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    Results: 1 to 20 of 195

    1.

    Common variants of the hepatocyte nuclear factor-4alpha P2 promoter are associated with type 2 diabetes in the U.K. population.

    Weedon MN, Owen KR, Shields B, Hitman G, Walker M, McCarthy MI, Love-Gregory LD, Permutt MA, Hattersley AT, Frayling TM.

    Diabetes. 2004 Nov;53(11):3002-6.PMID: 15504983 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Effect of common polymorphisms in the HNF4alpha promoter on susceptibility to type 2 diabetes in the French Caucasian population.

    Vaxillaire M, Dina C, Lobbens S, Dechaume A, Vasseur-Delannoy V, Helbecque N, Charpentier G, Froguel P.

    Diabetologia. 2005 Mar;48(3):440-4. Epub 2005 Feb 25.PMID: 15735892 [PubMed - indexed for MEDLINE]Related articles

    3.

    A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor-4 alpha gene on chromosome 20q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an ashkenazi jewish population.

    Love-Gregory LD, Wasson J, Ma J, Jin CH, Glaser B, Suarez BK, Permutt MA.

    Diabetes. 2004 Apr;53(4):1134-40.PMID: 15047632 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Association testing of variants in the hepatocyte nuclear factor 4alpha gene with risk of type 2 diabetes in 7,883 people.

    Winckler W, Graham RR, de Bakker PI, Sun M, Almgren P, Tuomi T, Gaudet D, Hudson TJ, Ardlie KG, Daly MJ, Hirschhorn JN, Groop L, Altshuler D.

    Diabetes. 2005 Mar;54(3):886-92.PMID: 15734869 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Variants in hepatocyte nuclear factor 4alpha are modestly associated with type 2 diabetes in Pima Indians.

    Muller YL, Infante AM, Hanson RL, Love-Gregory L, Knowler W, Bogardus C, Baier LJ.

    Diabetes. 2005 Oct;54(10):3035-9.PMID: 16186411 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Rare variants identified in the HNF- 4 alpha beta-cell-specific promoter and alternative exon 1 lack biological significance in maturity onset diabetes of the young and young onset Type II diabetes.

    Mitchell SM, Vaxillaire M, Thomas H, Parrizas M, Benmezroua Y, Costa A, Hansen T, Owen KR, Tuomi T, Pirie F, Ryffel GU, Ferrer J, Froguel P, Hattersley AT, Frayling TM.

    Diabetologia. 2002 Sep;45(9):1344-8. Epub 2002 Jul 19.PMID: 12242469 [PubMed - indexed for MEDLINE]Related articles

    7.

    Hepatocyte nuclear factor-4alpha P2 promoter haplotypes are associated with type 2 diabetes in the Japanese population.

    Hara K, Horikoshi M, Kitazato H, Ito C, Noda M, Ohashi J, Froguel P, Tokunaga K, Tobe K, Nagai R, Kadowaki T.

    Diabetes. 2006 May;55(5):1260-4.PMID: 16644680 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Variation near the hepatocyte nuclear factor (HNF)-4alpha gene associates with type 2 diabetes in the Danish population.

    Hansen SK, Rose CS, Glümer C, Drivsholm T, Borch-Johnsen K, Jørgensen T, Pedersen O, Hansen T.

    Diabetologia. 2005 Mar;48(3):452-8. Epub 2005 Feb 25.PMID: 15735891 [PubMed - indexed for MEDLINE]Related articles

    9.

    Single nucleotide polymorphisms of the HNF4alpha gene are associated with the conversion to type 2 diabetes mellitus: the STOP-NIDDM trial.

    Andrulionyte L, Laukkanen O, Chiasson JL, Laakso M; STOP-NIDDM Study Group.

    J Mol Med. 2006 Aug;84(8):701-8. Epub 2006 Jul 13.PMID: 16838170 [PubMed - indexed for MEDLINE]Related articles

    10.

    No evidence for linkage at candidate type 2 diabetes susceptibility loci on chromosomes 12 and 20 in United Kingdom Caucasians.

