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Desensitization of insulin secretion by depolarizing insulin secretagogues.

Rustenbeck I, Wienbergen A, Bleck C, Jörns A.

Diabetes. 2004 Dec;53 Suppl 3:S140-50. Review.PMID: 15561902 [PubMed - indexed for MEDLINE]Related articlesFree article

Desensitization of insulin secretory response to imidazolines, tolbutamide, and quinine. II. Electrophysiological and fluorimetric studies.

Rustenbeck I, Dickel C, Grimmsmanns T.

Biochem Pharmacol. 2001 Dec 15;62(12):1695-703.PMID: 11755123 [PubMed - indexed for MEDLINE]Related articles

ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line.

Chapman JC, McClenaghan NH, Cosgrove KE, Hashmi MN, Shepherd RM, Giesberts AN, White SJ, Ammälä C, Flatt PR, Dunne MJ.

Diabetes. 1999 Dec;48(12):2349-57.PMID: 10580423 [PubMed - indexed for MEDLINE]Related articlesFree article

Essential role of the imidazoline moiety in the insulinotropic effect but not the KATP channel-blocking effect of imidazolines; a comparison of the effects of efaroxan and its imidazole analogue, KU14R.

Bleck C, Wienbergen A, Rustenbeck I.

Diabetologia. 2005 Dec;48(12):2567-75. Epub 2005 Nov 11.PMID: 16283242 [PubMed - indexed for MEDLINE]Related articles

Heterogeneous characteristics of imidazoline-induced insulin secretion.

Rustenbeck I, Leupolt L, Kowalewski R, Hasselblatt A.

Naunyn Schmiedebergs Arch Pharmacol. 1999 Mar;359(3):235-42.PMID: 10208311 [PubMed - indexed for MEDLINE]Related articles

Desensitization of insulin secretory response to imidazolines, tolbutamide, and quinine. I. Secretory and morphological studies.

Rustenbeck I, Winkler M, Jörns A.

Biochem Pharmacol. 2001 Dec 15;62(12):1685-94.PMID: 11755122 [PubMed - indexed for MEDLINE]Related articles

Glucose dependence of imidazoline-induced insulin secretion: different characteristics of two ATP-Sensitive K+ channel-blocking compounds.

Bleck C, Wienbergen A, Rustenbeck I.

Diabetes. 2004 Dec;53 Suppl 3:S135-9.PMID: 15561901 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of a KATP channel-independent pathway involved in potentiation of insulin secretion by efaroxan.

Chan SL, Mourtada M, Morgan NG.

Diabetes. 2001 Feb;50(2):340-7.PMID: 11272145 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta-cell toxicity of ATP-sensitive K+ channel-blocking insulin secretagogues.

Rustenbeck I, Krautheim A, Jörns A, Steinfelder HJ.

Biochem Pharmacol. 2004 May 1;67(9):1733-41.PMID: 15081872 [PubMed - indexed for MEDLINE]Related articles

Clotrimazole and efaroxan stimulate insulin secretion by different mechanisms in rat pancreatic islets.

Chan SL, Pallett AL, Morgan NG.

Naunyn Schmiedebergs Arch Pharmacol. 1997 Dec;356(6):763-8.PMID: 9453462 [PubMed - indexed for MEDLINE]Related articles

Imidazolines and the pancreatic B-cell. Actions and binding sites.

Rustenbeck I, Köpp M, Ratzka P, Leupolt L, Hasselblatt A.

Ann N Y Acad Sci. 1999 Jun 21;881:229-40.PMID: 10415921 [PubMed - indexed for MEDLINE]Related articles

Elevation of cytosolic calcium by imidazolines in mouse islets of Langerhans: implications for stimulus-response coupling of insulin release.

Shepherd RM, Hashmi MN, Kane C, Squires PE, Dunne MJ.

Br J Pharmacol. 1996 Nov;119(5):911-6.PMID: 8922740 [PubMed - indexed for MEDLINE]Related articlesFree article

The imidazoline RX871024 stimulates insulin secretion in pancreatic beta-cells from mice deficient in K(ATP) channel function.

Efanov AM, Høy M, Bränström R, Zaitsev SV, Magnuson MA, Efendic S, Gromada J, Berggren PO.

Biochem Biophys Res Commun. 2001 Jun 22;284(4):918-22.PMID: 11409880 [PubMed - indexed for MEDLINE]Related articles

Drug-induced desensitization of insulinotropic actions of sulfonylureas.

Ball AJ, McCluskey JT, Flatt PR, McClenaghan NH.

Biochem Biophys Res Commun. 2000 Apr 29;271(1):234-9.PMID: 10777708 [PubMed - indexed for MEDLINE]Related articles

Effects of imidazoline binding site ligands on the growth and viability of clonal pancreatic beta-cells.

Mourtada M, Elliott J, Smith SA, Morgan NG.

Naunyn Schmiedebergs Arch Pharmacol. 2000 Feb;361(2):146-54.PMID: 10685869 [PubMed - indexed for MEDLINE]Related articles

Desensitization of insulin secretion.

Rustenbeck I.

Biochem Pharmacol. 2002 Jun 1;63(11):1921-35. Review.PMID: 12093468 [PubMed - indexed for MEDLINE]Related articles

Stimulation of insulin secretion by efaroxan may involve interaction with potassium channels.

Chan SL, Morgan NG.

Eur J Pharmacol. 1990 Jan 25;176(1):97-101.PMID: 2178947 [PubMed - indexed for MEDLINE]Related articles

Effects of the imidazoline binding site ligands, idazoxan and efaroxan, on the viability of insulin-secreting BRIN-BD11 cells.

Gao H, Mourtada M, Morgan NG.

JOP. 2003 May;4(3):117-24.PMID: 12743417 [PubMed - indexed for MEDLINE]Related articlesFree article

Specific desensitization of sulfonylurea- but not imidazoline-induced insulin release after prolonged tolbutamide exposure.

McClenaghan NH, Ball AJ, Flatt PR.

Biochem Pharmacol. 2001 Mar 1;61(5):527-36.PMID: 11239495 [PubMed - indexed for MEDLINE]Related articles

Membrane phosphoinositides control insulin secretion through their effects on ATP-sensitive K+ channel activity.

Lin CW, Yan F, Shimamura S, Barg S, Shyng SL.

Diabetes. 2005 Oct;54(10):2852-8.PMID: 16186385 [PubMed - indexed for MEDLINE]Related articlesFree article