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    Results: 1 to 20 of 283

    1.

    Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus.

    McCrimmon RJ, Fan X, Ding Y, Zhu W, Jacob RJ, Sherwin RS.

    Diabetes. 2004 Aug;53(8):1953-8.PMID: 15277372 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Hypothalamic AMP-activated protein kinase activation with AICAR amplifies counterregulatory responses to hypoglycemia in a rodent model of type 1 diabetes.

    Fan X, Ding Y, Brown S, Zhou L, Shaw M, Vella MC, Cheng H, McNay EC, Sherwin RS, McCrimmon RJ.

    Am J Physiol Regul Integr Comp Physiol. 2009 Jun;296(6):R1702-8. Epub 2009 Apr 8.PMID: 19357294 [PubMed - indexed for MEDLINE]Related articles

    3.

    Portal venous 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion overcomes hyperinsulinemic suppression of endogenous glucose output.

    Camacho RC, Pencek RR, Lacy DB, James FD, Donahue EP, Wasserman DH.

    Diabetes. 2005 Feb;54(2):373-82.PMID: 15677495 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Activation of AMP-activated protein kinase within the ventromedial hypothalamus amplifies counterregulatory hormone responses in rats with defective counterregulation.

    McCrimmon RJ, Fan X, Cheng H, McNay E, Chan O, Shaw M, Ding Y, Zhu W, Sherwin RS.

    Diabetes. 2006 Jun;55(6):1755-60.PMID: 16731839 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Key role for AMP-activated protein kinase in the ventromedial hypothalamus in regulating counterregulatory hormone responses to acute hypoglycemia.

    McCrimmon RJ, Shaw M, Fan X, Cheng H, Ding Y, Vella MC, Zhou L, McNay EC, Sherwin RS.

    Diabetes. 2008 Feb;57(2):444-50. Epub 2007 Oct 31.PMID: 17977955 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Role of hypothalamic adenosine 5'-monophosphate-activated protein kinase in the impaired counterregulatory response induced by repetitive neuroglucopenia.

    Alquier T, Kawashima J, Tsuji Y, Kahn BB.

    Endocrinology. 2007 Mar;148(3):1367-75. Epub 2006 Dec 21.PMID: 17185376 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Blockade of GABA(A) receptors in the ventromedial hypothalamus further stimulates glucagon and sympathoadrenal but not the hypothalamo-pituitary-adrenal response to hypoglycemia.

    Chan O, Zhu W, Ding Y, McCrimmon RJ, Sherwin RS.

    Diabetes. 2006 Apr;55(4):1080-7.PMID: 16567532 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Local lactate perfusion of the ventromedial hypothalamus suppresses hypoglycemic counterregulation.

    Borg MA, Tamborlane WV, Shulman GI, Sherwin RS.

    Diabetes. 2003 Mar;52(3):663-6.PMID: 12606506 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    AMP-activated protein kinase and nitric oxide regulate the glucose sensitivity of ventromedial hypothalamic glucose-inhibited neurons.

    Murphy BA, Fakira KA, Song Z, Beuve A, Routh VH.

    Am J Physiol Cell Physiol. 2009 Sep;297(3):C750-8. Epub 2009 Jul 1.PMID: 19570894 [PubMed - indexed for MEDLINE]Related articles

    10.

    Glucose, insulin, and leptin signaling pathways modulate nitric oxide synthesis in glucose-inhibited neurons in the ventromedial hypothalamus.

    Canabal DD, Song Z, Potian JG, Beuve A, McArdle JJ, Routh VH.

    Am J Physiol Regul Integr Comp Physiol. 2007 Apr;292(4):R1418-28. Epub 2006 Dec 14.PMID: 17170237 [PubMed - indexed for MEDLINE]Related articles

    11.

    Activation of ATP-sensitive K+ channels in the ventromedial hypothalamus amplifies counterregulatory hormone responses to hypoglycemia in normal and recurrently hypoglycemic rats.

    McCrimmon RJ, Evans ML, Fan X, McNay EC, Chan O, Ding Y, Zhu W, Gram DX, Sherwin RS.

    Diabetes. 2005 Nov;54(11):3169-74.PMID: 16249441 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Hypothalamic ATP-sensitive K + channels play a key role in sensing hypoglycemia and triggering counterregulatory epinephrine and glucagon responses.

    Evans ML, McCrimmon RJ, Flanagan DE, Keshavarz T, Fan X, McNay EC, Jacob RJ, Sherwin RS.

    Diabetes. 2004 Oct;53(10):2542-51.PMID: 15448082 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats.

    Borg MA, Sherwin RS, Borg WP, Tamborlane WV, Shulman GI.

    J Clin Invest. 1997 Jan 15;99(2):361-5.PMID: 9006005 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    AMPK activation with AICAR provokes an acute fall in plasma [K+].

    Zheng D, Perianayagam A, Lee DH, Brannan MD, Yang LE, Tellalian D, Chen P, Lemieux K, Marette A, Youn JH, McDonough AA.

    Am J Physiol Cell Physiol. 2008 Jan;294(1):C126-35. Epub 2007 Nov 14.PMID: 18003746 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Insulin blunts the response of glucose-excited neurons in the ventrolateral-ventromedial hypothalamic nucleus to decreased glucose.

    Cotero VE, Routh VH.

    Am J Physiol Endocrinol Metab. 2009 May;296(5):E1101-9. Epub 2009 Feb 17. Erratum in: Am J Physiol Endocrinol Metab. 2009 Aug;297(2):E560-1. PMID: 19223652 [PubMed - indexed for MEDLINE]Related articles

    16.

    AICAR and phlorizin reverse the hypoglycemia-specific defect in glucagon secretion in the diabetic BB rat.

    McCrimmon RJ, Evans ML, Jacob RJ, Fan X, Zhu Y, Shulman GI, Sherwin RS.

    Am J Physiol Endocrinol Metab. 2002 Nov;283(5):E1076-83.PMID: 12376337 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Chronic hypoglycemia and diabetes impair counterregulation induced by localized 2-deoxy-glucose perfusion of the ventromedial hypothalamus in rats.

    Borg MA, Borg WP, Tamborlane WV, Brines ML, Shulman GI, Sherwin RS.

    Diabetes. 1999 Mar;48(3):584-7.PMID: 10078560 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Hypothalamic AMP-activated protein kinase mediates counter-regulatory responses to hypoglycaemia in rats.

    Han SM, Namkoong C, Jang PG, Park IS, Hong SW, Katakami H, Chun S, Kim SW, Park JY, Lee KU, Kim MS.

    Diabetologia. 2005 Oct;48(10):2170-8. Epub 2005 Aug 23.PMID: 16132951 [PubMed - indexed for MEDLINE]Related articles

    19.

    Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia.

    Borg WP, During MJ, Sherwin RS, Borg MA, Brines ML, Shulman GI.

    J Clin Invest. 1994 Apr;93(4):1677-82.PMID: 8163668 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside causes acute hepatic insulin resistance in vivo.

    Pencek RR, Shearer J, Camacho RC, James FD, Lacy DB, Fueger PT, Donahue EP, Snead W, Wasserman DH.

    Diabetes. 2005 Feb;54(2):355-60.PMID: 15677492 [PubMed - indexed for MEDLINE]Related articlesFree article

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