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    Results: 1 to 20 of 125

    1.

    GAD65-specific CD4+ T-cells with high antigen avidity are prevalent in peripheral blood of patients with type 1 diabetes.

    Reijonen H, Mallone R, Heninger AK, Laughlin EM, Kochik SA, Falk B, Kwok WW, Greenbaum C, Nepom GT.

    Diabetes. 2004 Aug;53(8):1987-94.PMID: 15277377 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    GAD65- and proinsulin-specific CD4+ T-cells detected by MHC class II tetramers in peripheral blood of type 1 diabetes patients and at-risk subjects.

    Oling V, Marttila J, Ilonen J, Kwok WW, Nepom G, Knip M, Simell O, Reijonen H.

    J Autoimmun. 2005 Nov;25(3):235-43. Epub 2005 Nov 2. Erratum in: J Autoimmun. 2006 Aug;27(1):69. PMID: 16263242 [PubMed - indexed for MEDLINE]Related articles

    3.

    Soluble, dimeric HLA DR4-peptide chimeras: an approach for detection and immunoregulation of human type-1 diabetes.

    Preda I, McEvoy RC, Lin M, Bona CA, Rapaport R, Brumeanu TD, Casares S.

    Eur J Immunol. 2005 Sep;35(9):2762-75.PMID: 16106371 [PubMed - indexed for MEDLINE]Related articles

    4.

    Detection of GAD65-specific T-cells by major histocompatibility complex class II tetramers in type 1 diabetic patients and at-risk subjects.

    Reijonen H, Novak EJ, Kochik S, Heninger A, Liu AW, Kwok WW, Nepom GT.

    Diabetes. 2002 May;51(5):1375-82.PMID: 11978633 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Comparative study of GAD65-specific CD4+ T cells in healthy and type 1 diabetic subjects.

    Danke NA, Yang J, Greenbaum C, Kwok WW.

    J Autoimmun. 2005 Dec;25(4):303-11. Epub 2005 Oct 24.PMID: 16249070 [PubMed - indexed for MEDLINE]Related articles

    6.

    Differential recognition and activation thresholds in human autoreactive GAD-specific T-cells.

    Mallone R, Kochik SA, Laughlin EM, Gersuk VH, Reijonen H, Kwok WW, Nepom GT.

    Diabetes. 2004 Apr;53(4):971-7.PMID: 15047612 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Complexity of human immune response profiles for CD4+ T cell epitopes from the diabetes autoantigen GAD65.

    Masewicz SA, Meldrum N, Gersuk V, Gaur L, Hagopian W, Moriarity L, Nepom GT.

    Autoimmunity. 2001;34(4):231-40.PMID: 11905849 [PubMed - indexed for MEDLINE]Related articles

    8.

    Pro- and anti-inflammatory cytokine production by autoimmune T cells against preproinsulin in HLA-DRB1*04, DQ8 Type 1 diabetes.

    Durinovic-Belló I, Schlosser M, Riedl M, Maisel N, Rosinger S, Kalbacher H, Deeg M, Ziegler M, Elliott J, Roep BO, Karges W, Boehm BO.

    Diabetologia. 2004 Mar;47(3):439-50. Epub 2004 Jan 24.PMID: 14745491 [PubMed - indexed for MEDLINE]Related articles

    9.

    Changes in autoreactive T cell avidity during type 1 diabetes development.

    Standifer NE, Burwell EA, Gersuk VH, Greenbaum CJ, Nepom GT.

    Clin Immunol. 2009 Sep;132(3):312-20. Epub 2009 May 23.PMID: 19482555 [PubMed - indexed for MEDLINE]Related articles

    10.

    Autoreactive T cells in healthy individuals.

    Danke NA, Koelle DM, Yee C, Beheray S, Kwok WW.

    J Immunol. 2004 May 15;172(10):5967-72.PMID: 15128778 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Functional avidity directs T-cell fate in autoreactive CD4+ T cells.

