PubMed

Splanchnic cortisol production occurs in humans: evidence for conversion of cortisone to cortisol via the 11-beta hydroxysteroid dehydrogenase (11beta-hsd) type 1 pathway.

Basu R, Singh RJ, Basu A, Chittilapilly EG, Johnson CM, Toffolo G, Cobelli C, Rizza RA.

Diabetes. 2004 Aug;53(8):2051-9.PMID: 15277385 [PubMed - indexed for MEDLINE]Related articlesFree article

Obesity and type 2 diabetes do not alter splanchnic cortisol production in humans.

Basu R, Singh RJ, Basu A, Chittilapilly EG, Johnson MC, Toffolo G, Cobelli C, Rizza RA.

J Clin Endocrinol Metab. 2005 Jul;90(7):3919-26. Epub 2005 Apr 5.PMID: 15811928 [PubMed - indexed for MEDLINE]Related articlesFree article

Splanchnic cortisol production in dogs occurs primarily in the liver: evidence for substantial hepatic specific 11beta hydroxysteroid dehydrogenase type 1 activity.

Basu R, Edgerton DS, Singh RJ, Cherrington A, Rizza RA.

Diabetes. 2006 Nov;55(11):3013-9.PMID: 17065337 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of nutrient ingestion on total-body and splanchnic cortisol production in humans.

Basu R, Singh R, Basu A, Johnson CM, Rizza RA.

Diabetes. 2006 Mar;55(3):667-74.PMID: 16505229 [PubMed - indexed for MEDLINE]Related articlesFree article

Liver is the site of splanchnic cortisol production in obese nondiabetic humans.

Basu R, Basu A, Grudzien M, Jung P, Jacobson P, Johnson M, Singh R, Sarr M, Rizza RA.

Diabetes. 2009 Jan;58(1):39-45. Epub 2008 Oct 13. Erratum in: Diabetes. 2009 Aug;58(8):1936. PMID: 18852327 [PubMed - indexed for MEDLINE]Related articlesFree article

Growth hormone, insulin-like growth factor-I and the cortisol-cortisone shuttle.

Stewart PM, Toogood AA, Tomlinson JW.

Horm Res. 2001;56 Suppl 1:1-6. Review.PMID: 11786677 [PubMed - indexed for MEDLINE]Related articles

The contribution of visceral adipose tissue to splanchnic cortisol production in healthy humans.

Andrew R, Westerbacka J, Wahren J, Yki-Järvinen H, Walker BR.

Diabetes. 2005 May;54(5):1364-70.PMID: 15855321 [PubMed - indexed for MEDLINE]Related articlesFree article

Body fat distribution and cortisol metabolism in healthy men: enhanced 5beta-reductase and lower cortisol/cortisone metabolite ratios in men with fatty liver.

Westerbacka J, Yki-Järvinen H, Vehkavaara S, Häkkinen AM, Andrew R, Wake DJ, Seckl JR, Walker BR.

J Clin Endocrinol Metab. 2003 Oct;88(10):4924-31.PMID: 14557475 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo activity of 11beta-hydroxysteroid dehydrogenase type 1 and free fatty acid-induced insulin resistance.

Mai K, Kullmann V, Bobbert T, Maser-Gluth C, Möhlig M, Bähr V, Pfeiffer AF, Spranger J, Diederich S.

Clin Endocrinol (Oxf). 2005 Oct;63(4):442-9.PMID: 16181237 [PubMed - indexed for MEDLINE]Related articles

Insulin dose-response curves for stimulation of splanchnic glucose uptake and suppression of endogenous glucose production differ in nondiabetic humans and are abnormal in people with type 2 diabetes.

Basu R, Basu A, Johnson CM, Schwenk WF, Rizza RA.

Diabetes. 2004 Aug;53(8):2042-50.PMID: 15277384 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue-specific changes in peripheral cortisol metabolism in obese women: increased adipose 11beta-hydroxysteroid dehydrogenase type 1 activity.

