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Pancreatic beta-cell function and immune responses to insulin after administration of intranasal insulin to humans at risk for type 1 diabetes.

Harrison LC, Honeyman MC, Steele CE, Stone NL, Sarugeri E, Bonifacio E, Couper JJ, Colman PG.

Diabetes Care. 2004 Oct;27(10):2348-55.PMID: 15451899 [PubMed - indexed for MEDLINE]Related articlesFree article

First-phase insulin response in young healthy children at genetic and immunological risk for Type I diabetes.

Keskinen P, Korhonen S, Kupila A, Veijola R, Erkkilä S, Savolainen H, Arvilommi P, Simell T, Ilonen J, Knip M, Simell O.

Diabetologia. 2002 Dec;45(12):1639-48. Epub 2002 Oct 30.PMID: 12488953 [PubMed - indexed for MEDLINE]Related articles

Linear loss of insulin secretory capacity during the last six months preceding IDDM. No effect of antiedematous therapy with ketotifen.

Böhmer KP, Kolb H, Kuglin B, Zielasek J, Hübinger A, Lampeter EF, Weber B, Kolb-Bachofen V, Jastram HU, Bertrams J, et al.

Diabetes Care. 1994 Feb;17(2):138-41.PMID: 8137684 [PubMed - indexed for MEDLINE]Related articles

Delay of type I diabetes in high risk, first degree relatives by parenteral antigen administration: the Schwabing Insulin Prophylaxis Pilot Trial.

Füchtenbusch M, Rabl W, Grassl B, Bachmann W, Standl E, Ziegler AG.

Diabetologia. 1998 May;41(5):536-41.PMID: 9628270 [PubMed - indexed for MEDLINE]Related articles

Preservation of C-peptide secretion in subjects at high risk of developing type 1 diabetes mellitus--a new surrogate measure of non-progression?

Schatz D, Cuthbertson D, Atkinson M, Salzler MC, Winter W, Muir A, Silverstein J, Cook R, Maclaren N, She JX, Greenbaum C, Krischer J.

Pediatr Diabetes. 2004 Jun;5(2):72-9.PMID: 15189492 [PubMed - indexed for MEDLINE]Related articles

Predictive value of intravenous glucose tolerance test insulin secretion less than or greater than the first percentile in islet cell antibody positive relatives of type 1 (insulin-dependent) diabetic patients.

Vardi P, Crisa L, Jackson RA.

Diabetologia. 1991 Feb;34(2):93-102.PMID: 2065854 [PubMed - indexed for MEDLINE]Related articles

Quantification of human cytoplasmic islet-cell antibodies which cross-react with mouse pancreas: a follow-up study in type 1 (insulin-dependent) diabetic patients and in first-degree relatives.

Saï P, Elmansour A, Audrain M, Charbonnel B, Bardet S.

Diabetologia. 1993 Aug;36(8):778-84.PMID: 8405747 [PubMed - indexed for MEDLINE]Related articles

Risk of type 1 diabetes development in children with incidental hyperglycemia: A multicenter Italian study.

Lorini R, Alibrandi A, Vitali L, Klersy C, Martinetti M, Betterle C, d'Annunzio G, Bonifacio E; Pediatric Italian Study Group of Prediabetes.

Diabetes Care. 2001 Jul;24(7):1210-6.PMID: 11423504 [PubMed - indexed for MEDLINE]Related articlesFree article

Oral insulin administration and residual beta-cell function in recent-onset type 1 diabetes: a multicentre randomised controlled trial. Diabète Insuline Orale group.

Chaillous L, Lefèvre H, Thivolet C, Boitard C, Lahlou N, Atlan-Gepner C, Bouhanick B, Mogenet A, Nicolino M, Carel JC, Lecomte P, Maréchaud R, Bougnères P, Charbonnel B, Saï P.

Lancet. 2000 Aug 12;356(9229):545-9.PMID: 10950231 [PubMed - indexed for MEDLINE]Related articles

Effects of insulin administration on beta-cell function in subjects at high risk for type I diabetes mellitus.

Rodríguez-Villar C, Conget I, González-Clemente JM, Vidal J, Navarro P, Casamitjana R, Gomis R.