    Mallone R, Kochik SA, Reijonen H, Carson B, Ziegler SF, Kwok WW, Nepom GT.

    Blood. 2005 Oct 15;106(8):2798-805. Epub 2005 Jul 19.PMID: 16030184 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Low-avidity recognition by CD4+ T cells directed to self-antigens.

    Gebe JA, Falk BA, Rock KA, Kochik SA, Heninger AK, Reijonen H, Kwok WW, Nepom GT.

    Eur J Immunol. 2003 May;33(5):1409-17.PMID: 12731068 [PubMed - indexed for MEDLINE]Related articles

    13.

    Characterization of preparations of GAD65, proinsulin, and the islet tyrosine phosphatase IA-2 for use in detection of autoreactive T-cells in type 1 diabetes: report of phase II of the Second International Immunology of Diabetes Society Workshop for Standardization of T-cell assays in type 1 diabetes.

    Peakman M, Tree TI, Endl J, van Endert P, Atkinson MA, Roep BO; Second International Immunology of Diabetes Society Workshop for Standardization ot T-cell Assays in Type 1 Diabetes.

    Diabetes. 2001 Aug;50(8):1749-54.PMID: 11473034 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Characterization of self-glutamic acid decarboxylase 65-reactive CD4+ T-cell clones established from Japanese patients with insulin-dependent diabetes mellitus.

    Tabata H, Kanai T, Yoshizumi H, Nishiyama S, Fujimoto S, Matsuda I, Yasukawa M, Matsushita S, Nishimura Y.

    Hum Immunol. 1998 Sep;59(9):549-60.PMID: 9757911 [PubMed - indexed for MEDLINE]Related articles

    15.

    Class II major histocompatibility complex-peptide tetramer staining in relation to functional avidity and T cell receptor diversity in the mouse CD4(+) T cell response to a rheumatoid arthritis-associated antigen.

    Falta MT, Fontenot AP, Rosloniec EF, Crawford F, Roark CL, Bill J, Marrack P, Kappler J, Kotzin BL.

    Arthritis Rheum. 2005 Jun;52(6):1885-96.PMID: 15934080 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    In vitro stimulation with glutamic acid decarboxylase (GAD65) leads to an oligoclonal response of peripheral T-cells in an IDDM patient.

    Weiss U, Manfras BJ, Terjung D, Eiermann T, Wölpl A, Löliger C, Kühnl P, Boehm BO.

    Scand J Immunol. 1995 Dec;42(6):673-8.PMID: 8552991 [PubMed - indexed for MEDLINE]Related articles

    17.

    Modeling competition among autoreactive CD8+ T cells in autoimmune diabetes: implications for antigen-specific therapy.

    Marée AF, Santamaria P, Edelstein-Keshet L.

    Int Immunol. 2006 Jul;18(7):1067-77. Epub 2006 May 25.PMID: 16728432 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Recurrence of autoreactive antigen-specific CD4+ T cells in autoimmune diabetes after pancreas transplantation.

    Laughlin E, Burke G, Pugliese A, Falk B, Nepom G.

    Clin Immunol. 2008 Jul;128(1):23-30. Epub 2008 May 2.PMID: 18455963 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    CD8+ suppressor-mediated regulation of human CD4+ T cell responses to glutamic acid decarboxylase 65.

    James EA, Kwok WW.

    Eur J Immunol. 2007 Jan;37(1):78-86.PMID: 17163450 [PubMed - indexed for MEDLINE]Related articles

    20.

    Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cells.

    Kim SK, Tarbell KV, Sanna M, Vadeboncoeur M, Warganich T, Lee M, Davis M, McDevitt HO.

    Proc Natl Acad Sci U S A. 2004 Sep 28;101(39):14204-9. Epub 2004 Sep 20.PMID: 15381770 [PubMed - indexed for MEDLINE]Related articlesFree article

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