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Aldose reductase inhibition by AS-3201 in sural nerve from patients with diabetic sensorimotor polyneuropathy.

Bril V, Buchanan RA.

Diabetes Care. 2004 Oct;27(10):2369-75.PMID: 15451902 [PubMed - indexed for MEDLINE]Related articlesFree article

Ranirestat for the management of diabetic sensorimotor polyneuropathy.

Bril V, Hirose T, Tomioka S, Buchanan R; Ranirestat Study Group.

Diabetes Care. 2009 Jul;32(7):1256-60. Epub 2009 Apr 14.PMID: 19366965 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term effects of ranirestat (AS-3201) on peripheral nerve function in patients with diabetic sensorimotor polyneuropathy.

Bril V, Buchanan RA.

Diabetes Care. 2006 Jan;29(1):68-72.PMID: 16373898 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycemic control is related to the electrophysiologic severity of diabetic peripheral sensorimotor polyneuropathy.

Tkac I, Bril V.

Diabetes Care. 1998 Oct;21(10):1749-52.PMID: 9773742 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of hyperglycemia and the aldose reductase inhibitor tolrestat on sural nerve biochemistry and morphometry in advanced diabetic peripheral polyneuropathy. The Tolrestat Study Group.

Sima AA, Greene DA, Brown MB, Hohman TC, Hicks D, Graepel GJ, Bochenek WJ, Beg M, Gonen B.

J Diabetes Complications. 1993 Jul-Sep;7(3):157-69.PMID: 8343610 [PubMed - indexed for MEDLINE]Related articles

Sural nerve sorbitol in patients with diabetic sensorimotor polyneuropathy.

Bril V, Ono Y, Buchanan RA.

Diabetes Care. 2004 May;27(5):1160-3. Review.PMID: 15111538 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment of diabetic polyneuropathy with the antioxidant thioctic acid (alpha-lipoic acid): a two year multicenter randomized double-blind placebo-controlled trial (ALADIN II). Alpha Lipoic Acid in Diabetic Neuropathy.

Reljanovic M, Reichel G, Rett K, Lobisch M, Schuette K, Möller W, Tritschler HJ, Mehnert H.

Free Radic Res. 1999 Sep;31(3):171-9.PMID: 10499773 [PubMed - indexed for MEDLINE]Related articles

Effect of aldose reductase inhibition on nerve conduction and morphometry in diabetic neuropathy. Zenarestat Study Group.

Greene DA, Arezzo JC, Brown MB.

Neurology. 1999 Aug 11;53(3):580-91. Erratum in: Neurology 2001 Apr 24;56(8):1124. PMID: 10449124 [PubMed - indexed for MEDLINE]Related articles

Progression of distal symmetric polyneuropathy during diabetes mellitus: clinical, neurophysiological, haemorheological changes and self-rating scales of patients.

Husstedt IW, Grotemeyer KH, Evers S, Staschewski F, Wertelewski R.

Eur Neurol. 1997;37(2):90-4.PMID: 9058063 [PubMed - indexed for MEDLINE]Related articles

Regeneration and repair of myelinated fibers in sural-nerve biopsy specimens from patients with diabetic neuropathy treated with sorbinil.

Sima AA, Bril V, Nathaniel V, McEwen TA, Brown MB, Lattimer SA, Greene DA.

N Engl J Med. 1988 Sep 1;319(9):548-55.PMID: 3136331 [PubMed - indexed for MEDLINE]Related articles

Overt diabetic neuropathy: repair of axo-glial dysjunction and axonal atrophy by aldose reductase inhibition and its correlation to improvement in nerve conduction velocity.

Sima AA, Prashar A, Nathaniel V, Bril V, Werb MR, Greene DA.

Diabet Med. 1993 Mar;10(2):115-21.PMID: 8458187 [PubMed - indexed for MEDLINE]Related articles

Ranirestat (AS-3201), a potent aldose reductase inhibitor, reduces sorbitol levels and improves motor nerve conduction velocity in streptozotocin-diabetic rats.

Matsumoto T, Ono Y, Kurono M, Kuromiya A, Nakamura K, Bril V.

J Pharmacol Sci. 2008 Jul;107(3):231-7.PMID: 18635918 [PubMed - indexed for MEDLINE]Related articlesFree article

Validation of a novel point-of-care nerve conduction device for the detection of diabetic sensorimotor polyneuropathy.

Perkins BA, Grewal J, Ng E, Ngo M, Bril V.

Diabetes Care. 2006 Sep;29(9):2023-7.PMID: 16936147 [PubMed - indexed for MEDLINE]Related articlesFree article

[Effects of the aldose reductase inhibitor on diabetic polyneuropathy--the efficacy of F wave measurement]

Shimada H, Miki T, Kyogoku I, Kawagishi T, Inaba M, Okuno Y, Nishizawa Y, Morii H.

No To Shinkei. 1998 Sep;50(9):817-20. Japanese. PMID: 9789304 [PubMed - indexed for MEDLINE]Related articles

Withdrawal of the aldose reductase inhibitor tolrestat in patients with diabetic neuropathy: effect on nerve function. The Tolrestat Study Group.

Santiago JV, Snksen PH, Boulton AJ, Macleod A, Beg M, Bochenek W, Graepel GJ, Gonen B.

J Diabetes Complications. 1993 Jul-Sep;7(3):170-8.PMID: 8343611 [PubMed - indexed for MEDLINE]Related articles

Clinical efficacy of fidarestat, a novel aldose reductase inhibitor, for diabetic peripheral neuropathy: a 52-week multicenter placebo-controlled double-blind parallel group study.

Hotta N, Toyota T, Matsuoka K, Shigeta Y, Kikkawa R, Kaneko T, Takahashi A, Sugimura K, Koike Y, Ishii J, Sakamoto N; SNK-860 Diabetic Neuropathy Study Group.

Diabetes Care. 2001 Oct;24(10):1776-82. Erratum in: Diabetes Care 2002 Feb;25(2):413-4. PMID: 11574441 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy and safety of recombinant human nerve growth factor in patients with diabetic polyneuropathy: A randomized controlled trial. rhNGF Clinical Investigator Group.

Apfel SC, Schwartz S, Adornato BT, Freeman R, Biton V, Rendell M, Vinik A, Giuliani M, Stevens JC, Barbano R, Dyck PJ.

JAMA. 2000 Nov 1;284(17):2215-21.PMID: 11056593 [PubMed - indexed for MEDLINE]Related articlesFree article

C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy.

Ekberg K, Brismar T, Johansson BL, Lindström P, Juntti-Berggren L, Norrby A, Berne C, Arnqvist HJ, Bolinder J, Wahren J.

Diabetes Care. 2007 Jan;30(1):71-6.PMID: 17192336 [PubMed - indexed for MEDLINE]Related articlesFree article

One-year treatment with the aldose reductase inhibitor, ponalrestat, in diabetic neuropathy.

Ziegler D, Mayer P, Rathmann W, Gries FA.

Diabetes Res Clin Pract. 1991 Oct;14(1):63-73.PMID: 1748064 [PubMed - indexed for MEDLINE]Related articles

Validation of the Toronto Clinical Scoring System for diabetic polyneuropathy.

Bril V, Perkins BA.

Diabetes Care. 2002 Nov;25(11):2048-52.PMID: 12401755 [PubMed - indexed for MEDLINE]Related articlesFree article