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Physiological hyperinsulinemia in dogs augments access of macromolecules to insulin-sensitive tissues.
Ellmerer M, Kim SP, Hamilton-Wessler M, Hücking K, Kirkman E, Bergman RN.
Diabetes. 2004 Nov;53(11):2741-7.PMID: 15504953 [PubMed - indexed for MEDLINE]Related articlesFree article
Reduced access to insulin-sensitive tissues in dogs with obesity secondary to increased fat intake.
Ellmerer M, Hamilton-Wessler M, Kim SP, Huecking K, Kirkman E, Chiu J, Richey J, Bergman RN.
Diabetes. 2006 Jun;55(6):1769-75.PMID: 16731841 [PubMed - indexed for MEDLINE]Related articlesFree article
Physiological hyperinsulinemia has no detectable effect on access of macromolecules to insulin-sensitive tissues in healthy humans.
Weinhandl H, Pachler C, Mader JK, Ikeoka D, Mautner A, Falk A, Suppan M, Pieber TR, Ellmerer M.
Diabetes. 2007 Sep;56(9):2213-7. Epub 2007 Jun 29.PMID: 17601990 [PubMed - indexed for MEDLINE]Related articlesFree article
Dose-response relationship between lymph insulin and glucose uptake reveals enhanced insulin sensitivity of peripheral tissues.
Yang YJ, Hope I, Ader M, Poulin RA, Bergman RN.
Diabetes. 1992 Feb;41(2):241-53. Erratum in: Diabetes 1997 Apr;46(4):731. PMID: 1733816 [PubMed - indexed for MEDLINE]Related articles
Angiotensin II induces insulin resistance independent of changes in interstitial insulin.
Richey JM, Ader M, Moore D, Bergman RN.
Am J Physiol. 1999 Nov;277(5 Pt 1):E920-6.PMID: 10567021 [PubMed - indexed for MEDLINE]Related articlesFree article
Thoracic duct lymph. Relative contribution from splanchnic and muscle tissue.
Steil GM, Meador MA, Bergman RN.
Diabetes. 1993 May;42(5):720-31.PMID: 8482429 [PubMed - indexed for MEDLINE]Related articles
Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow.
Vincent MA, Dawson D, Clark AD, Lindner JR, Rattigan S, Clark MG, Barrett EJ.
Diabetes. 2002 Jan;51(1):42-8.PMID: 11756321 [PubMed - indexed for MEDLINE]Related articlesFree article
Extracellular glucose distribution is not altered by insulin: analysis of plasma and interstitial L-glucose kinetics.
Steil GM, Richey J, Kim JK, Wi JK, Rebrin K, Bergman RN, Youn JH.
Am J Physiol. 1996 Nov;271(5 Pt 1):E855-64.PMID: 8944672 [PubMed - indexed for MEDLINE]Related articles
Hyperinsulinemia rapidly increases human muscle microvascular perfusion but fails to increase muscle insulin clearance: evidence that a saturable process mediates muscle insulin uptake.
Eggleston EM, Jahn LA, Barrett EJ.
Diabetes. 2007 Dec;56(12):2958-63. Epub 2007 Aug 24.PMID: 17720897 [PubMed - indexed for MEDLINE]Related articlesFree article
Dynamics of glucose production and uptake are more closely related to insulin in hindlimb lymph than in thoracic duct lymph.
Poulin RA, Steil GM, Moore DM, Ader M, Bergman RN.
Diabetes. 1994 Feb;43(2):180-90.PMID: 8288041 [PubMed - indexed for MEDLINE]Related articles
Mode of transcapillary transport of insulin and insulin analog NN304 in dog hindlimb: evidence for passive diffusion.
Hamilton-Wessler M, Ader M, Dea MK, Moore D, Loftager M, Markussen J, Bergman RN.
Diabetes. 2002 Mar;51(3):574-82.PMID: 11872653 [PubMed - indexed for MEDLINE]Related articlesFree article
Decreased muscle capillary permeability surface area in type 2 diabetic subjects.
Gudbjörnsdóttir S, Sjöstrand M, Strindberg L, Lönnroth P.
J Clin Endocrinol Metab. 2005 Feb;90(2):1078-82. Epub 2004 Nov 9.PMID: 15536160 [PubMed - indexed for MEDLINE]Related articlesFree article
The role of the transcapillary insulin transport in the efficiency of insulin action: studies with glucose clamps and the minimal model.
Bergman RN, Yang YJ, Hope ID, Ader M.
Horm Metab Res Suppl. 1990;24:49-56. Review.PMID: 2272626 [PubMed - indexed for MEDLINE]Related articles
Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport.
Schwartz MW, Bergman RN, Kahn SE, Taborsky GJ Jr, Fisher LD, Sipols AJ, Woods SC, Steil GM, Porte D Jr.
J Clin Invest. 1991 Oct;88(4):1272-81.PMID: 1918377 [PubMed - indexed for MEDLINE]Related articlesFree article
Effects of acute hyperinsulinemia on insulin signal transduction and glucose transporters in ovine fetal skeletal muscle.
Anderson MS, Thamotharan M, Kao D, Devaskar SU, Qiao L, Friedman JE, Hay WW Jr.
Am J Physiol Regul Integr Comp Physiol. 2005 Feb;288(2):R473-81. Epub 2004 Nov 11.PMID: 15539611 [PubMed - indexed for MEDLINE]Related articles
Local methacholine but not bradykinin potentiates insulin-mediated glucose uptake in muscle in vivo by augmenting capillary recruitment.
Mahajan H, Richards SM, Rattigan S, Clark MG.
Diabetologia. 2004 Dec;47(12):2226-34. Epub 2004 Dec 16.PMID: 15602653 [PubMed - indexed for MEDLINE]Related articles
Measurement of interstitial insulin in human adipose and muscle tissue under moderate hyperinsulinemia by means of direct interstitial access.
Bodenlenz M, Schaupp LA, Druml T, Sommer R, Wutte A, Schaller HC, Sinner F, Wach P, Pieber TR.
Am J Physiol Endocrinol Metab. 2005 Aug;289(2):E296-300. Epub 2005 Mar 15.PMID: 15769794 [PubMed - indexed for MEDLINE]Related articlesFree article
Effects of Intrabrachial metacholine infusion on muscle capillary recruitment and forearm glucose uptake during physiological hyperinsulinemia in obese, insulin-resistant individuals.
Murdolo G, Sjöstrand M, Strindberg L, Gudbjörnsdóttir S, Lind L, Lönnroth P, Jansson PA.
J Clin Endocrinol Metab. 2008 Jul;93(7):2764-73. Epub 2008 May 6.PMID: 18460559 [PubMed - indexed for MEDLINE]Related articlesFree article
Paradoxical changes of muscle glutamine release during hyperinsulinemia euglycemia and hypoglycemia in humans: further evidence for the glucose-glutamine cycle.
Meyer C, Woerle HJ, Gerich J.
Metabolism. 2004 Sep;53(9):1208-14.PMID: 15334386 [PubMed - indexed for MEDLINE]Related articles
Splanchnic and systemic hemodynamic effects of sustained euglycemic hyperinsulinemia in rats.
Hilzenrat N, Yaari A, Maislos M, Sikuler E.
Scand J Clin Lab Invest. 2001;61(5):383-8.PMID: 11569485 [PubMed - indexed for MEDLINE]Related articles
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