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    Results: 1 to 20 of 108

    1.

    Genetic disruption of Kir6.2, the pore-forming subunit of ATP-sensitive K+ channel, predisposes to catecholamine-induced ventricular dysrhythmia.

    Liu XK, Yamada S, Kane GC, Alekseev AE, Hodgson DM, O'Cochlain F, Jahangir A, Miki T, Seino S, Terzic A.

    Diabetes. 2004 Dec;53 Suppl 3:S165-8.PMID: 15561906 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Functional roles of cardiac and vascular ATP-sensitive potassium channels clarified by Kir6.2-knockout mice.

    Suzuki M, Li RA, Miki T, Uemura H, Sakamoto N, Ohmoto-Sekine Y, Tamagawa M, Ogura T, Seino S, Marbán E, Nakaya H.

    Circ Res. 2001 Mar 30;88(6):570-7.PMID: 11282890 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Cardiac KATP channels in health and disease.

    Kane GC, Liu XK, Yamada S, Olson TM, Terzic A.

    J Mol Cell Cardiol. 2005 Jun;38(6):937-43. Epub 2005 Apr 25. Review.PMID: 15910878 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Protection conferred by myocardial ATP-sensitive K+ channels in pressure overload-induced congestive heart failure revealed in KCNJ11 Kir6.2-null mutant.

    Yamada S, Kane GC, Behfar A, Liu XK, Dyer RB, Faustino RS, Miki T, Seino S, Terzic A.

    J Physiol. 2006 Dec 15;577(Pt 3):1053-65. Epub 2006 Oct 12.PMID: 17038430 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    KATP channel knockout worsens myocardial calcium stress load in vivo and impairs recovery in stunned heart.

    Gumina RJ, O'Cochlain DF, Kurtz CE, Bast P, Pucar D, Mishra P, Miki T, Seino S, Macura S, Terzic A.

    Am J Physiol Heart Circ Physiol. 2007 Apr;292(4):H1706-13. Epub 2006 Dec 22.PMID: 17189350 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Disruption of sarcolemmal ATP-sensitive potassium channel activity impairs the cardiac response to systolic overload.

    Hu X, Xu X, Huang Y, Fassett J, Flagg TP, Zhang Y, Nichols CG, Bache RJ, Chen Y.

    Circ Res. 2008 Oct 24;103(9):1009-17. Epub 2008 Sep 18.PMID: 18802029 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Role of ATP-sensitive K+ channels in electrophysiological alterations during myocardial ischemia: a study using Kir6.2-null mice.

    Saito T, Sato T, Miki T, Seino S, Nakaya H.

    Am J Physiol Heart Circ Physiol. 2005 Jan;288(1):H352-7.PMID: 15598870 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Gene knockout of the KCNJ8-encoded Kir6.1 K(ATP) channel imparts fatal susceptibility to endotoxemia.

    Kane GC, Lam CF, O'Cochlain F, Hodgson DM, Reyes S, Liu XK, Miki T, Seino S, Katusic ZS, Terzic A.

    FASEB J. 2006 Nov;20(13):2271-80.PMID: 17077304 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Consequences of cardiac myocyte-specific ablation of KATP channels in transgenic mice expressing dominant negative Kir6 subunits.

    Tong X, Porter LM, Liu G, Dhar-Chowdhury P, Srivastava S, Pountney DJ, Yoshida H, Artman M, Fishman GI, Yu C, Iyer R, Morley GE, Gutstein DE, Coetzee WA.

    Am J Physiol Heart Circ Physiol. 2006 Aug;291(2):H543-51. Epub 2006 Feb 24.PMID: 16501027 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Kir6.2 is required for adaptation to stress.

    Zingman LV, Hodgson DM, Bast PH, Kane GC, Perez-Terzic C, Gumina RJ, Pucar D, Bienengraeber M, Dzeja PP, Miki T, Seino S, Alekseev AE, Terzic A.

    Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13278-83. Epub 2002 Sep 23.PMID: 12271142 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Gene targeting approach to clarification of ion channel function: studies of Kir6.x null mice.

    Seino S, Miki T.

    J Physiol. 2004 Jan 15;554(Pt 2):295-300. Epub 2003 Jun 25. Review.PMID: 12826653 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    KCNJ11 gene knockout of the Kir6.2 KATP channel causes maladaptive remodeling and heart failure in hypertension.

    Kane GC, Behfar A, Dyer RB, O'Cochlain DF, Liu XK, Hodgson DM, Reyes S, Miki T, Seino S, Terzic A.

    Hum Mol Genet. 2006 Aug 1;15(15):2285-97. Epub 2006 Jun 16.PMID: 16782803 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Knockout of Kir6.2 negates ischemic preconditioning-induced protection of myocardial energetics.

    Gumina RJ, Pucar D, Bast P, Hodgson DM, Kurtz CE, Dzeja PP, Miki T, Seino S, Terzic A.

    Am J Physiol Heart Circ Physiol. 2003 Jun;284(6):H2106-13. Epub 2003 Feb 21.PMID: 12598229 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Identification and characterization of a novel member of the ATP-sensitive K+ channel subunit family, Kir6.3, in zebrafish.

    Zhang C, Miki T, Shibasaki T, Yokokura M, Saraya A, Seino S.

    Physiol Genomics. 2006 Feb 14;24(3):290-7. Epub 2005 Nov 29.PMID: 16317080 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Behavioral phenotyping of mice lacking the K ATP channel subunit Kir6.2.

    Deacon RM, Brook RC, Meyer D, Haeckel O, Ashcroft FM, Miki T, Seino S, Liss B.

    Physiol Behav. 2006 Apr 15;87(4):723-33. Epub 2006 Mar 10.PMID: 16530794 [PubMed - indexed for MEDLINE]Related articles

    16.

    Roles of ATP-sensitive K+ channels as metabolic sensors: studies of Kir6.x null mice.

    Minami K, Miki T, Kadowaki T, Seino S.

    Diabetes. 2004 Dec;53 Suppl 3:S176-80. Review.PMID: 15561908 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Human ether-a-go-go-related (HERG) gene and ATP-sensitive potassium channels as targets for adverse drug effects.

    Zünkler BJ.

    Pharmacol Ther. 2006 Oct;112(1):12-37. Epub 2006 May 2. Review.PMID: 16647758 [PubMed - indexed for MEDLINE]Related articles

    18.

    Elimination of allosteric modulation of myocardial KATP channels by ATP and protons in two Kir6.2 polymorphisms found in sudden cardiac death.

    Cui N, Li L, Wang X, Shi Y, Shi W, Jiang C.

    Physiol Genomics. 2006 Mar 13;25(1):105-15. Epub 2006 Jan 10.PMID: 16403845 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    A mutation in the ATP-binding site of the Kir6.2 subunit of the KATP channel alters coupling with the SUR2A subunit.

    Tammaro P, Ashcroft FM.

    J Physiol. 2007 Nov 1;584(Pt 3):743-53. Epub 2007 Sep 13.PMID: 17855752 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Zinc is both an intracellular and extracellular regulator of KATP channel function.

    Prost AL, Bloc A, Hussy N, Derand R, Vivaudou M.

    J Physiol. 2004 Aug 15;559(Pt 1):157-67. Epub 2004 Jun 24.PMID: 15218066 [PubMed - indexed for MEDLINE]Related articlesFree article

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