Metabolism. 1996 Jul;45(7):873-5.PMID: 8692024 [PubMed - indexed for MEDLINE]Related articles

Intranasally administered insulin intended for prevention of type 1 diabetes--a safety study in healthy adults.

Kupila A, Sipilä J, Keskinen P, Simell T, Knip M, Pulkki K, Simell O.

Diabetes Metab Res Rev. 2003 Sep-Oct;19(5):415-20.PMID: 12951650 [PubMed - indexed for MEDLINE]Related articles

Insulin autoantibodies as determined by competitive radiobinding assay are positively correlated with impaired beta-cell function--the Ulm-Frankfurt Population Study.

Yassin N, Seissler J, Glück M, Boehm BO, Heinze E, Pfeiffer EF, Scherbaum WA.

Klin Wochenschr. 1991 Oct 18;69(16):736-41.PMID: 1762378 [PubMed - indexed for MEDLINE]Related articles

Effects of insulin administration in a group of high-risk, non-diabetic, first-degree relatives of Type 1 diabetic patients: an open pilot trial.

Rodríguez-Villar C, Conget I, Casamitjana R, Ercilla G, Gomis R.

Diabet Med. 1999 Feb;16(2):160-3.PMID: 10229311 [PubMed - indexed for MEDLINE]Related articles

Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1).

Butty V, Campbell C, Mathis D, Benoist C; DPT-1 Study Group.

Diabetes. 2008 Sep;57(9):2348-59. Epub 2008 Jun 12.PMID: 18556337 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of standard nicotinamide in the prevention of type 1 diabetes in first degree relatives of persons with type 1 diabetes.

Cabrera-Rode E, Molina G, Arranz C, Vera M, González P, Suárez R, Prieto M, Padrón S, León R, Tillan J, García I, Tiberti C, Rodríguez OM, Gutiérrez A, Fernández T, Govea A, Hernández J, Chiong D, Domínguez E, Di Mario U, Díaz-Díaz O, Díaz-Horta O.

Autoimmunity. 2006 Jun;39(4):333-40.PMID: 16891222 [PubMed - indexed for MEDLINE]Related articles

Antibodies to the M(r) 64,000 (64K) protein in islet cell antibody positive non-diabetic individuals indicate high risk for impaired beta-cell function.

Seissler J, Hering B, Richter W, Glück M, Yassin N, Bretzel RG, Boehm BO, Federlin K, Scherbaum WA.

Diabetologia. 1992 Jun;35(6):550-4.PMID: 1612228 [PubMed - indexed for MEDLINE]Related articles

The natural history of pre-type 1 (insulin-dependent) diabetes mellitus in patients with autoimmune endocrine diseases.

Betterle C, Presotto F, Magrin L, Pedini B, Moro L, Caretto A, Zanchetta R.

Diabetologia. 1994 Jan;37(1):95-103.PMID: 8150236 [PubMed - indexed for MEDLINE]Related articles

No effect of oral insulin on residual beta-cell function in recent-onset type I diabetes (the IMDIAB VII). IMDIAB Group.

Pozzilli P, Pitocco D, Visalli N, Cavallo MG, Buzzetti R, Crinò A, Spera S, Suraci C, Multari G, Cervoni M, Manca Bitti ML, Matteoli MC, Marietti G, Ferrazzoli F, Cassone Faldetta MR, Giordano C, Sbriglia M, Sarugeri E, Ghirlanda G.

Diabetologia. 2000 Aug;43(8):1000-4.PMID: 10990077 [PubMed - indexed for MEDLINE]Related articles

Cyclosporine delays but does not prevent clinical onset in glucose intolerant pre-type 1 diabetic children.

Carel JC, Boitard C, Eisenbarth G, Bach JF, Bougnères PF.

J Autoimmun. 1996 Dec;9(6):739-45.PMID: 9115576 [PubMed - indexed for MEDLINE]Related articles

Slow metabolic deterioration towards diabetes in islet cell antibody positive patients with autoimmune polyendocrine disease.

Wagner R, Genovese S, Bosi E, Becker F, Bingley PJ, Bonifacio E, Miles KA, Christie MR, Bottazzo GF, Gale EA.

Diabetologia. 1994 Apr;37(4):365-71.PMID: 8063036 [PubMed - indexed for MEDLINE]Related articles