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Insulin dose-response curves for stimulation of splanchnic glucose uptake and suppression of endogenous glucose production differ in nondiabetic humans and are abnormal in people with type 2 diabetes.
Basu R, Basu A, Johnson CM, Schwenk WF, Rizza RA.
Diabetes. 2004 Aug;53(8):2042-50.PMID: 15277384 [PubMed - indexed for MEDLINE]Related articlesFree article
Effects of type 2 diabetes on the ability of insulin and glucose to regulate splanchnic and muscle glucose metabolism: evidence for a defect in hepatic glucokinase activity.
Basu A, Basu R, Shah P, Vella A, Johnson CM, Nair KS, Jensen MD, Schwenk WF, Rizza RA.
Diabetes. 2000 Feb;49(2):272-83.PMID: 10868944 [PubMed - indexed for MEDLINE]Related articlesFree article
Normal glucose-induced suppression of glucose production but impaired stimulation of glucose disposal in type 2 diabetes: evidence for a concentration-dependent defect in uptake.
Nielsen MF, Basu R, Wise S, Caumo A, Cobelli C, Rizza RA.
Diabetes. 1998 Nov;47(11):1735-47.PMID: 9792543 [PubMed - indexed for MEDLINE]Related articlesFree article
Pioglitazone reduces hepatic fat content and augments splanchnic glucose uptake in patients with type 2 diabetes.
Bajaj M, Suraamornkul S, Pratipanawatr T, Hardies LJ, Pratipanawatr W, Glass L, Cersosimo E, Miyazaki Y, DeFronzo RA.
Diabetes. 2003 Jun;52(6):1364-70.PMID: 12765945 [PubMed - indexed for MEDLINE]Related articlesFree article
Impaired basal glucose effectiveness in NIDDM: contribution of defects in glucose disappearance and production, measured using an optimized minimal model independent protocol.
Basu A, Caumo A, Bettini F, Gelisio A, Alzaid A, Cobelli C, Rizza RA.
Diabetes. 1997 Mar;46(3):421-32.PMID: 9032098 [PubMed - indexed for MEDLINE]Related articles
Evidence for decreased splanchnic glucose uptake after oral glucose administration in non-insulin-dependent diabetes mellitus.
Ludvik B, Nolan JJ, Roberts A, Baloga J, Joyce M, Bell JM, Olefsky JM.
J Clin Invest. 1997 Nov 1;100(9):2354-61.PMID: 9410915 [PubMed - indexed for MEDLINE]Related articlesFree article
Type 2 diabetes impairs splanchnic uptake of glucose but does not alter intestinal glucose absorption during enteral glucose feeding: additional evidence for a defect in hepatic glucokinase activity.
Basu A, Basu R, Shah P, Vella A, Johnson CM, Jensen M, Nair KS, Schwenk WF, Rizza RA.
Diabetes. 2001 Jun;50(6):1351-62.PMID: 11375336 [PubMed - indexed for MEDLINE]Related articlesFree article
Regulation of endogenous glucose production by glucose per se is impaired in type 2 diabetes mellitus.
Mevorach M, Giacca A, Aharon Y, Hawkins M, Shamoon H, Rossetti L.
J Clin Invest. 1998 Aug 15;102(4):744-53.PMID: 9710443 [PubMed - indexed for MEDLINE]Related articlesFree article
Free fatty acids reduce splanchnic and peripheral glucose uptake in patients with type 2 diabetes.
Bajaj M, Pratipanawatr T, Berria R, Pratipanawatr W, Kashyap S, Cusi K, Mandarino L, DeFronzo RA.
Diabetes. 2002 Oct;51(10):3043-8.PMID: 12351445 [PubMed - indexed for MEDLINE]Related articlesFree article
Effect of glucagon-like peptide-1(7-36)-amide on initial splanchnic glucose uptake and insulin action in humans with type 1 diabetes.
Vella A, Shah P, Basu R, Basu A, Camilleri M, Schwenk FW, Holst JJ, Rizza RA.
