PubMed

Local activation of dendritic cells leads to insulitis and development of insulin-dependent diabetes in transgenic mice expressing CD154 on the pancreatic beta-cells.

Haase C, Skak K, Michelsen BK, Markholst H.

Diabetes. 2004 Oct;53(10):2588-95.PMID: 15448088 [PubMed - indexed for MEDLINE]Related articlesFree article

Neither B lymphocytes nor antibodies directed against self antigens of the islets of Langerhans are required for development of virus-induced autoimmune diabetes.

Holz A, Dyrberg T, Hagopian W, Homann D, von Herrath M, Oldstone MB.

J Immunol. 2000 Nov 15;165(10):5945-53.PMID: 11067957 [PubMed - indexed for MEDLINE]Related articlesFree article

CD154-dependent priming of diabetogenic CD4(+) T cells dissociated from activation of antigen-presenting cells.

Amrani A, Serra P, Yamanouchi J, Han B, Thiessen S, Verdaguer J, Santamaria P.

Immunity. 2002 May;16(5):719-32.PMID: 12049723 [PubMed - indexed for MEDLINE]Related articles

CD40 is required for development of islet inflammation in the RIP-CD154 transgenic mouse model of type 1 diabetes.

Haase C, Markholst H.

Ann N Y Acad Sci. 2007 Jun;1107:373-9.PMID: 17804565 [PubMed - indexed for MEDLINE]Related articles

A crucial role of CD4 T cells as a functional source of CD154 in the initiation of insulin-dependent diabetes mellitus in the non-obese diabetic mouse.

Eshima K, Mora C, Wong FS, Green EA, Grewal IS, Flavell RA.

Int Immunol. 2003 Mar;15(3):351-7.PMID: 12618479 [PubMed - indexed for MEDLINE]Related articlesFree article

Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice.

Tarbell KV, Petit L, Zuo X, Toy P, Luo X, Mqadmi A, Yang H, Suthanthiran M, Mojsov S, Steinman RM.

J Exp Med. 2007 Jan 22;204(1):191-201. Epub 2007 Jan 8.PMID: 17210729 [PubMed - indexed for MEDLINE]Related articlesFree article

Cross-priming of diabetogenic T cells dissociated from CTL-induced shedding of beta cell autoantigens.

Yamanouchi J, Verdaguer J, Han B, Amrani A, Serra P, Santamaria P.

J Immunol. 2003 Dec 15;171(12):6900-9.PMID: 14662897 [PubMed - indexed for MEDLINE]Related articlesFree article

Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes.

Höglund P, Mintern J, Waltzinger C, Heath W, Benoist C, Mathis D.

J Exp Med. 1999 Jan 18;189(2):331-9.PMID: 9892615 [PubMed - indexed for MEDLINE]Related articlesFree article

Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue.

Ludewig B, Odermatt B, Landmann S, Hengartner H, Zinkernagel RM.

J Exp Med. 1998 Oct 19;188(8):1493-501.PMID: 9782126 [PubMed - indexed for MEDLINE]Related articlesFree article

Local production of human IL-6 promotes insulitis but retards the onset of insulin-dependent diabetes mellitus in non-obese diabetic mice.

DiCosmo BF, Picarella D, Flavell RA.

Int Immunol. 1994 Dec;6(12):1829-37.PMID: 7696203 [PubMed - indexed for MEDLINE]Related articles

The regulatory role of DR4 in a spontaneous diabetes DQ8 transgenic model.

Wen L, Chen NY, Tang J, Sherwin R, Wong FS.

J Clin Invest. 2001 Apr;107(7):871-80.PMID: 11285306 [PubMed - indexed for MEDLINE]Related articlesFree article

Low dose streptozotocin-induced diabetes in rat insulin promoter-mCD80-transgenic mice is T cell autoantigen-specific and CD28 dependent.

Pechhold K, Patterson NB, Blum C, Fleischacker CL, Boehm BO, Harlan DM.

J Immunol. 2001 Feb 15;166(4):2531-9.PMID: 11160314 [PubMed - indexed for MEDLINE]Related articlesFree article

CD154 is a negative regulator of autoaggressive CD8+ T cells in type 1 diabetes.

McGregor CM, Schoenberger SP, Green EA.

Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9345-50. Epub 2004 Jun 10.PMID: 15192149 [PubMed - indexed for MEDLINE]Related articlesFree article

In situ characterization of dendritic cells occurring in the islets of nonobese diabetic mice during the development of insulitis.

Shinomiya M, Nadano S, Shinomiya H, Onji M.

Pancreas. 2000 Apr;20(3):290-6.PMID: 10766456 [PubMed - indexed for MEDLINE]Related articles

Amplification of autoimmune response through induction of dendritic cell maturation in inflamed tissues.

Melli K, Friedman RS, Martin AE, Finger EB, Miao G, Szot GL, Krummel MF, Tang Q.

J Immunol. 2009 Mar 1;182(5):2590-600.PMID: 19234153 [PubMed - indexed for MEDLINE]Related articles

Autoimmune diabetes in HLA-DR3/DQ8 transgenic mice expressing the co-stimulatory molecule B7-1 in the beta cells of islets of Langerhans.

Rajagopalan G, Kudva YC, Chen L, Wen L, David CS.

Int Immunol. 2003 Sep;15(9):1035-44.PMID: 12917255 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice.

Gagnerault MC, Luan JJ, Lotton C, Lepault F.

J Exp Med. 2002 Aug 5;196(3):369-77.PMID: 12163565 [PubMed - indexed for MEDLINE]Related articlesFree article

Transgenic mice expressing constitutive levels of IL-2 in islet beta cells develop diabetes.

Elliott EA, Flavell RA.

Int Immunol. 1994 Nov;6(11):1629-37.PMID: 7865456 [PubMed - indexed for MEDLINE]Related articles

Genetic differentiation of poly I:C from B:9-23 peptide induced experimental autoimmune diabetes.

Paronen J, Liu E, Moriyama H, Devendra D, Ide A, Taylor R, Yu L, Miao D, Melanitou E, Eisenbarth GS.

J Autoimmun. 2004 Jun;22(4):307-13.PMID: 15120754 [PubMed - indexed for MEDLINE]Related articles

Autoimmune insulitis and diabetes in the absence of antigen-specific contact between T cells and islet beta-cells.

Sarukhan A, Lechner O, von Boehmer H.

Eur J Immunol. 1999 Oct;29(10):3410-6.PMID: 10540353 [PubMed - indexed for MEDLINE]Related articles