PubMed

Glucose dependence of imidazoline-induced insulin secretion: different characteristics of two ATP-Sensitive K+ channel-blocking compounds.

Bleck C, Wienbergen A, Rustenbeck I.

Diabetes. 2004 Dec;53 Suppl 3:S135-9.PMID: 15561901 [PubMed - indexed for MEDLINE]Related articlesFree article

Essential role of the imidazoline moiety in the insulinotropic effect but not the KATP channel-blocking effect of imidazolines; a comparison of the effects of efaroxan and its imidazole analogue, KU14R.

Bleck C, Wienbergen A, Rustenbeck I.

Diabetologia. 2005 Dec;48(12):2567-75. Epub 2005 Nov 11.PMID: 16283242 [PubMed - indexed for MEDLINE]Related articles

ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line.

Chapman JC, McClenaghan NH, Cosgrove KE, Hashmi MN, Shepherd RM, Giesberts AN, White SJ, Ammälä C, Flatt PR, Dunne MJ.

Diabetes. 1999 Dec;48(12):2349-57.PMID: 10580423 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of a KATP channel-independent pathway involved in potentiation of insulin secretion by efaroxan.

Chan SL, Mourtada M, Morgan NG.

Diabetes. 2001 Feb;50(2):340-7.PMID: 11272145 [PubMed - indexed for MEDLINE]Related articlesFree article

Heterogeneous characteristics of imidazoline-induced insulin secretion.

Rustenbeck I, Leupolt L, Kowalewski R, Hasselblatt A.

Naunyn Schmiedebergs Arch Pharmacol. 1999 Mar;359(3):235-42.PMID: 10208311 [PubMed - indexed for MEDLINE]Related articles

Clotrimazole and efaroxan stimulate insulin secretion by different mechanisms in rat pancreatic islets.

Chan SL, Pallett AL, Morgan NG.

Naunyn Schmiedebergs Arch Pharmacol. 1997 Dec;356(6):763-8.PMID: 9453462 [PubMed - indexed for MEDLINE]Related articles

Glucose triggers protein kinase A-dependent insulin secretion in mouse pancreatic islets through activation of the K+ATP channel-dependent pathway.

Thams P, Anwar MR, Capito K.

Eur J Endocrinol. 2005 Apr;152(4):671-7.PMID: 15817925 [PubMed - indexed for MEDLINE]Related articlesFree article

Imidazoline NNC77-0074 stimulates insulin secretion and inhibits glucagon release by control of Ca(2+)-dependent exocytosis in pancreatic alpha- and beta-cells.

Høy M, Olsen HL, Andersen HS, Bokvist K, Buschard K, Hansen J, Jacobsen P, Petersen JS, Rorsman P, Gromada J.

Eur J Pharmacol. 2003 Apr 11;466(1-2):213-21.PMID: 12679159 [PubMed - indexed for MEDLINE]Related articles

ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR1-/- mouse alpha-cells.

Gromada J, Ma X, Høy M, Bokvist K, Salehi A, Berggren PO, Rorsman P.

Diabetes. 2004 Dec;53 Suppl 3:S181-9.PMID: 15561909 [PubMed - indexed for MEDLINE]Related articlesFree article

Imidazolines and the pancreatic B-cell. Actions and binding sites.

Rustenbeck I, Köpp M, Ratzka P, Leupolt L, Hasselblatt A.

Ann N Y Acad Sci. 1999 Jun 21;881:229-40.PMID: 10415921 [PubMed - indexed for MEDLINE]Related articles

Differential mechanisms of glucose and palmitate in augmentation of insulin secretion in mouse pancreatic islets.

Thams P, Capito K.

Diabetologia. 2001 Jun;44(6):738-46.PMID: 11440367 [PubMed - indexed for MEDLINE]Related articles

Elevation of cytosolic calcium by imidazolines in mouse islets of Langerhans: implications for stimulus-response coupling of insulin release.

Shepherd RM, Hashmi MN, Kane C, Squires PE, Dunne MJ.

Br J Pharmacol. 1996 Nov;119(5):911-6.PMID: 8922740 [PubMed - indexed for MEDLINE]Related articlesFree article

Stevioside acts directly on pancreatic beta cells to secrete insulin: actions independent of cyclic adenosine monophosphate and adenosine triphosphate-sensitive K+-channel activity.

Jeppesen PB, Gregersen S, Poulsen CR, Hermansen K.

Metabolism. 2000 Feb;49(2):208-14.PMID: 10690946 [PubMed - indexed for MEDLINE]Related articles

Imidazoline compounds stimulate insulin release by inhibition of K(ATP) channels and interaction with the exocytotic machinery.

Zaitsev SV, Efanov AM, Efanova IB, Larsson O, Ostenson CG, Gold G, Berggren PO, Efendić S.

Diabetes. 1996 Nov;45(11):1610-8.PMID: 8866568 [PubMed - indexed for MEDLINE]Related articles

Glucose controls cytosolic Ca2+ and insulin secretion in mouse islets lacking adenosine triphosphate-sensitive K+ channels owing to a knockout of the pore-forming subunit Kir6.2.

Ravier MA, Nenquin M, Miki T, Seino S, Henquin JC.

Endocrinology. 2009 Jan;150(1):33-45. Epub 2008 Sep 11.PMID: 18787024 [PubMed - indexed for MEDLINE]Related articles

Glucose-regulated pulsatile insulin release from mouse islets via the K(ATP) channel-independent pathway.

Westerlund J, Ortsäter H, Palm F, Sundsten T, Bergsten P.

Eur J Endocrinol. 2001 Jun;144(6):667-75.PMID: 11375802 [PubMed - indexed for MEDLINE]Related articlesFree article

Antagonism of the stimulatory effects of efaroxan and glibenclamide in rat pancreatic islets by the imidazoline, RX801080.

Brown CA, Chan SL, Stillings MR, Smith SA, Morgan NG.

Br J Pharmacol. 1993 Nov;110(3):1017-22.PMID: 7905338 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose regulation of insulin secretion independent of the opening or closure of adenosine triphosphate-sensitive K+ channels in beta cells.

Sato Y, Anello M, Henquin JC.

Endocrinology. 1999 May;140(5):2252-7.PMID: 10218978 [PubMed - indexed for MEDLINE]Related articlesFree article

Effector systems involved in the insulin secretory responses to efaroxan and RX871024 in rat islets of Langerhans.

Mourtada M, Smith SA, Morgan NG.

Eur J Pharmacol. 1998 Jun 5;350(2-3):251-8.PMID: 9696415 [PubMed - indexed for MEDLINE]Related articles

Stimulation of insulin secretion by efaroxan may involve interaction with potassium channels.

Chan SL, Morgan NG.

Eur J Pharmacol. 1990 Jan 25;176(1):97-101.PMID: 2178947 [PubMed - indexed for MEDLINE]Related articles