PubMed

Intracellular stress signaling pathways activated during human islet preparation and following acute cytokine exposure.

Abdelli S, Ansite J, Roduit R, Borsello T, Matsumoto I, Sawada T, Allaman-Pillet N, Henry H, Beckmann JS, Hering BJ, Bonny C.

Diabetes. 2004 Nov;53(11):2815-23.PMID: 15504961 [PubMed - indexed for MEDLINE]Related articlesFree article

The c-Jun N-terminal kinase JNK participates in cytokine- and isolation stress-induced rat pancreatic islet apoptosis.

Abdelli S, Abderrahmani A, Hering BJ, Beckmann JS, Bonny C.

Diabetologia. 2007 Aug;50(8):1660-9. Epub 2007 Jun 9.PMID: 17558486 [PubMed - indexed for MEDLINE]Related articles

Suppression of the c-Jun N-terminal kinase pathway by 17beta-estradiol can preserve human islet functional mass from proinflammatory cytokine-induced destruction.

Eckhoff DE, Smyth CA, Eckstein C, Bilbao G, Young CJ, Thompson JA, Contreras JL.

Surgery. 2003 Aug;134(2):169-79.PMID: 12947315 [PubMed - indexed for MEDLINE]Related articles

Modulation of JNK and p38 stress activated protein kinases in isolated islets of Langerhans: insulin as an autocrine survival signal.

Paraskevas S, Aikin R, Maysinger D, Lakey JR, Cavanagh TJ, Agapitos D, Wang R, Rosenberg L.

Ann Surg. 2001 Jan;233(1):124-33.PMID: 11141234 [PubMed - indexed for MEDLINE]Related articlesFree article

Sustained activation of p38 mitogen-activated protein kinase and c-Jun N-terminal kinase pathways by hepatitis B virus X protein mediates apoptosis via induction of Fas/FasL and tumor necrosis factor (TNF) receptor 1/TNF-alpha expression.

Wang WH, Grégori G, Hullinger RL, Andrisani OM.

Mol Cell Biol. 2004 Dec;24(23):10352-65.PMID: 15542843 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: the requirement of extracellular signal-regulated kinase, p38, c-Jun N-terminal kinase and NF-kappaB pathways for the expression of proinflammatory cytokines and nitric oxide.

Zhu J, Krishnegowda G, Gowda DC.

J Biol Chem. 2005 Mar 4;280(9):8617-27. Epub 2004 Dec 15.PMID: 15611045 [PubMed - indexed for MEDLINE]Related articlesFree article

Nuclear factor-kappa B, p38, and stress-activated protein kinase mitogen-activated protein kinase signaling pathways regulate proinflammatory cytokines and apoptosis in human placental explants in response to oxidative stress: effects of antioxidant vitamins.

Cindrova-Davies T, Spasic-Boskovic O, Jauniaux E, Charnock-Jones DS, Burton GJ.

Am J Pathol. 2007 May;170(5):1511-20.PMID: 17456758 [PubMed - indexed for MEDLINE]Related articlesFree article

DIM stimulates IFNgamma gene expression in human breast cancer cells via the specific activation of JNK and p38 pathways.

Xue L, Firestone GL, Bjeldanes LF.

Oncogene. 2005 Mar 31;24(14):2343-53.PMID: 15735741 [PubMed - indexed for MEDLINE]Related articles

MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines.

Tournier C, Dong C, Turner TK, Jones SN, Flavell RA, Davis RJ.

Genes Dev. 2001 Jun 1;15(11):1419-26.PMID: 11390361 [PubMed - indexed for MEDLINE]Related articlesFree article

Flavopiridol suppresses tumor necrosis factor-induced activation of activator protein-1, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase (MAPK), p44/p42 MAPK, and Akt, inhibits expression of antiapoptotic gene products, and enhances apoptosis through cytochrome c release and caspase activation in human myeloid cells.

Takada Y, Sethi G, Sung B, Aggarwal BB.

