PubMed

The phosphatidylserine receptor has essential functions during embryogenesis but not in apoptotic cell removal.

Böse J, Gruber AD, Helming L, Schiebe S, Wegener I, Hafner M, Beales M, Köntgen F, Lengeling A.

J Biol. 2004;3(4):15. Epub 2004 Aug 23.PMID: 15345036 [PubMed - indexed for MEDLINE]Related articlesFree article

Clearance of apoptotic cells is not impaired in mouse embryos deficient in class A scavenger receptor types I and II (CD204).

Komohara Y, Terasaki Y, Kaikita K, Suzuki H, Kodama T, Takeya M.

Dev Dyn. 2005 Jan;232(1):67-74.PMID: 15580571 [PubMed - indexed for MEDLINE]Related articlesFree article

Clearance of apoptotic photoreceptors: elimination of apoptotic debris into the subretinal space and macrophage-mediated phagocytosis via phosphatidylserine receptor and integrin alphavbeta3.

Hisatomi T, Sakamoto T, Sonoda KH, Tsutsumi C, Qiao H, Enaida H, Yamanaka I, Kubota T, Ishibashi T, Kura S, Susin SA, Kroemer G.

Am J Pathol. 2003 Jun;162(6):1869-79.PMID: 12759244 [PubMed - indexed for MEDLINE]Related articlesFree article

A receptor for phosphatidylserine-specific clearance of apoptotic cells.

Fadok VA, Bratton DL, Rose DM, Pearson A, Ezekewitz RA, Henson PM.

Nature. 2000 May 4;405(6782):85-90.PMID: 10811223 [PubMed - indexed for MEDLINE]Related articles

Transglutaminase type II is a key element in the regulation of the anti-inflammatory response elicited by apoptotic cell engulfment.

Falasca L, Iadevaia V, Ciccosanti F, Melino G, Serafino A, Piacentini M.

J Immunol. 2005 Jun 1;174(11):7330-40.PMID: 15905580 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphatidylserine receptor is required for clearance of apoptotic cells.

Li MO, Sarkisian MR, Mehal WZ, Rakic P, Flavell RA.

Science. 2003 Nov 28;302(5650):1560-3.PMID: 14645847 [PubMed - indexed for MEDLINE]Related articlesFree article

Defective fetal liver erythropoiesis and T lymphopoiesis in mice lacking the phosphatidylserine receptor.

Kunisaki Y, Masuko S, Noda M, Inayoshi A, Sanui T, Harada M, Sasazuki T, Fukui Y.

Blood. 2004 May 1;103(9):3362-4. Epub 2004 Jan 8.PMID: 14715629 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells.

Greenberg ME, Sun M, Zhang R, Febbraio M, Silverstein R, Hazen SL.

J Exp Med. 2006 Nov 27;203(12):2613-25. Epub 2006 Nov 13.PMID: 17101731 [PubMed - indexed for MEDLINE]Related articlesFree article

Elastase-mediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis.

Vandivier RW, Fadok VA, Hoffmann PR, Bratton DL, Penvari C, Brown KK, Brain JD, Accurso FJ, Henson PM.

J Clin Invest. 2002 Mar;109(5):661-70.PMID: 11877474 [PubMed - indexed for MEDLINE]Related articlesFree article

Phagocytosis of apoptotic cells and the resolution of inflammation.

Maderna P, Godson C.

Biochim Biophys Acta. 2003 Nov 20;1639(3):141-51. Review.PMID: 14636945 [PubMed - indexed for MEDLINE]Related articles

Apoptotic cells inhibit LPS-induced cytokine and chemokine production and IFN responses in macrophages.

Tassiulas I, Park-Min KH, Hu Y, Kellerman L, Mevorach D, Ivashkiv LB.

Hum Immunol. 2007 Mar;68(3):156-64. Epub 2007 Jan 8.PMID: 17349870 [PubMed - indexed for MEDLINE]Related articlesFree article

Surfactant proteins A and D suppress alveolar macrophage phagocytosis via interaction with SIRP alpha.

Janssen WJ, McPhillips KA, Dickinson MG, Linderman DJ, Morimoto K, Xiao YQ, Oldham KM, Vandivier RW, Henson PM, Gardai SJ.

Am J Respir Crit Care Med. 2008 Jul 15;178(2):158-67. Epub 2008 Apr 17.PMID: 18420961 [PubMed - indexed for MEDLINE]Related articlesFree article

Innate immune recognition of infected apoptotic cells directs T(H)17 cell differentiation.

Torchinsky MB, Garaude J, Martin AP, Blander JM.

Nature. 2009 Mar 5;458(7234):78-82.PMID: 19262671 [PubMed - indexed for MEDLINE]Related articles

Two alternative mechanisms that regulate the presentation of apoptotic cell engulfment signal in Caenorhabditis elegans.

Venegas V, Zhou Z.

Mol Biol Cell. 2007 Aug;18(8):3180-92. Epub 2007 Jun 13.PMID: 17567952 [PubMed - indexed for MEDLINE]Related articlesFree article

Programmed cell clearance.

Fadeel B.

Cell Mol Life Sci. 2003 Dec;60(12):2575-85. Review.PMID: 14685684 [PubMed - indexed for MEDLINE]Related articles

Loss of phospholipid asymmetry and surface exposure of phosphatidylserine is required for phagocytosis of apoptotic cells by macrophages and fibroblasts.

Fadok VA, de Cathelineau A, Daleke DL, Henson PM, Bratton DL.

J Biol Chem. 2001 Jan 12;276(2):1071-7.PMID: 10986279 [PubMed - indexed for MEDLINE]Related articlesFree article

If phosphatidylserine is the death knell, a new phosphatidylserine-specific receptor is the bellringer.

Fadok VA, Xue D, Henson P.

Cell Death Differ. 2001 Jun;8(6):582-7. Review.PMID: 11536008 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells.

Seitz HM, Camenisch TD, Lemke G, Earp HS, Matsushima GK.

J Immunol. 2007 May 1;178(9):5635-42.PMID: 17442946 [PubMed - indexed for MEDLINE]Related articlesFree article

Friendly fire against neutrophils: proteolytic enzymes confuse the recognition of apoptotic cells by macrophages.

Guzik K, Potempa J.

Biochimie. 2008 Feb;90(2):405-15. Epub 2007 Sep 22. Review.PMID: 17964056 [PubMed - indexed for MEDLINE]Related articles

The presumptive phosphatidylserine receptor is dispensable for innate anti-inflammatory recognition and clearance of apoptotic cells.

Mitchell JE, Cvetanovic M, Tibrewal N, Patel V, Colamonici OR, Li MO, Flavell RA, Levine JS, Birge RB, Ucker DS.

J Biol Chem. 2006 Mar 3;281(9):5718-25. Epub 2005 Nov 29.PMID: 16317002 [PubMed - indexed for MEDLINE]Related articlesFree article