PubMed

Promotion of beta-cell differentiation by conophylline in fetal and neonatal rat pancreas.

Ogata T, Li L, Yamada S, Yamamoto Y, Tanaka Y, Takei I, Umezawa K, Kojima I.

Diabetes. 2004 Oct;53(10):2596-602.PMID: 15448089 [PubMed - indexed for MEDLINE]Related articlesFree article

Conophylline: a novel differentiation inducer for pancreatic beta cells.

Kojima I, Umezawa K.

Int J Biochem Cell Biol. 2006;38(5-6):923-30. Epub 2005 Oct 26. Review.PMID: 16337165 [PubMed - indexed for MEDLINE]Related articles

Activin A and betacellulin: effect on regeneration of pancreatic beta-cells in neonatal streptozotocin-treated rats.

Li L, Yi Z, Seno M, Kojima I.

Diabetes. 2004 Mar;53(3):608-15.PMID: 14988244 [PubMed - indexed for MEDLINE]Related articlesFree article

Conophylline and betacellulin-delta4: an effective combination of differentiation factors for pancreatic beta cells.

Kitamura R, Ogata T, Tanaka Y, Motoyoshi K, Seno M, Takei I, Umezawa K, Kojima I.

Endocr J. 2007 Apr;54(2):255-64. Epub 2007 Feb 16.PMID: 17303930 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of insulin production in rat pancreatic acinar carcinoma cells by conophylline.

Umezawa K, Hiroki A, Kawakami M, Naka H, Takei I, Ogata T, Kojima I, Koyano T, Kowithayakorn T, Pang HS, Kam TS.

Biomed Pharmacother. 2003 Oct;57(8):341-50.PMID: 14568228 [PubMed - indexed for MEDLINE]Related articles

Antidiabetic effect of orally administered conophylline-containing plant extract on streptozotocin-treated and Goto-Kakizaki rats.

Fujii M, Takei I, Umezawa K.

Biomed Pharmacother. 2009 Feb 4. [Epub ahead of print]PMID: 19217246 [PubMed - as supplied by publisher]Related articles

Duct- to islet-cell differentiation and islet growth in the pancreas of duct-ligated adult rats.

Wang RN, Klöppel G, Bouwens L.

Diabetologia. 1995 Dec;38(12):1405-11.PMID: 8786013 [PubMed - indexed for MEDLINE]Related articles

Keratinocyte growth factor and beta-cell differentiation in human fetal pancreatic endocrine precursor cells.

Movassat J, Beattie GM, Lopez AD, Portha B, Hayek A.

Diabetologia. 2003 Jun;46(6):822-9. Epub 2003 Jun 11.PMID: 12802496 [PubMed - indexed for MEDLINE]Related articles

Betacellulin and activin A coordinately convert amylase-secreting pancreatic AR42J cells into insulin-secreting cells.

Mashima H, Ohnishi H, Wakabayashi K, Mine T, Miyagawa J, Hanafusa T, Seno M, Yamada H, Kojima I.

J Clin Invest. 1996 Apr 1;97(7):1647-54.PMID: 8601630 [PubMed - indexed for MEDLINE]Related articlesFree article

Early development of beta-cells is impaired in the GK rat model of type 2 diabetes.

Miralles F, Portha B.

Diabetes. 2001 Feb;50 Suppl 1:S84-8.PMID: 11272209 [PubMed - indexed for MEDLINE]Related articles

Up-regulation of the expression of activins in the pancreatic duct by reduction of the beta-cell mass.

Zhang YQ, Zhang H, Maeshima A, Kurihara H, Miyagawa J, Takeuchi T, Kojima I.

Endocrinology. 2002 Sep;143(9):3540-7.PMID: 12193568 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatocyte growth factor regulates proliferation and differentiation of epithelial monolayers derived from islets of postnatal rat pancreas.

Wang R, Yashpal N, Bacchus F, Li J.

J Endocrinol. 2004 Oct;183(1):163-71.PMID: 15525584 [PubMed - indexed for MEDLINE]Related articlesFree article

Fetal and neonatal rat pancreas in organ culture: age-related effects of corticosterone on the development of the islet cells.

McEvoy RC.

Am J Anat. 1980 Mar;157(3):319-27.PMID: 6105822 [PubMed - indexed for MEDLINE]Related articles

Regulation of pancreatic endocrine cell differentiation by sulphated proteoglycans.

Zertal-Zidani S, Bounacer A, Scharfmann R.

Diabetologia. 2007 Mar;50(3):585-95. Epub 2007 Jan 13.PMID: 17221210 [PubMed - indexed for MEDLINE]Related articles

Glucocorticoids suppress beta-cell development and induce hepatic metaplasia in embryonic pancreas.

Shen CN, Seckl JR, Slack JM, Tosh D.

Biochem J. 2003 Oct 1;375(Pt 1):41-50.PMID: 14509268 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of H1-calponin in pancreatic AR42J cell differentiation into insulin-producing cells.

Morioka T, Koyama H, Yamamura H, Tanaka S, Fukumoto S, Emoto M, Mizuguchi H, Hayakawa T, Kojima I, Takahashi K, Nishizawa Y.

Diabetes. 2003 Mar;52(3):760-6.PMID: 12606518 [PubMed - indexed for MEDLINE]Related articlesFree article

Exogenous activin increases the proportion of insulin cells in the developing chick pancreas in culture.

Penny C, Kramer B.

Cell Biol Int. 2002;26(12):1057-64.PMID: 12468381 [PubMed - indexed for MEDLINE]Related articles

A simple method to induce differentiation of murine bone marrow mesenchymal cells to insulin-producing cells using conophylline and betacellulin-delta4.

Hisanaga E, Park KY, Yamada S, Hashimoto H, Takeuchi T, Mori M, Seno M, Umezawa K, Takei I, Kojima I.

Endocr J. 2008 Jul;55(3):535-43. Epub 2008 May 15.PMID: 18480554 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of activin signaling induces pancreatic epithelial cell expansion and diminishes terminal differentiation of pancreatic beta-cells.

Zhang YQ, Cleary MM, Si Y, Liu G, Eto Y, Kritzik M, Dabernat S, Kayali AG, Sarvetnick N.

Diabetes. 2004 Aug;53(8):2024-33.PMID: 15277382 [PubMed - indexed for MEDLINE]Related articlesFree article

Low-protein diet during early life causes a reduction in the frequency of cells immunopositive for nestin and CD34 in both pancreatic ducts and islets in the rat.

Joanette EA, Reusens B, Arany E, Thyssen S, Remacle RC, Hill DJ.

Endocrinology. 2004 Jun;145(6):3004-13. Epub 2004 Mar 24.PMID: 15044374 [PubMed - indexed for MEDLINE]Related articlesFree article