PubMed

Granzyme B; the chalk-mark of a cytotoxic lymphocyte.

Waterhouse NJ, Sedelies KA, Clarke CJ.

J Transl Med. 2004 Oct 25;2(1):36.PMID: 15500699 [PubMed - as supplied by publisher]Related articlesFree article

Active and zymogen forms of granzyme B are constitutively released from cytotoxic lymphocytes in the absence of target cell engagement.

Prakash MD, Bird CH, Bird PI.

Immunol Cell Biol. 2009 Mar-Apr;87(3):249-54. Epub 2008 Dec 16.PMID: 19079360 [PubMed - indexed for MEDLINE]Related articles

Evaluating antigen-specific cytotoxic T lymphocyte responses by a novel mouse granzyme B ELISPOT assay.

Ewen CL, Rong J, Kokaji AI, Bleackley RC, Kane KP.

J Immunol Methods. 2006 Jan 20;308(1-2):156-66. Epub 2005 Dec 5.PMID: 16375915 [PubMed - indexed for MEDLINE]Related articles

Granzyme B-induced cell death involves induction of p53 tumor suppressor gene and its activation in tumor target cells.

Meslin F, Thiery J, Richon C, Jalil A, Chouaib S.

J Biol Chem. 2007 Nov 9;282(45):32991-9. Epub 2007 Sep 13.PMID: 17855337 [PubMed - indexed for MEDLINE]Related articlesFree article

Application of the granzyme B ELISPOT assay for monitoring cancer vaccine trials.

Shafer-Weaver K, Rosenberg S, Strobl S, Gregory Alvord W, Baseler M, Malyguine A.

J Immunother. 2006 May-Jun;29(3):328-35.PMID: 16699376 [PubMed - indexed for MEDLINE]Related articles

Possible key role of granzyme B in keratoacanthoma regression.

Batinac T, Zamolo G, Coklo M, Hadzisejdic I.

Med Hypotheses. 2006;66(6):1129-32. Epub 2006 Feb 23.PMID: 16497444 [PubMed - indexed for MEDLINE]Related articles

Granule-mediated killing by granzyme B and perforin requires a mannose 6-phosphate receptor and is augmented by cell surface heparan sulfate.

Veugelers K, Motyka B, Goping IS, Shostak I, Sawchuk T, Bleackley RC.

Mol Biol Cell. 2006 Feb;17(2):623-33. Epub 2005 Nov 9.PMID: 16280358 [PubMed - indexed for MEDLINE]Related articlesFree article

Decrease of cytotoxic T cells in allergic asthma correlates with total serum immunglobulin E.

Bratke K, Haupt F, Kuepper M, Bade B, Faehndrich S, Luttmann W, Virchow JC Jr.

Allergy. 2006 Nov;61(11):1351-7.PMID: 17002713 [PubMed - indexed for MEDLINE]Related articles

Role of Bid-induced mitochondrial outer membrane permeabilization in granzyme B-induced apoptosis.

Waterhouse NJ, Sedelies KA, Trapani JA.

Immunol Cell Biol. 2006 Feb;84(1):72-8. Review.PMID: 16405654 [PubMed - indexed for MEDLINE]Related articles

Selective chemical functional probes of granzymes A and B reveal granzyme B is a major effector of natural killer cell-mediated lysis of target cells.

Mahrus S, Craik CS.

Chem Biol. 2005 May;12(5):567-77.PMID: 15911377 [PubMed - indexed for MEDLINE]Related articles

The granzyme B and interferon-gamma enzyme-linked immunospot assay as alternatives for cytotoxic T-lymphocyte precursor frequency after renal transplantation.

van Besouw NM, Zuijderwijk JM, de Kuiper P, Ijzermans JN, Weimar W, van der Mast BJ.

Transplantation. 2005 May 15;79(9):1062-6.PMID: 15880044 [PubMed - indexed for MEDLINE]Related articles

Granzyme B-mediated death of pancreatic beta-cells requires the proapoptotic BH3-only molecule bid.

Estella E, McKenzie MD, Catterall T, Sutton VR, Bird PI, Trapani JA, Kay TW, Thomas HE.

Diabetes. 2006 Aug;55(8):2212-9.PMID: 16873683 [PubMed - indexed for MEDLINE]Related articlesFree article

Vesicle-associated membrane protein 7 (VAMP-7) is essential for target cell killing in a natural killer cell line.

Marcet-Palacios M, Odemuyiwa SO, Coughlin JJ, Garofoli D, Ewen C, Davidson CE, Ghaffari M, Kane KP, Lacy P, Logan MR, Befus AD, Bleackley RC, Moqbel R.

Biochem Biophys Res Commun. 2008 Feb 15;366(3):617-23. Epub 2007 Nov 26.PMID: 18042464 [PubMed - indexed for MEDLINE]Related articles

The cytotoxic lymphocyte protease, granzyme B, targets the cytoskeleton and perturbs microtubule polymerization dynamics.

Adrain C, Duriez PJ, Brumatti G, Delivani P, Martin SJ.

J Biol Chem. 2006 Mar 24;281(12):8118-25. Epub 2006 Jan 16.PMID: 16415351 [PubMed - indexed for MEDLINE]Related articlesFree article

Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage.

Grujic M, Braga T, Lukinius A, Eloranta ML, Knight SD, Pejler G, Abrink M.

J Biol Chem. 2005 Sep 30;280(39):33411-8. Epub 2005 Jul 26.PMID: 16046402 [PubMed - indexed for MEDLINE]Related articlesFree article

Increase in activated CD8+ T lymphocytes expressing perforin and granzyme B correlates with disease activity in patients with systemic lupus erythematosus.

Blanco P, Pitard V, Viallard JF, Taupin JL, Pellegrin JL, Moreau JF.

Arthritis Rheum. 2005 Jan;52(1):201-11.PMID: 15641052 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of granzyme B and T cell cytotoxic capacity by IL-2 or IL-15 without antigens: multiclonal responses that are extremely lytic if triggered and short-lived after cytokine withdrawal.

Tamang DL, Redelman D, Alves BN, Vollger L, Bethley C, Hudig D.

Cytokine. 2006 Nov;36(3-4):148-59. Epub 2006 Dec 22.PMID: 17188506 [PubMed - indexed for MEDLINE]Related articlesFree article

Granzyme C supports efficient CTL-mediated killing late in primary alloimmune responses.

Getachew Y, Stout-Delgado H, Miller BC, Thiele DL.

J Immunol. 2008 Dec 1;181(11):7810-7.PMID: 19017970 [PubMed - indexed for MEDLINE]Related articlesFree article

Nucleophosmin is cleaved and inactivated by the cytotoxic granule protease granzyme M during natural killer cell-mediated killing.

Cullen SP, Afonina IS, Donadini R, Lüthi AU, Medema JP, Bird PI, Martin SJ.

J Biol Chem. 2009 Feb 20;284(8):5137-47. Epub 2008 Dec 22.PMID: 19103589 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of granzyme B expression in T-cell receptor/CD28-stimulated human regulatory T cells is suppressed by inhibitors of the PI3K-mTOR pathway.

Efimova OV, Kelley TW.

BMC Immunol. 2009 Nov 22;10:59.PMID: 19930596 [PubMed - in process]Related articlesFree article