PubMed

Hyperresponsiveness, resistance to B-cell receptor-dependent activation-induced cell death, and accumulation of hyperactivated B-cells in islets is associated with the onset of insulitis but not type 1 diabetes.

Hussain S, Salojin KV, Delovitch TL.

Diabetes. 2004 Aug;53(8):2003-11.PMID: 15277379 [PubMed - indexed for MEDLINE]Related articlesFree article

Dysregulated B7-1 and B7-2 expression on nonobese diabetic mouse B cells is associated with increased T cell costimulation and the development of insulitis.

Hussain S, Delovitch TL.

J Immunol. 2005 Jan 15;174(2):680-7.PMID: 15634886 [PubMed - indexed for MEDLINE]Related articlesFree article

In vitro xenorecognition of adult pig pancreatic islet cells by splenocytes from nonobese diabetic or non-diabetes-prone mice.

Rivereau AS, You S, Lalain S, Gouin E, Saï P.

Transplantation. 1998 Sep 15;66(5):633-8.PMID: 9753345 [PubMed - indexed for MEDLINE]Related articles

Intravenous transfusion of BCR-activated B cells protects NOD mice from type 1 diabetes in an IL-10-dependent manner.

Hussain S, Delovitch TL.

J Immunol. 2007 Dec 1;179(11):7225-32.PMID: 18025164 [PubMed - indexed for MEDLINE]Related articlesFree article

B-cells are required for the initiation of insulitis and sialitis in nonobese diabetic mice.

Noorchashm H, Noorchashm N, Kern J, Rostami SY, Barker CF, Naji A.

Diabetes. 1997 Jun;46(6):941-6.PMID: 9166663 [PubMed - indexed for MEDLINE]Related articles

Impaired activation of islet-reactive CD4 T cells in pancreatic lymph nodes of B cell-deficient nonobese diabetic mice.

Greeley SA, Moore DJ, Noorchashm H, Noto LE, Rostami SY, Schlachterman A, Song HK, Koeberlein B, Barker CF, Naji A.

J Immunol. 2001 Oct 15;167(8):4351-7.PMID: 11591759 [PubMed - indexed for MEDLINE]Related articlesFree article

Islet-specific expression of IL-10 promotes diabetes in nonobese diabetic mice independent of Fas, perforin, TNF receptor-1, and TNF receptor-2 molecules.

Balasa B, Van Gunst K, Jung N, Balakrishna D, Santamaria P, Hanafusa T, Itoh N, Sarvetnick N.

J Immunol. 2000 Sep 1;165(5):2841-9.PMID: 10946317 [PubMed - indexed for MEDLINE]Related articlesFree article

Perturbed homeostasis of peripheral T cells elicits decreased susceptibility to anti-CD3-induced apoptosis in prediabetic nonobese diabetic mice.

Yang W, Hussain S, Mi QS, Santamaria P, Delovitch TL.

J Immunol. 2004 Oct 1;173(7):4407-16.PMID: 15383571 [PubMed - indexed for MEDLINE]Related articlesFree article

Local production of human IL-6 promotes insulitis but retards the onset of insulin-dependent diabetes mellitus in non-obese diabetic mice.

DiCosmo BF, Picarella D, Flavell RA.

Int Immunol. 1994 Dec;6(12):1829-37.PMID: 7696203 [PubMed - indexed for MEDLINE]Related articles

Insulin-dependent diabetes in the NOD mouse model. I. Detection and characterization of autoantibody bound to the surface of pancreatic beta cells prior to development of the insulitis lesion in prediabetic NOD mice.

Shieh DC, Cornelius JG, Winter WE, Peck AB.

Autoimmunity. 1993;15(2):123-35.PMID: 8218837 [PubMed - indexed for MEDLINE]Related articles

Islet-specific T cell clones transfer diabetes to nonobese diabetic (NOD) F1 mice.

Peterson JD, Pike B, McDuffie M, Haskins K.

J Immunol. 1994 Sep 15;153(6):2800-6.PMID: 8077683 [PubMed - indexed for MEDLINE]Related articles

Development of insulitis and diabetes in B cell-deficient NOD mice.

Yang M, Charlton B, Gautam AM.

J Autoimmun. 1997 Jun;10(3):257-60.PMID: 9218752 [PubMed - indexed for MEDLINE]Related articles

Differential impact of T cell repertoire diversity in diabetes-prone or -resistant IL-10 transgenic mice.

Balasa B, Lee J, Sarvetnick N.

Cell Immunol. 1999 May 1;193(2):170-8.PMID: 10222059 [PubMed - indexed for MEDLINE]Related articles

Direct evidence for the contribution of B cells to the progression of insulitis and the development of diabetes in non-obese diabetic mice.

Akashi T, Nagafuchi S, Anzai K, Kondo S, Kitamura D, Wakana S, Ono J, Kikuchi M, Niho Y, Watanabe T.

Int Immunol. 1997 Aug;9(8):1159-64.PMID: 9263013 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired CD4 T cell activation due to reliance upon B cell-mediated costimulation in nonobese diabetic (NOD) mice.

Noorchashm H, Moore DJ, Noto LE, Noorchashm N, Reed AJ, Reed AL, Song HK, Mozaffari R, Jevnikar AM, Barker CF, Naji A.

J Immunol. 2000 Oct 15;165(8):4685-96.PMID: 11035112 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytokines activate caspase-3 in insulinoma cells of diabetes-prone NOD mice directly and via upregulation of Fas.

Augstein P, Bahr J, Wachlin G, Heinke P, Berg S, Salzsieder E, Harrison LC.

J Autoimmun. 2004 Dec;23(4):301-9.PMID: 15571924 [PubMed - indexed for MEDLINE]Related articles

Rotavirus infection accelerates type 1 diabetes in mice with established insulitis.

Graham KL, Sanders N, Tan Y, Allison J, Kay TW, Coulson BS.

J Virol. 2008 Jul;82(13):6139-49. Epub 2008 Apr 16.PMID: 18417562 [PubMed - indexed for MEDLINE]Related articlesFree article

CD4+CD25+ regulatory T cells control the progression from periinsulitis to destructive insulitis in murine autoimmune diabetes.

Ott PA, Anderson MR, Tary-Lehmann M, Lehmann PV.

Cell Immunol. 2005 May;235(1):1-11. Epub 2005 Aug 24.PMID: 16122720 [PubMed - indexed for MEDLINE]Related articles

Mucosa-associated (beta 7-integrinhigh) lymphocytes accumulate early in the pancreas of NOD mice and show aberrant recirculation behavior.

Hänninen A, Salmi M, Simell O, Jalkanen S.

Diabetes. 1996 Sep;45(9):1173-80.PMID: 8772718 [PubMed - indexed for MEDLINE]Related articles

Deficient activation and resistance to activation-induced apoptosis of CD8+ T cells is associated with defective peripheral tolerance in nonobese diabetic mice.

Arreaza G, Salojin K, Yang W, Zhang J, Gill B, Mi QS, Gao JX, Meagher C, Cameron M, Delovitch TL.

Clin Immunol. 2003 May;107(2):103-15.PMID: 12763479 [PubMed - indexed for MEDLINE]Related articles