6.2.

    Deacon RM, Brook RC, Meyer D, Haeckel O, Ashcroft FM, Miki T, Seino S, Liss B.

    Physiol Behav. 2006 Apr 15;87(4):723-33. Epub 2006 Mar 10.PMID: 16530794 [PubMed - indexed for MEDLINE]Related articles

    4.

    Gene knockout of the KCNJ8-encoded Kir6.1 K(ATP) channel imparts fatal susceptibility to endotoxemia.

    Kane GC, Lam CF, O'Cochlain F, Hodgson DM, Reyes S, Liu XK, Miki T, Seino S, Katusic ZS, Terzic A.

    FASEB J. 2006 Nov;20(13):2271-80.PMID: 17077304 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Disruption of sarcolemmal ATP-sensitive potassium channel activity impairs the cardiac response to systolic overload.

    Hu X, Xu X, Huang Y, Fassett J, Flagg TP, Zhang Y, Nichols CG, Bache RJ, Chen Y.

    Circ Res. 2008 Oct 24;103(9):1009-17. Epub 2008 Sep 18.PMID: 18802029 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    KATP channel knockout worsens myocardial calcium stress load in vivo and impairs recovery in stunned heart.

    Gumina RJ, O'Cochlain DF, Kurtz CE, Bast P, Pucar D, Mishra P, Miki T, Seino S, Macura S, Terzic A.

    Am J Physiol Heart Circ Physiol. 2007 Apr;292(4):H1706-13. Epub 2006 Dec 22.PMID: 17189350 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Kir6.2-deficient mice are susceptible to stimulated ANP secretion: K(ATP) channel acts as a negative feedback mechanism?

    Saegusa N, Sato T, Saito T, Tamagawa M, Komuro I, Nakaya H.

    Cardiovasc Res. 2005 Jul 1;67(1):60-8. Epub 2005 Apr 20.PMID: 15949470 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Kir6.2 is required for adaptation to stress.

    Zingman LV, Hodgson DM, Bast PH, Kane GC, Perez-Terzic C, Gumina RJ, Pucar D, Bienengraeber M, Dzeja PP, Miki T, Seino S, Alekseev AE, Terzic A.

    Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13278-83. Epub 2002 Sep 23.PMID: 12271142 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Enhanced neuronal damage after ischemic insults in mice lacking Kir6.2-containing ATP-sensitive K+ channels.

    Sun HS, Feng ZP, Miki T, Seino S, French RJ.

    J Neurophysiol. 2006 Apr;95(4):2590-601. Epub 2005 Dec 14.PMID: 16354731 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Gene targeting approach to clarification of ion channel function: studies of Kir6.x null mice.

    Seino S, Miki T.

    J Physiol. 2004 Jan 15;554(Pt 2):295-300. Epub 2003 Jun 25. Review.PMID: 12826653 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Roles of ATP-sensitive K+ channels as metabolic sensors: studies of Kir6.x null mice.

    Minami K, Miki T, Kadowaki T, Seino S.

    Diabetes. 2004 Dec;53 Suppl 3:S176-80. Review.PMID: 15561908 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Knockout of Kir6.2 negates ischemic preconditioning-induced protection of myocardial energetics.

    Gumina RJ, Pucar D, Bast P, Hodgson DM, Kurtz CE, Dzeja PP, Miki T, Seino S, Terzic A.

    Am J Physiol Heart Circ Physiol. 2003 Jun;284(6):H2106-13. Epub 2003 Feb 21.PMID: 12598229 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Cerebral glucose transporters expression and spatial learning in the K-ATP Kir6.2(-/-) knockout mice.

    Choeiri C, Staines WA, Miki T, Seino S, Renaud JM, Teutenberg K, Messier C.

    Behav Brain Res. 2006 Sep 25;172(2):233-9. Epub 2006 Jun 23.PMID: 16797737 [PubMed - indexed for MEDLINE]Related articles

    14.

    Role of ATP-sensitive K+ channels in electrophysiological alterations during myocardial ischemia: a study using Kir6.2-null mice.

    Saito T, Sato T, Miki T, Seino S, Nakaya H.

    Am J Physiol Heart Circ Physiol. 2005 Jan;288(1):H352-7.PMID: 15598870 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Genetic disruption of Kir6.2, the pore-forming subunit of ATP-sensitive K+ channel, predisposes to catecholamine-induced ventricular dysrhythmia.

    Liu XK, Yamada S, Kane GC, Alekseev AE, Hodgson DM, O'Cochlain F, Jahangir A, Miki T, Seino S, Terzic A.

    Diabetes. 2004 Dec;53 Suppl 3:S165-8.PMID: 15561906 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    KCNJ11 gene knockout of the Kir6.2 KATP channel causes maladaptive remodeling and heart failure in hypertension.

    Kane GC, Behfar A, Dyer RB, O'Cochlain DF, Liu XK, Hodgson DM, Reyes S, Miki T, Seino S, Terzic A.

    Hum Mol Genet. 2006 Aug 1;15(15):2285-97. Epub 2006 Jun 16.PMID: 16782803 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    ATP-sensitive K+ channel signaling in glucokinase-deficient diabetes.

    Remedi MS, Koster JC, Patton BL, Nichols CG.

    Diabetes. 2005 Oct;54(10):2925-31.PMID: 16186394 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Kir6.2-containing ATP-sensitive potassium channels protect cortical neurons from ischemic/anoxic injury in vitro and in vivo.

    Sun HS, Feng ZP, Barber PA, Buchan AM, French RJ.

    Neuroscience. 2007 Feb 23;144(4):1509-15. Epub 2006 Dec 18.PMID: 17175112 [PubMed - indexed for MEDLINE]Related articles

    19.

    Consequences of cardiac myocyte-specific ablation of KATP channels in transgenic mice expressing dominant negative Kir6 subunits.

    Tong X, Porter LM, Liu G, Dhar-Chowdhury P, Srivastava S, Pountney DJ, Yoshida H, Artman M, Fishman GI, Yu C, Iyer R, Morley GE, Gutstein DE, Coetzee WA.

    Am J Physiol Heart Circ Physiol. 2006 Aug;291(2):H543-51. Epub 2006 Feb 24.PMID: 16501027 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Mouse model of Prinzmetal angina by disruption of the inward rectifier Kir6.1.

    Miki T, Suzuki M, Shibasaki T, Uemura H, Sato T, Yamaguchi K, Koseki H, Iwanaga T, Nakaya H, Seino S.

    Nat Med. 2002 May;8(5):466-72.PMID: 11984590 [PubMed - indexed for MEDLINE]Related articles

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