    Frayling TM, McCarthy MI, Walker M, Levy JC, O'Rahilly S, Hitman GA, Rao PV, Bennett AJ, Jones EC, Menzel S, Ellard S, Hattersley AT.

    J Clin Endocrinol Metab. 2000 Feb;85(2):853-7.PMID: 10690901 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes.

    Silander K, Mohlke KL, Scott LJ, Peck EC, Hollstein P, Skol AD, Jackson AU, Deloukas P, Hunt S, Stavrides G, Chines PS, Erdos MR, Narisu N, Conneely KN, Li C, Fingerlin TE, Dhanjal SK, Valle TT, Bergman RN, Tuomilehto J, Watanabe RM, Boehnke M, Collins FS.

    Diabetes. 2004 Apr;53(4):1141-9.PMID: 15047633 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    A large-scale association analysis of common variation of the HNF1alpha gene with type 2 diabetes in the U.K. Caucasian population.

    Weedon MN, Owen KR, Shields B, Hitman G, Walker M, McCarthy MI, Hattersley AT, Frayling TM.

    Diabetes. 2005 Aug;54(8):2487-91.PMID: 16046319 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    P2 promoter variants of the hepatocyte nuclear factor 4alpha gene are associated with type 2 diabetes in Mexican Americans.

    Lehman DM, Richardson DK, Jenkinson CP, Hunt KJ, Dyer TD, Leach RJ, Arya R, Abboud HE, Blangero J, Duggirala R, Stern MP.

    Diabetes. 2007 Feb;56(2):513-7.PMID: 17259399 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    A common P2 promoter polymorphism of the hepatocyte nuclear factor-4alpha gene is associated with insulin secretion in non-obese Japanese with type 2 diabetes.

    Tokunaga A, Horikawa Y, Fukuda-Akita E, Okita K, Iwahashi H, Shimomura I, Takeda J, Yamagata K.

    Endocr J. 2008 Dec;55(6):999-1004. Epub 2008 Jul 24.PMID: 18654034 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Genetic analysis of HNF4A polymorphisms in Caucasian-American type 2 diabetes.

    Bagwell AM, Bento JL, Mychaleckyj JC, Freedman BI, Langefeld CD, Bowden DW.

    Diabetes. 2005 Apr;54(4):1185-90.PMID: 15793260 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    The role of the HNF4alpha enhancer in type 2 diabetes.

    Mitchell SM, Gloyn AL, Owen KR, Hattersley AT, Frayling TM.

    Mol Genet Metab. 2002 Jun;76(2):148-51.PMID: 12083813 [PubMed - indexed for MEDLINE]Related articles

    17.

    Analysis of the HNF4 alpha gene in Caucasian type II diabetic nephropathic patients.

    Price JA, Fossey SC, Sale MM, Brewer CS, Freedman BI, Wuerth JP, Bowden DW.

    Diabetologia. 2000 Mar;43(3):364-72.PMID: 10768098 [PubMed - indexed for MEDLINE]Related articles

    18.

    Variants in the hepatocyte nuclear factor-1alpha and -4alpha genes in Finnish and Chinese subjects with late-onset type 2 diabetes.

    Rissanen J, Wang H, Miettinen R, Kärkkäinen P, Kekäläinen P, Mykkänen L, Kuusisto J, Karhapää P, Niskanen L, Uusitupa M, Laakso M.

    Diabetes Care. 2000 Oct;23(10):1533-8.PMID: 11023148 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Polymorphisms in both promoters of hepatocyte nuclear factor 4-alpha are associated with type 2 diabetes in the Amish.

    Damcott CM, Hoppman N, Ott SH, Reinhart LJ, Wang J, Pollin TI, O'Connell JR, Mitchell BD, Shuldiner AR.

    Diabetes. 2004 Dec;53(12):3337-41.PMID: 15561969 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function.

    Hansen SK, Párrizas M, Jensen ML, Pruhova S, Ek J, Boj SF, Johansen A, Maestro MA, Rivera F, Eiberg H, Andel M, Lebl J, Pedersen O, Ferrer J, Hansen T.

    J Clin Invest. 2002 Sep;110(6):827-33.PMID: 12235114 [PubMed - indexed for MEDLINE]Related articlesFree article

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