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    Results: 1 to 20 of 119

    1.

    Regeneration of the heart in diabetes by selective copper chelation.

    Cooper GJ, Phillips AR, Choong SY, Leonard BL, Crossman DJ, Brunton DH, Saafi L, Dissanayake AM, Cowan BR, Young AA, Occleshaw CJ, Chan YK, Leahy FE, Keogh GF, Gamble GD, Allen GR, Pope AJ, Boyd PD, Poppitt SD, Borg TK, Doughty RN, Baker JR.

    Diabetes. 2004 Sep;53(9):2501-8.PMID: 15331567 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    A copper(II)-selective chelator ameliorates left-ventricular hypertrophy in type 2 diabetic patients: a randomised placebo-controlled study.

    Cooper GJ, Young AA, Gamble GD, Occleshaw CJ, Dissanayake AM, Cowan BR, Brunton DH, Baker JR, Phillips AR, Frampton CM, Poppitt SD, Doughty RN.

    Diabetologia. 2009 Apr;52(4):715-22. Epub 2009 Jan 27.PMID: 19172243 [PubMed - indexed for MEDLINE]Related articles

    3.

    Demonstration of a hyperglycemia-driven pathogenic abnormality of copper homeostasis in diabetes and its reversibility by selective chelation: quantitative comparisons between the biology of copper and eight other nutritionally essential elements in normal and diabetic individuals.

    Cooper GJ, Chan YK, Dissanayake AM, Leahy FE, Keogh GF, Frampton CM, Gamble GD, Brunton DH, Baker JR, Poppitt SD.

    Diabetes. 2005 May;54(5):1468-76.PMID: 15855335 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    A copper(II)-selective chelator ameliorates diabetes-evoked renal fibrosis and albuminuria, and suppresses pathogenic TGF-beta activation in the kidneys of rats used as a model of diabetes.

    Gong D, Lu J, Chen X, Reddy S, Crossman DJ, Glyn-Jones S, Choong YS, Kennedy J, Barry B, Zhang S, Chan YK, Ruggiero K, Phillips AR, Cooper GJ.

    Diabetologia. 2008 Sep;51(9):1741-51. Epub 2008 Jul 18.PMID: 18636238 [PubMed - indexed for MEDLINE]Related articles

    5.

    Molecular changes evoked by triethylenetetramine treatment in the extracellular matrix of the heart and aorta in diabetic rats.

    Gong D, Lu J, Chen X, Choong SY, Zhang S, Chan YK, Glyn-Jones S, Gamble GD, Phillips AR, Cooper GJ.

    Mol Pharmacol. 2006 Dec;70(6):2045-51. Epub 2006 Sep 14.PMID: 16973718 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Neurovascular dysfunction in diabetic rats. Potential contribution of autoxidation and free radicals examined using transition metal chelating agents.

    Cameron NE, Cotter MA.

    J Clin Invest. 1995 Aug;96(2):1159-63.PMID: 7635953 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    The metal chelators, trientine and citrate, inhibit the development of cardiac pathology in the Zucker diabetic rat.

    Baynes JW, Murray DB.

    Exp Diabetes Res. 2009;2009:696378. Epub 2009 Apr 15.PMID: 19390595 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Triethylenetetramine and metabolites: levels in relation to copper and zinc excretion in urine of healthy volunteers and type 2 diabetic patients.

    Lu J, Chan YK, Gamble GD, Poppitt SD, Othman AA, Cooper GJ.

    Drug Metab Dispos. 2007 Feb;35(2):221-7. Epub 2006 Nov 15.PMID: 17108057 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Gender related differential effects of Omega-3E treatment on diabetes-induced left ventricular dysfunction.

    Tuncay E, Seymen AA, Tanriverdi E, Yaras N, Tandogan B, Ulusu NN, Turan B.

    Mol Cell Biochem. 2007 Oct;304(1-2):255-63. Epub 2007 May 26.PMID: 17530185 [PubMed - indexed for MEDLINE]Related articles

    10.

    The mechanism of excretion of trientine from the rat kidney: trientine is not recognized by the H+/organic cation transporter.

    Kobayashi M, Tanabe R, Sugawara M, Iseki K, Miyazaki K.

