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    Results: 1 to 20 of 283

    1.

    Diminished loss of proteoglycans and lack of albuminuria in protein kinase C-alpha-deficient diabetic mice.

    Menne J, Park JK, Boehne M, Elger M, Lindschau C, Kirsch T, Meier M, Gueler F, Fiebeler A, Bahlmann FH, Leitges M, Haller H.

    Diabetes. 2004 Aug;53(8):2101-9.PMID: 15277392 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Deletion of protein kinase C-beta isoform in vivo reduces renal hypertrophy but not albuminuria in the streptozotocin-induced diabetic mouse model.

    Meier M, Park JK, Overheu D, Kirsch T, Lindschau C, Gueler F, Leitges M, Menne J, Haller H.

    Diabetes. 2007 Feb;56(2):346-54.PMID: 17259378 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase Cbeta-null mice.

    Ohshiro Y, Ma RC, Yasuda Y, Hiraoka-Yamamoto J, Clermont AC, Isshiki K, Yagi K, Arikawa E, Kern TS, King GL.

    Diabetes. 2006 Nov;55(11):3112-20.PMID: 17065350 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Antiangiogenic endostatin peptide ameliorates renal alterations in the early stage of a type 1 diabetic nephropathy model.

    Ichinose K, Maeshima Y, Yamamoto Y, Kitayama H, Takazawa Y, Hirokoshi K, Sugiyama H, Yamasaki Y, Eguchi K, Makino H.

    Diabetes. 2005 Oct;54(10):2891-903. Erratum in: Diabetes. 2006 Sep;55(9):2665. PMID: 16186390 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    p27(Kip1) Knockout mice are protected from diabetic nephropathy: evidence for p27(Kip1) haplotype insufficiency.

    Wolf G, Schanze A, Stahl RA, Shankland SJ, Amann K.

    Kidney Int. 2005 Oct;68(4):1583-9.PMID: 16164635 [PubMed - indexed for MEDLINE]Related articles

    6.

    Glucose-induced TGF-beta1 and TGF-beta receptor-1 expression in vascular smooth muscle cells is mediated by protein kinase C-alpha.

    Lindschau C, Quass P, Menne J, Güler F, Fiebeler A, Leitges M, Luft FC, Haller H.

    Hypertension. 2003 Sep;42(3):335-41. Epub 2003 Aug 25.PMID: 12939231 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes.

    Koya D, Haneda M, Nakagawa H, Isshiki K, Sato H, Maeda S, Sugimoto T, Yasuda H, Kashiwagi A, Ways DK, King GL, Kikkawa R.

    FASEB J. 2000 Mar;14(3):439-47.PMID: 10698958 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Protein kinase C beta inhibition attenuates the progression of experimental diabetic nephropathy in the presence of continued hypertension.

    Kelly DJ, Zhang Y, Hepper C, Gow RM, Jaworski K, Kemp BE, Wilkinson-Berka JL, Gilbert RE.

    Diabetes. 2003 Feb;52(2):512-8.PMID: 12540629 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Nephrin loss in experimental diabetic nephropathy is prevented by deletion of protein kinase C alpha signaling in-vivo.

    Menne J, Meier M, Park JK, Boehne M, Kirsch T, Lindschau C, Ociepka R, Leitges M, Rinta-Valkama J, Holthofer H, Haller H.

    Kidney Int. 2006 Oct;70(8):1456-62. Epub 2006 Sep 6.PMID: 16955103 [PubMed - indexed for MEDLINE]Related articles

    10.

    Effect of telmisartan on expression of protein kinase C-alpha in kidneys of diabetic mice.

    Yao LJ, Wang JQ, Zhao H, Liu JS, Deng AG.

    Acta Pharmacol Sin. 2007 Jun;28(6):829-38.PMID: 17506942 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    [Protein kinase C-betaI, betaII in mouse diabetic nephropathy kidney and its relation to nephroprotective actions of the angiotensin receptor blocker telmisartan]

    Yao LJ, Wang JQ, Deng AG, Liu JS.

