PubMed

CP-31398, a putative p53-stabilizing molecule tested in mammalian cells and in yeast for its effects on p53 transcriptional activity.

Tanner S, Barberis A.

J Negat Results Biomed. 2004 Nov 17;3:5.PMID: 15548325 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Characterization of the p53-rescue drug CP-31398 in vitro and in living cells.

Rippin TM, Bykov VJ, Freund SM, Selivanova G, Wiman KG, Fersht AR.

Oncogene. 2002 Mar 28;21(14):2119-29.PMID: 11948395 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice.

Tang X, Zhu Y, Han L, Kim AL, Kopelovich L, Bickers DR, Athar M.

J Clin Invest. 2007 Dec;117(12):3753-64.PMID: 18060030 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Small-molecule modulators of p53 family signaling and antitumor effects in p53-deficient human colon tumor xenografts.

Wang W, Kim SH, El-Deiry WS.

Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):11003-8. Epub 2006 Jul 11.PMID: 16835297 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

The p53-stabilizing compound, CP-31398, does not enhance chemosensitivity in human melanoma cells.

Luu Y, Li G.

Anticancer Res. 2003 Jan-Feb;23(1A):99-105.PMID: 12680200 [PubMed - indexed for MEDLINE]Related citations

CP-31398 restores DNA-binding activity to mutant p53 in vitro but does not affect p53 homologs p63 and p73.

Demma MJ, Wong S, Maxwell E, Dasmahapatra B.

J Biol Chem. 2004 Oct 29;279(44):45887-96. Epub 2004 Aug 11.PMID: 15308639 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

Reporter gene regulation in Saccharomyces cerevisiae by the human p53 tumor suppressor protein.

Bitter GA, Schaeffer TN, Ellison AR.

J Mol Microbiol Biotechnol. 2002 Nov;4(6):539-50.PMID: 12432954 [PubMed - indexed for MEDLINE]Related citations

Human tumor-derived p53 proteins exhibit binding site selectivity and temperature sensitivity for transactivation in a yeast-based assay.

Di Como CJ, Prives C.

Oncogene. 1998 May 14;16(19):2527-39.PMID: 9627118 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

CP-31398, a novel p53-stabilizing agent, induces p53-dependent and p53-independent glioma cell death.

Wischhusen J, Naumann U, Ohgaki H, Rastinejad F, Weller M.

Oncogene. 2003 Nov 13;22(51):8233-45.PMID: 14614447 [PubMed - indexed for MEDLINE]Related citations

Mutant p53 melanoma cell lines respond differently to CP-31398-induced apoptosis.

Ho CK, Li G.

Br J Dermatol. 2005 Nov;153(5):900-10.PMID: 16225598 [PubMed - indexed for MEDLINE]Related citations

Small-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway.

Kravchenko JE, Ilyinskaya GV, Komarov PG, Agapova LS, Kochetkov DV, Strom E, Frolova EI, Kovriga I, Gudkov AV, Feinstein E, Chumakov PM.

Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6302-7. Epub 2008 Apr 18.PMID: 18424558 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Restoration of the transcription activation function to mutant p53 in human cancer cells.

Abarzúa P, LoSardo JE, Gubler ML, Spathis R, Lu YA, Felix A, Neri A.

Oncogene. 1996 Dec 5;13(11):2477-82.PMID: 8957091 [PubMed - indexed for MEDLINE]Related citations

Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations.

Suad O, Rozenberg H, Brosh R, Diskin-Posner Y, Kessler N, Shimon LJ, Frolow F, Liran A, Rotter V, Shakked Z.

J Mol Biol. 2009 Jan 9;385(1):249-65. Epub 2008 Oct 30.PMID: 18996393 [PubMed - indexed for MEDLINE]Related citations

Differential response between the p53 ubiquitin-protein ligases Pirh2 and MdM2 following DNA damage in human cancer cells.

Duan W, Gao L, Wu X, Zhang Y, Otterson GA, Villalona-Calero MA.

Exp Cell Res. 2006 Oct 15;312(17):3370-8. Epub 2006 Jul 21.PMID: 16934800 [PubMed - indexed for MEDLINE]Related citations

Genetic selection of intragenic suppressor mutations that reverse the effect of common p53 cancer mutations.

Brachmann RK, Yu K, Eby Y, Pavletich NP, Boeke JD.

EMBO J. 1998 Apr 1;17(7):1847-59.PMID: 9524109 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Modulation of beta-catenin-mediated TCF-signalling in prostate cancer cell lines by wild-type and mutant p53.

Prowald A, Cronauer MV, von Klot C, Eilers T, Rinnab L, Herrmann T, Spindler KD, Montenarh M, Jonas U, Burchardt M.

Prostate. 2007 Dec 1;67(16):1751-60.PMID: 17929268 [PubMed - indexed for MEDLINE]Related citations

Suppression of familial adenomatous polyposis by CP-31398, a TP53 modulator, in APCmin/+ mice.

Rao CV, Swamy MV, Patlolla JM, Kopelovich L.

Cancer Res. 2008 Sep 15;68(18):7670-5.PMID: 18794156 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Noncanonical DNA motifs as transactivation targets by wild type and mutant p53.

Jordan JJ, Menendez D, Inga A, Noureddine M, Bell DA, Resnick MA.

PLoS Genet. 2008 Jun 27;4(6):e1000104. Erratum in: PLoS Genet. 2008 Nov;4(11).doi.org/10.1371/annotation/f7fc9c28-14ae-480d-a69e-ee9cc4fba9a7. PLoS Genet. 2008 Jul;4(7). doi: 10.1371/annotation/13bc83be-2345-401d-b953-f1886e9fbdff. Nourredine, Maher [corrected to Noureddine, Maher]; Bell, Douglas [corrected to Bell, Douglas A]. PMID: 18714371 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

Bykov VJ, Issaeva N, Shilov A, Hultcrantz M, Pugacheva E, Chumakov P, Bergman J, Wiman KG, Selivanova G.

Nat Med. 2002 Mar;8(3):282-8.PMID: 11875500 [PubMed - indexed for MEDLINE]Related citations

Amifostine (WR2721) restores transcriptional activity of specific p53 mutant proteins in a yeast functional assay.

Maurici D, Monti P, Campomenosi P, North S, Frebourg T, Fronza G, Hainaut P.

Oncogene. 2001 Jun 14;20(27):3533-40.PMID: 11429700 [PubMed - indexed for MEDLINE]Free ArticleRelated citations