Diabetes. 2001 Mar;50(3):565-72.PMID: 11246876 [PubMed - indexed for MEDLINE]Related articlesFree article
Assessment of insulin action in NIDDM in the presence of dynamic changes in insulin and glucose concentration.
Katz H, Homan M, Jensen M, Caumo A, Cobelli C, Rizza R.
Diabetes. 1994 Feb;43(2):289-96.PMID: 8288053 [PubMed - indexed for MEDLINE]Related articles
Type I diabetes mellitus does not alter initial splanchnic glucose extraction or hepatic UDP-glucose flux during enteral glucose administration.
Vella A, Shah P, Basu R, Basu A, Camilleri M, Schwenk WF, Rizza RA.
Diabetologia. 2001 Jun;44(6):729-37.PMID: 11440366 [PubMed - indexed for MEDLINE]Related articles
Both fasting glucose production and disappearance are abnormal in people with "mild" and "severe" type 2 diabetes.
Basu R, Schwenk WF, Rizza RA.
Am J Physiol Endocrinol Metab. 2004 Jul;287(1):E55-62. Epub 2004 Feb 24.PMID: 14982753 [PubMed - indexed for MEDLINE]Related articlesFree article
Effects of free fatty acids and glycerol on splanchnic glucose metabolism and insulin extraction in nondiabetic humans.
Shah P, Vella A, Basu A, Basu R, Adkins A, Schwenk WF, Johnson CM, Nair KS, Jensen MD, Rizza RA.
Diabetes. 2002 Feb;51(2):301-10.PMID: 11812736 [PubMed - indexed for MEDLINE]Related articlesFree article
Lack of effect of exendin-4 and glucagon-like peptide-1-(7,36)-amide on insulin action in non-diabetic humans.
Vella A, Shah P, Reed AS, Adkins AS, Basu R, Rizza RA.
Diabetologia. 2002 Oct;45(10):1410-5. Epub 2002 Sep 5. Erratum in: Diabetologia. 2003 Nov;46(11):1589. PMID: 12378382 [PubMed - indexed for MEDLINE]Related articles
Effects of type 2 diabetes on insulin secretion, insulin action, glucose effectiveness, and postprandial glucose metabolism.
Basu A, Dalla Man C, Basu R, Toffolo G, Cobelli C, Rizza RA.
Diabetes Care. 2009 May;32(5):866-72. Epub 2009 Feb 5.PMID: 19196896 [PubMed - indexed for MEDLINE]Related articlesFree article
Assessment of hepatic sensitivity to glucagon in NIDDM: use as a tool to estimate the contribution of the indirect pathway to nocturnal glycogen synthesis.
Nielsen MF, Wise S, Dinneen SF, Schwenk WF, Basu A, Rizza RA.
Diabetes. 1997 Dec;46(12):2007-16.PMID: 9392488 [PubMed - indexed for MEDLINE]Related articles
Differential effects of acute and extended infusions of glucagon-like peptide-1 on first- and second-phase insulin secretion in diabetic and nondiabetic humans.
Quddusi S, Vahl TP, Hanson K, Prigeon RL, D'Alessio DA.
Diabetes Care. 2003 Mar;26(3):791-8.PMID: 12610039 [PubMed - indexed for MEDLINE]Related articlesFree article
Abnormal meal carbohydrate disposition in insulin-dependent diabetes. Relative contributions of endogenous glucose production and initial splanchnic uptake and effect of intensive insulin therapy.
Pehling G, Tessari P, Gerich JE, Haymond MW, Service FJ, Rizza RA.
J Clin Invest. 1984 Sep;74(3):985-91.PMID: 6381541 [PubMed - indexed for MEDLINE]Related articlesFree article
Comparison of the effects of pioglitazone and metformin on hepatic and extra-hepatic insulin action in people with type 2 diabetes.
Basu R, Shah P, Basu A, Norby B, Dicke B, Chandramouli V, Cohen O, Landau BR, Rizza RA.
Diabetes. 2008 Jan;57(1):24-31. Epub 2007 Oct 3.PMID: 17914032 [PubMed - indexed for MEDLINE]Related articlesFree article
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