Mol Pharmacol. 2008 May;73(5):1549-57. Epub 2008 Feb 20.PMID: 18287248 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin (IL)-4 and IL-13 up-regulate monocyte chemoattractant protein-1 expression in human bronchial epithelial cells: involvement of p38 mitogen-activated protein kinase, extracellular signal-regulated kinase 1/2 and Janus kinase-2 but not c-Jun NH2-terminal kinase 1/2 signalling pathways.

Ip WK, Wong CK, Lam CW.

Clin Exp Immunol. 2006 Jul;145(1):162-72.PMID: 16792687 [PubMed - indexed for MEDLINE]Related articlesFree article

The scaffold protein IB1/JIP-1 is a critical mediator of cytokine-induced apoptosis in pancreatic beta cells.

Haefliger JA, Tawadros T, Meylan L, Gurun SL, Roehrich ME, Martin D, Thorens B, Waeber G.

J Cell Sci. 2003 Apr 15;116(Pt 8):1463-9.PMID: 12640031 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcriptional regulation of lysophosphatidic acid-induced interleukin-8 expression and secretion by p38 MAPK and JNK in human bronchial epithelial cells.

Saatian B, Zhao Y, He D, Georas SN, Watkins T, Spannhake EW, Natarajan V.

Biochem J. 2006 Feb 1;393(Pt 3):657-68.PMID: 16197369 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt.

Størling J, Binzer J, Andersson AK, Züllig RA, Tonnesen M, Lehmann R, Spinas GA, Sandler S, Billestrup N, Mandrup-Poulsen T.

Diabetologia. 2005 Oct;48(10):2039-50. Epub 2005 Aug 25.PMID: 16132952 [PubMed - indexed for MEDLINE]Related articles

Inflammatory cytokines activate p38 MAPK to induce osteoprotegerin synthesis by MG-63 cells.

Pantouli E, Boehm MM, Koka S.

Biochem Biophys Res Commun. 2005 Apr 1;329(1):224-9.PMID: 15721297 [PubMed - indexed for MEDLINE]Related articles

Role of the mitogen-activated protein kinases in cytokine-mediated inhibition of insulin gene expression.

Chin-Chance CV, Newman MV, Aronovitz A, Blomeier H, Kruger J, Lee EJ, Lowe WL Jr.

J Investig Med. 2006 Apr;54(3):132-42.PMID: 16948396 [PubMed - indexed for MEDLINE]Related articles

Administration of ricin induces a severe inflammatory response via nonredundant stimulation of ERK, JNK, and P38 MAPK and provides a mouse model of hemolytic uremic syndrome.

Korcheva V, Wong J, Corless C, Iordanov M, Magun B.

Am J Pathol. 2005 Jan;166(1):323-39.PMID: 15632024 [PubMed - indexed for MEDLINE]Related articlesFree article

Interaction of Neisseria meningitidis with human brain microvascular endothelial cells: role of MAP- and tyrosine kinases in invasion and inflammatory cytokine release.

Sokolova O, Heppel N, Jägerhuber R, Kim KS, Frosch M, Eigenthaler M, Schubert-Unkmeir A.

Cell Microbiol. 2004 Dec;6(12):1153-66.PMID: 15527495 [PubMed - indexed for MEDLINE]Related articles

Complete inhibition of anisomycin and UV radiation but not cytokine induced JNK and p38 activation by an aryl-substituted dihydropyrrolopyrazole quinoline and mixed lineage kinase 7 small interfering RNA.

Wang X, Mader MM, Toth JE, Yu X, Jin N, Campbell RM, Smallwood JK, Christe ME, Chatterjee A, Goodson T Jr, Vlahos CJ, Matter WF, Bloem LJ.

J Biol Chem. 2005 May 13;280(19):19298-305. Epub 2005 Feb 28.PMID: 15737997 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell permeable peptide of JNK inhibitor prevents islet apoptosis immediately after isolation and improves islet graft function.

Noguchi H, Nakai Y, Matsumoto S, Kawaguchi M, Ueda M, Okitsu T, Iwanaga Y, Yonekawa Y, Nagata H, Minami K, Masui Y, Futaki S, Tanaka K.

Am J Transplant. 2005 Aug;5(8):1848-55.PMID: 15996231 [PubMed - indexed for MEDLINE]Related articles