    J Pharm Pharmacol. 1997 Apr;49(4):426-9.PMID: 9232542 [PubMed - indexed for MEDLINE]Related articles

    11.

    Anti-inflammatory effects of atorvastatin improve left ventricular function in experimental diabetic cardiomyopathy.

    Van Linthout S, Riad A, Dhayat N, Spillmann F, Du J, Dhayat S, Westermann D, Hilfiker-Kleiner D, Noutsias M, Laufs U, Schultheiss HP, Tschöpe C.

    Diabetologia. 2007 Sep;50(9):1977-86. Epub 2007 Jun 23.PMID: 17589825 [PubMed - indexed for MEDLINE]Related articles

    12.

    A copper chelating agent suppresses carbonyl stress in diabetic rat lenses.

    Hamada Y, Nakashima E, Naruse K, Nakae M, Naiki M, Fujisawa H, Oiso Y, Hotta N, Nakamura J.

    J Diabetes Complications. 2005 Nov-Dec;19(6):328-34.PMID: 16260349 [PubMed - indexed for MEDLINE]Related articles

    13.

    Altered expression of gap junction connexin proteins may partly underlie heart rhythm disturbances in the streptozotocin-induced diabetic rat heart.

    Howarth FC, Nowotny N, Zilahi E, El Haj MA, Lei M.

    Mol Cell Biochem. 2007 Nov;305(1-2):145-51. Epub 2007 Jul 14.PMID: 17632690 [PubMed - indexed for MEDLINE]Related articles

    14.

    Role of Ca2+/calmodulin-dependent protein kinase II in development of vascular dysfunction in diabetic rats with hypertension.

    Yousif MH, Akhtar S, Walther T, Benter IF.

    Cell Biochem Funct. 2008 Mar-Apr;26(2):256-63.PMID: 18035860 [PubMed - indexed for MEDLINE]Related articles

    15.

    Effect of telmisartan on cardiovascular complications associated with streptozotocin diabetic rats.

    Goyal BR, Mesariya P, Goyal RK, Mehta AA.

    Mol Cell Biochem. 2008 Jul;314(1-2):123-31. Epub 2008 Apr 19.PMID: 18425420 [PubMed - indexed for MEDLINE]Related articles

    16.

    Effects of a selective bradykinin B1 receptor antagonist on increased plasma extravasation in streptozotocin-induced diabetic rats: distinct vasculopathic profile of major key organs.

    Lawson SR, Gabra BH, Nantel F, Battistini B, Sirois P.

    Eur J Pharmacol. 2005 May 2;514(1):69-78. Epub 2005 Apr 21.PMID: 15878326 [PubMed - indexed for MEDLINE]Related articles

    17.

    Toxicity of copper intake: lipid profile, oxidative stress and susceptibility to renal dysfunction.

    Galhardi CM, Diniz YS, Faine LA, Rodrigues HG, Burneiko RC, Ribas BO, Novelli EL.

    Food Chem Toxicol. 2004 Dec;42(12):2053-60.PMID: 15500942 [PubMed - indexed for MEDLINE]Related articles

    18.

    Inflammation induced by photocoagulation laser is minimized by copper chelators.

    Cui JZ, Wang XF, Hsu L, Matsubara JA.

    Lasers Med Sci. 2009 Jul;24(4):653-7. Epub 2008 Jun 20.PMID: 18566852 [PubMed - indexed for MEDLINE]Related articles

    19.

    Insulin treatment decreases the antioxidant defense mechanism in experimental diabetes.

    Somogyi A, Ruzicska E, Blázovics A, Vér A, Rosta K, Tóth M.

    Med Sci Monit. 2005 Jul;11(7):BR206-11. Epub 2005 Jun 29.PMID: 15990681 [PubMed - indexed for MEDLINE]Related articles

    20.

    Trientine, a copper-chelating agent, induced apoptosis in murine fibrosarcoma cells in vivo and in vitro.

    Hayashi M, Nishiya H, Chiba T, Endoh D, Kon Y, Okui T.

    J Vet Med Sci. 2007 Feb;69(2):137-42.PMID: 17339757 [PubMed - indexed for MEDLINE]Related articlesFree article

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