PubMed

Increased expression of Gi-coupled muscarinic acetylcholine receptor and Gi in atrium of elderly diabetic subjects.

Richardson MD, Kilts JD, Kwatra MM.

Diabetes. 2004 Sep;53(9):2392-6.PMID: 15331550 [PubMed - indexed for MEDLINE]Related articlesFree article

Age increases cardiac Galpha(i2) expression, resulting in enhanced coupling to G protein-coupled receptors.

Kilts JD, Akazawa T, Richardson MD, Kwatra MM.

J Biol Chem. 2002 Aug 23;277(34):31257-62. Epub 2002 Jun 13.PMID: 12065589 [PubMed - indexed for MEDLINE]Related articlesFree article

Galpha(i2) but not Galpha(i3) is required for muscarinic inhibition of contractility and calcium currents in adult cardiomyocytes.

Nagata K, Ye C, Jain M, Milstone DS, Liao R, Mortensen RM.

Circ Res. 2000 Nov 10;87(10):903-9.PMID: 11073886 [PubMed - indexed for MEDLINE]Related articlesFree article

Galphai1 and Galphai3 differentially interact with, and regulate, the G protein-activated K+ channel.

Ivanina T, Varon D, Peleg S, Rishal I, Porozov Y, Dessauer CW, Keren-Raifman T, Dascal N.

J Biol Chem. 2004 Apr 23;279(17):17260-8. Epub 2004 Feb 12.PMID: 14963032 [PubMed - indexed for MEDLINE]Related articlesFree article

Age increases expression and receptor-mediated activation of G alpha i in human atria.

Kilts JD, Akazawa T, El-Moalem HE, Mathew JP, Newman MF, Kwatra MM.

J Cardiovasc Pharmacol. 2003 Nov;42(5):662-70.PMID: 14576516 [PubMed - indexed for MEDLINE]Related articles

TGFbeta regulates the expression of G alpha(i2) via an effect on the localization of ras.

Ward SM, Gadbut AP, Tang D, Papageorge AG, Wu L, Li G, Barnett JV, Galper JB.

J Mol Cell Cardiol. 2002 Sep;34(9):1217-26.PMID: 12392895 [PubMed - indexed for MEDLINE]Related articles

Lack of muscarinic regulation of Ca(2+) channels in G(i2)alpha gene knockout mouse hearts.

Chen F, Spicher K, Jiang M, Birnbaumer L, Wetzel GT.

Am J Physiol Heart Circ Physiol. 2001 May;280(5):H1989-95.PMID: 11299198 [PubMed - indexed for MEDLINE]Related articlesFree article

Specificity of Gbetagamma signaling to Kir3 channels depends on the helical domain of pertussis toxin-sensitive Galpha subunits.

Rusinova R, Mirshahi T, Logothetis DE.

J Biol Chem. 2007 Nov 23;282(47):34019-30. Epub 2007 Sep 14.PMID: 17872944 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of G-protein-specific antibodies and G beta gamma subunits on the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells.

Yan HD, Okamoto H, Unno T, Tsytsyura YD, Prestwich SA, Komori S, Zholos AV, Bolton TB.

Br J Pharmacol. 2003 Jun;139(3):605-15.PMID: 12788820 [PubMed - indexed for MEDLINE]Related articlesFree article

mRNA and protein expression of selective alpha subunits of G proteins are abnormal in prefrontal cortex of suicide victims.

Dwivedi Y, Rizavi HS, Conley RR, Roberts RC, Tamminga CA, Pandey GN.

Neuropsychopharmacology. 2002 Oct;27(4):499-517.PMID: 12377388 [PubMed - indexed for MEDLINE]Related articlesFree article

RGS6, RGS7, RGS9, and RGS11 stimulate GTPase activity of Gi family G-proteins with differential selectivity and maximal activity.

Hooks SB, Waldo GL, Corbitt J, Bodor ET, Krumins AM, Harden TK.

J Biol Chem. 2003 Mar 21;278(12):10087-93. Epub 2003 Jan 16.PMID: 12531899 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional coupling of the human dopamine D2 receptor with G alpha i1, G alpha i2, G alpha i3 and G alpha o G proteins: evidence for agonist regulation of G protein selectivity.

Gazi L, Nickolls SA, Strange PG.

Br J Pharmacol. 2003 Mar;138(5):775-86.PMID: 12642378 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipid lowering by pravastatin increases parasympathetic modulation of heart rate: Galpha(i2), a possible molecular marker for parasympathetic responsiveness.

Welzig CM, Shin DG, Park HJ, Kim YJ, Saul JP, Galper JB.

Circulation. 2003 Dec 2;108(22):2743-6. Epub 2003 Nov 17.PMID: 14623802 [PubMed - indexed for MEDLINE]Related articlesFree article

Acetylcholine release in human heart atrium: influence of muscarinic autoreceptors, diabetes, and age.

Oberhauser V, Schwertfeger E, Rutz T, Beyersdorf F, Rump LC.

Circulation. 2001 Mar 27;103(12):1638-43.PMID: 11273990 [PubMed - indexed for MEDLINE]Related articlesFree article

Opposing changes of trimeric G protein levels during ontogenetic development of rat brain.

Ihnatovych I, Novotny J, Haugvicova R, Bourova L, Mares P, Svoboda P.

Brain Res Dev Brain Res. 2002 Jan 31;133(1):57-67.PMID: 11850064 [PubMed - indexed for MEDLINE]Related articles

Cardioprotection specific for the G protein Gi2 in chronic adrenergic signaling through beta 2-adrenoceptors.

Foerster K, Groner F, Matthes J, Koch WJ, Birnbaumer L, Herzig S.

Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14475-80. Epub 2003 Nov 11.PMID: 14612574 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential coupling of m-cholinoceptors to Gi/Go-proteins in failing human myocardium.

Mittmann C, Pinkepank G, Stamatelopoulou S, Wieland T, Nürnberg B, Hirt S, Eschenhagen T.

J Mol Cell Cardiol. 2003 Oct;35(10):1241-9.PMID: 14519434 [PubMed - indexed for MEDLINE]Related articles

Tissue-specific regulation of GTP-binding protein and muscarinic acetylcholine receptor levels during cardiac development.

Luetje CW, Gierschik P, Milligan G, Unson C, Spiegel A, Nathanson NM.

Biochemistry. 1987 Jul 28;26(15):4876-84.PMID: 3117107 [PubMed - indexed for MEDLINE]Related articles

Heterooligomers of the muscarinic receptor and G proteins purified from porcine atria.

Ma AW, Pawagi AB, Wells JW.

Biochem Biophys Res Commun. 2008 Sep 12;374(1):128-33. Epub 2008 Jul 2.PMID: 18601900 [PubMed - indexed for MEDLINE]Related articles

Protean agonism at the dopamine D2 receptor: (S)-3-(3-hydroxyphenyl)-N-propylpiperidine is an agonist for activation of Go1 but an antagonist/inverse agonist for Gi1,Gi2, and Gi3.

Lane JR, Powney B, Wise A, Rees S, Milligan G.

Mol Pharmacol. 2007 May;71(5):1349-59. Epub 2007 Feb 7.PMID: 17287401 [PubMed - indexed for MEDLINE]Related articlesFree article