PubMed

Syntaxin 4 transgenic mice exhibit enhanced insulin-mediated glucose uptake in skeletal muscle.

Spurlin BA, Park SY, Nevins AK, Kim JK, Thurmond DC.

Diabetes. 2004 Sep;53(9):2223-31.PMID: 15331531 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance in tetracycline-repressible Munc18c transgenic mice.

Spurlin BA, Thomas RM, Nevins AK, Kim HJ, Kim YJ, Noh HL, Shulman GI, Kim JK, Thurmond DC.

Diabetes. 2003 Aug;52(8):1910-7.PMID: 12882905 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipocytes from Munc18c-null mice show increased sensitivity to insulin-stimulated GLUT4 externalization.

Kanda H, Tamori Y, Shinoda H, Yoshikawa M, Sakaue M, Udagawa J, Otani H, Tashiro F, Miyazaki J, Kasuga M.

J Clin Invest. 2005 Feb;115(2):291-301.PMID: 15690082 [PubMed - indexed for MEDLINE]Related articlesFree article

Munc18c regulates insulin-stimulated glut4 translocation to the transverse tubules in skeletal muscle.

Khan AH, Thurmond DC, Yang C, Ceresa BP, Sigmund CD, Pessin JE.

J Biol Chem. 2001 Feb 9;276(6):4063-9. Epub 2000 Oct 27.PMID: 11054418 [PubMed - indexed for MEDLINE]Related articlesFree article

Munc18c heterozygous knockout mice display increased susceptibility for severe glucose intolerance.

Oh E, Spurlin BA, Pessin JE, Thurmond DC.

Diabetes. 2005 Mar;54(3):638-47.PMID: 15734838 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular munc18c levels can modulate glucose transport rate and GLUT4 translocation in 3T3L1 cells.

Macaulay SL, Grusovin J, Stoichevska V, Ryan JM, Castelli LA, Ward CW.

FEBS Lett. 2002 Sep 25;528(1-3):154-60.PMID: 12297296 [PubMed - indexed for MEDLINE]Related articles

Regulation of insulin-stimulated GLUT4 translocation by Munc18c in 3T3L1 adipocytes.

Thurmond DC, Ceresa BP, Okada S, Elmendorf JS, Coker K, Pessin JE.

J Biol Chem. 1998 Dec 11;273(50):33876-83.PMID: 9837979 [PubMed - indexed for MEDLINE]Related articlesFree article

Syntaxin 4 heterozygous knockout mice develop muscle insulin resistance.

Yang C, Coker KJ, Kim JK, Mora S, Thurmond DC, Davis AC, Yang B, Williamson RA, Shulman GI, Pessin JE.

J Clin Invest. 2001 May;107(10):1311-8.PMID: 11375421 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantification of SNARE protein levels in 3T3-L1 adipocytes: implications for insulin-stimulated glucose transport.

Hickson GR, Chamberlain LH, Maier VH, Gould GW.

Biochem Biophys Res Commun. 2000 Apr 21;270(3):841-5.PMID: 10772913 [PubMed - indexed for MEDLINE]Related articles

Inhibition of insulin-induced GLUT4 translocation by Munc18c through interaction with syntaxin4 in 3T3-L1 adipocytes.

Tamori Y, Kawanishi M, Niki T, Shinoda H, Araki S, Okazawa H, Kasuga M.

J Biol Chem. 1998 Jul 31;273(31):19740-6.PMID: 9677404 [PubMed - indexed for MEDLINE]Related articlesFree article

Discrimination of GLUT4 vesicle trafficking from fusion using a temperature-sensitive Munc18c mutant.

Thurmond DC, Pessin JE.

EMBO J. 2000 Jul 17;19(14):3565-75.PMID: 10899111 [PubMed - indexed for MEDLINE]Related articlesFree article

The synaptic vesicle protein, cysteine-string protein, is associated with the plasma membrane in 3T3-L1 adipocytes and interacts with syntaxin 4.

Chamberlain LH, Graham ME, Kane S, Jackson JL, Maier VH, Burgoyne RD, Gould GW.

J Cell Sci. 2001 Jan;114(Pt 2):445-55.PMID: 11148145 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin-stimulated translocation of GLUT4 glucose transporters requires SNARE-complex proteins.

Cheatham B, Volchuk A, Kahn CR, Wang L, Rhodes CJ, Klip A.

Proc Natl Acad Sci U S A. 1996 Dec 24;93(26):15169-73.PMID: 8986782 [PubMed - indexed for MEDLINE]Related articlesFree article

Munc18c function is required for insulin-stimulated plasma membrane fusion of GLUT4 and insulin-responsive amino peptidase storage vesicles.

Thurmond DC, Kanzaki M, Khan AH, Pessin JE.

Mol Cell Biol. 2000 Jan;20(1):379-88.PMID: 10594040 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of protein kinase C zeta induces serine phosphorylation of VAMP2 in the GLUT4 compartment and increases glucose transport in skeletal muscle.

Braiman L, Alt A, Kuroki T, Ohba M, Bak A, Tennenbaum T, Sampson SR.

Mol Cell Biol. 2001 Nov;21(22):7852-61.PMID: 11604519 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose-specific overexpression of GLUT4 reverses insulin resistance and diabetes in mice lacking GLUT4 selectively in muscle.

Carvalho E, Kotani K, Peroni OD, Kahn BB.

Am J Physiol Endocrinol Metab. 2005 Oct;289(4):E551-61. Epub 2005 May 31.PMID: 15928024 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of SNARE's in the GLUT4 translocation response to insulin in adipose cells and muscle.

St-Denis JF, Cushman SW.

J Basic Clin Physiol Pharmacol. 1998;9(2-4):153-65. Review.PMID: 10212832 [PubMed - indexed for MEDLINE]Related articles

Insulin-responsive tissues contain the core complex protein SNAP-25 (synaptosomal-associated protein 25) A and B isoforms in addition to syntaxin 4 and synaptobrevins 1 and 2.

Jagadish MN, Fernandez CS, Hewish DR, Macaulay SL, Gough KH, Grusovin J, Verkuylen A, Cosgrove L, Alafaci A, Frenkel MJ, Ward CW.

Biochem J. 1996 Aug 1;317 ( Pt 3):945-54.PMID: 8760387 [PubMed - indexed for MEDLINE]Related articlesFree article

Lilly lecture 1995. Glucose transport: pivotal step in insulin action.

Kahn BB.

Diabetes. 1996 Nov;45(11):1644-54. Review.PMID: 8866574 [PubMed - indexed for MEDLINE]Related articles

Increased expression of the SNARE accessory protein Munc18c in lipid-mediated insulin resistance.

Schlaepfer IR, Pulawa LK, Ferreira LD, James DE, Capell WH, Eckel RH.

J Lipid Res. 2003 Jun;44(6):1174-81. Epub 2003 Apr 16.PMID: 12700337 [PubMed - indexed for MEDLINE]Related articlesFree article