    Zhonghua Yi Xue Za Zhi. 2007 Jul 24;87(28):1991-5. Chinese. PMID: 17923043 [PubMed - indexed for MEDLINE]Related articles

    12.

    Effects on protein kinase C-beta inhibition on glomerular vascular endothelial growth factor expression and endothelial cells in advanced experimental diabetic nephropathy.

    Kelly DJ, Buck D, Cox AJ, Zhang Y, Gilbert RE.

    Am J Physiol Renal Physiol. 2007 Aug;293(2):F565-74. Epub 2007 May 23.PMID: 17522264 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    The cyclin kinase inhibitor p21WAF1/CIP1 is required for glomerular hypertrophy in experimental diabetic nephropathy.

    Al-Douahji M, Brugarolas J, Brown PA, Stehman-Breen CO, Alpers CE, Shankland SJ.

    Kidney Int. 1999 Nov;56(5):1691-9.PMID: 10571777 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Evaluation of renal gene expression of protein kinase C (PKC) isoforms in diabetic and nondiabetic proliferative glomerular diseases.

    Ibrahim S, Rashed L, Fadda S.

    ScientificWorldJournal. 2008 Aug 31;8:835-44.PMID: 18758661 [PubMed - indexed for MEDLINE]Related articles

    15.

    Evidence linking glycated albumin to altered glomerular nephrin and VEGF expression, proteinuria, and diabetic nephropathy.

    Cohen MP, Chen S, Ziyadeh FN, Shea E, Hud EA, Lautenslager GT, Shearman CW.

    Kidney Int. 2005 Oct;68(4):1554-61.PMID: 16164632 [PubMed - indexed for MEDLINE]Related articles

    16.

    Increased renal gene transcription of protein kinase C-beta in human diabetic nephropathy: relationship to long-term glycaemic control.

    Langham RG, Kelly DJ, Gow RM, Zhang Y, Cox AJ, Qi W, Thai K, Pollock CA, Christensen PK, Parving HH, Gilbert RE.

    Diabetologia. 2008 Apr;51(4):668-74. Epub 2008 Feb 16.PMID: 18278479 [PubMed - indexed for MEDLINE]Related articles

    17.

    Attenuation of extracellular matrix accumulation in diabetic nephropathy by the advanced glycation end product cross-link breaker ALT-711 via a protein kinase C-alpha-dependent pathway.

    Thallas-Bonke V, Lindschau C, Rizkalla B, Bach LA, Boner G, Meier M, Haller H, Cooper ME, Forbes JM.

    Diabetes. 2004 Nov;53(11):2921-30.PMID: 15504973 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Interference with TGF-beta signaling by Smad3-knockout in mice limits diabetic glomerulosclerosis without affecting albuminuria.

    Wang A, Ziyadeh FN, Lee EY, Pyagay PE, Sung SH, Sheardown SA, Laping NJ, Chen S.

    Am J Physiol Renal Physiol. 2007 Nov;293(5):F1657-65. Epub 2007 Sep 5.PMID: 17804483 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Pathogenesis of the podocytopathy and proteinuria in diabetic glomerulopathy.

    Ziyadeh FN, Wolf G.

    Curr Diabetes Rev. 2008 Feb;4(1):39-45. Review.PMID: 18220694 [PubMed - indexed for MEDLINE]Related articles

    20.

    Amelioration of long-term renal changes in obese type 2 diabetic mice by a neutralizing vascular endothelial growth factor antibody.

    Flyvbjerg A, Dagnaes-Hansen F, De Vriese AS, Schrijvers BF, Tilton RG, Rasch R.

    Diabetes. 2002 Oct;51(10):3090-4.PMID: 12351452 [PubMed - indexed for MEDLINE]Related articlesFree article

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