Rask E, Walker BR, Söderberg S, Livingstone DE, Eliasson M, Johnson O, Andrew R, Olsson T.

J Clin Endocrinol Metab. 2002 Jul;87(7):3330-6.PMID: 12107245 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of relationship between 11beta-hydroxysteroid dehydrogenase setpoint and insulin sensitivity in the basal state and after 24h of insulin infusion in healthy subjects and type 2 diabetic patients.

Kerstens MN, Riemens SC, Sluiter WJ, Pratt JJ, Wolthers BG, Dullaart RP.

Clin Endocrinol (Oxf). 2000 Apr;52(4):403-11.PMID: 10762282 [PubMed - indexed for MEDLINE]Related articles

Short-term cortisol infusion in the brachial artery, with and without inhibiting 11 beta-hydroxysteroid dehydrogenase, does not alter forearm vascular resistance in normotensive and hypertensive subjects.

van Uum SH, Hermus AR, Sweep CG, Walker BR, Ross HA, de Leeuw PW, Lenders JW.

Eur J Clin Invest. 2002 Dec;32(12):874-81.PMID: 12534445 [PubMed - indexed for MEDLINE]Related articles

Abnormal cortisol metabolism and tissue sensitivity to cortisol in patients with glucose intolerance.

Andrews RC, Herlihy O, Livingstone DE, Andrew R, Walker BR.

J Clin Endocrinol Metab. 2002 Dec;87(12):5587-93.PMID: 12466357 [PubMed - indexed for MEDLINE]Related articlesFree article

Assessing systemic 11beta-hydroxysteroid dehydrogenase with serum cortisone/cortisol ratios in healthy subjects and patients with diabetes mellitus and chronic renal failure.

Homma M, Tanaka A, Hino K, Takamura H, Hirano T, Oka K, Kanazawa M, Miwa T, Notoya Y, Niitsuma T, Hayashi T.

Metabolism. 2001 Jul;50(7):801-4.PMID: 11436185 [PubMed - indexed for MEDLINE]Related articles

Effects of free fatty acids and glycerol on splanchnic glucose metabolism and insulin extraction in nondiabetic humans.

Shah P, Vella A, Basu A, Basu R, Adkins A, Schwenk WF, Johnson CM, Nair KS, Jensen MD, Rizza RA.

Diabetes. 2002 Feb;51(2):301-10.PMID: 11812736 [PubMed - indexed for MEDLINE]Related articlesFree article

Splanchnic and leg substrate exchange after ingestion of a natural mixed meal in humans.

Capaldo B, Gastaldelli A, Antoniello S, Auletta M, Pardo F, Ciociaro D, Guida R, Ferrannini E, Saccà L.

Diabetes. 1999 May;48(5):958-66.PMID: 10331398 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute intrarenal administration of cortisol has no effect on renal blood flow in hypertensive individuals.

van Uum SH, Houben AJ, Hermus AR, Kroon AA, Walker BR, Sweep CG, Smits P, de Leeuw PW, Lenders JW.

J Hypertens. 2002 Nov;20(11):2275-83.PMID: 12409967 [PubMed - indexed for MEDLINE]Related articles

Acute in vivo regulation of 11beta-hydroxysteroid dehydrogenase type 1 activity by insulin and intralipid infusions in humans.

Wake DJ, Homer NZ, Andrew R, Walker BR.

J Clin Endocrinol Metab. 2006 Nov;91(11):4682-8. Epub 2006 Sep 5.PMID: 16954164 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of 11beta-hydroxysteroid dehydrogenase-1 in adipose tissue is associated with acquired obesity and features of insulin resistance: studies in young adult monozygotic twins.

Kannisto K, Pietiläinen KH, Ehrenborg E, Rissanen A, Kaprio J, Hamsten A, Yki-Järvinen H.

J Clin Endocrinol Metab. 2004 Sep;89(9):4414-21.PMID: 15356040 [PubMed - indexed for MEDLINE]Related articlesFree article