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    Results: 1 to 20 of 130

    1.

    Does the glucose-dependent insulin secretion mechanism itself cause oxidative stress in pancreatic beta-cells?

    Fridlyand LE, Philipson LH.

    Diabetes. 2004 Aug;53(8):1942-8. Review.PMID: 15277370 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Nicotinamide nucleotide transhydrogenase: a link between insulin secretion, glucose metabolism and oxidative stress.

    Freeman H, Shimomura K, Cox RD, Ashcroft FM.

    Biochem Soc Trans. 2006 Nov;34(Pt 5):806-10.PMID: 17052203 [PubMed - indexed for MEDLINE]Related articles

    3.

    Mitochondrial reactive oxygen species reduce insulin secretion by pancreatic beta-cells.

    Sakai K, Matsumoto K, Nishikawa T, Suefuji M, Nakamaru K, Hirashima Y, Kawashima J, Shirotani T, Ichinose K, Brownlee M, Araki E.

    Biochem Biophys Res Commun. 2003 Jan 3;300(1):216-22.PMID: 12480546 [PubMed - indexed for MEDLINE]Related articles

    4.

    D-Glyceraldehyde causes production of intracellular peroxide in pancreatic islets, oxidative stress, and defective beta cell function via non-mitochondrial pathways.

    Takahashi H, Tran PO, LeRoy E, Harmon JS, Tanaka Y, Robertson RP.

    J Biol Chem. 2004 Sep 3;279(36):37316-23. Epub 2004 Jun 22.PMID: 15213233 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Sulfonylurea as well as elevated glucose levels stimulate reactive oxygen species production in the pancreatic beta-cell line, MIN6-a role of NAD(P)H oxidase in beta-cells.

    Tsubouchi H, Inoguchi T, Inuo M, Kakimoto M, Sonta T, Sonoda N, Sasaki S, Kobayashi K, Sumimoto H, Nawata H.

    Biochem Biophys Res Commun. 2005 Jan 7;326(1):60-5.PMID: 15567152 [PubMed - indexed for MEDLINE]Related articles

    6.

    Probucol preserves pancreatic beta-cell function through reduction of oxidative stress in type 2 diabetes.

    Gorogawa S, Kajimoto Y, Umayahara Y, Kaneto H, Watada H, Kuroda A, Kawamori D, Yasuda T, Matsuhisa M, Yamasaki Y, Hori M.

    Diabetes Res Clin Pract. 2002 Jul;57(1):1-10.PMID: 12007724 [PubMed - indexed for MEDLINE]Related articles

    7.

    Contribution of glycolytic and mitochondrial pathways in glucose-induced changes in islet respiration and insulin secretion.

    Ortsäter H, Liss P, Akerman KE, Bergsten P.

    Pflugers Arch. 2002 Jul;444(4):506-12. Epub 2002 Jun 8.PMID: 12136270 [PubMed - indexed for MEDLINE]Related articles

    8.

    Mutated ATP synthase induces oxidative stress and impaired insulin secretion in beta-cells of female BHE/cdb rats.

    Saleh MC, Fatehi-Hassanabad Z, Wang R, Nino-Fong R, Wadowska DW, Wright GM, Harper ME, Chan CB.

    Diabetes Metab Res Rev. 2008 Jul-Aug;24(5):392-403.PMID: 18273840 [PubMed - indexed for MEDLINE]Related articles

    9.

    Oxidative stress is a mediator of glucose toxicity in insulin-secreting pancreatic islet cell lines.

    Wu L, Nicholson W, Knobel SM, Steffner RJ, May JM, Piston DW, Powers AC.

    J Biol Chem. 2004 Mar 26;279(13):12126-34. Epub 2003 Dec 19.PMID: 14688272 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Selective loss of glucose-induced amplification of insulin secretion in mouse pancreatic islets pretreated with sulfonylurea in the absence of fuels.

    Urban KA, Panten U.

    Diabetologia. 2005 Dec;48(12):2563-6. Epub 2005 Nov 11.PMID: 16283243 [PubMed - indexed for MEDLINE]Related articles

    11.

    The influence of genetic background on the induction of oxidative stress and impaired insulin secretion in mouse islets.

    Zraika S, Aston-Mourney K, Laybutt DR, Kebede M, Dunlop ME, Proietto J, Andrikopoulos S.

    Diabetologia. 2006 Jun;49(6):1254-63. Epub 2006 Mar 29.PMID: 16570159 [PubMed - indexed for MEDLINE]Related articles

    12.

    Insulin secretion defects of human type 2 diabetic islets are corrected in vitro by a new reactive oxygen species scavenger.

    Lupi R, Del Guerra S, Mancarella R, Novelli M, Valgimigli L, Pedulli GF, Paolini M, Soleti A, Filipponi F, Mosca F, Boggi U, Del Prato S, Masiello P, Marchetti P.

    Diabetes Metab. 2007 Nov;33(5):340-5. Epub 2007 Jul 9.PMID: 17616474 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    HIV-1 protease inhibitor induced oxidative stress suppresses glucose stimulated insulin release: protection with thymoquinone.

    Chandra S, Mondal D, Agrawal KC.

    Exp Biol Med (Maywood). 2009 Apr;234(4):442-53. Epub 2009 Feb 20.PMID: 19234050 [PubMed - indexed for MEDLINE]Related articles

    14.

    Chronic exposure to beta-hydroxybutyrate inhibits glucose-induced insulin release from pancreatic islets by decreasing NADH contents.

    Takehiro M, Fujimoto S, Shimodahira M, Shimono D, Mukai E, Nabe K, Radu RG, Kominato R, Aramaki Y, Seino Y, Yamada Y.

    Am J Physiol Endocrinol Metab. 2005 Feb;288(2):E372-80. Epub 2004 Oct 12.PMID: 15479955 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Src activation generates reactive oxygen species and impairs metabolism-secretion coupling in diabetic Goto-Kakizaki and ouabain-treated rat pancreatic islets.

    Kominato R, Fujimoto S, Mukai E, Nakamura Y, Nabe K, Shimodahira M, Nishi Y, Funakoshi S, Seino Y, Inagaki N.

    Diabetologia. 2008 Jul;51(7):1226-35. Epub 2008 May 1.PMID: 18449527 [PubMed - indexed for MEDLINE]Related articles

    16.

    Adenoviral overexpression of the glutamylcysteine ligase catalytic subunit protects pancreatic islets against oxidative stress.

    Tran PO, Parker SM, LeRoy E, Franklin CC, Kavanagh TJ, Zhang T, Zhou H, Vliet P, Oseid E, Harmon JS, Robertson RP.

    J Biol Chem. 2004 Dec 24;279(52):53988-93. Epub 2004 Oct 12.PMID: 15485876 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    [Anatomical and functional plasticity of pancreatic beta-cells and type 2 diabetes]

    Cerasi E, Ktorza A.

    Med Sci (Paris). 2007 Oct;23(10):885-94. Review. French. PMID: 17937902 [PubMed - indexed for MEDLINE]Related articles

    18.

    Glucose-regulated glucagon secretion requires insulin receptor expression in pancreatic alpha-cells.

    Diao J, Asghar Z, Chan CB, Wheeler MB.

    J Biol Chem. 2005 Sep 30;280(39):33487-96. Epub 2005 Jul 14.PMID: 16027126 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Anaplerosis via pyruvate carboxylase is required for the fuel-induced rise in the ATP:ADP ratio in rat pancreatic islets.

    Fransson U, Rosengren AH, Schuit FC, Renström E, Mulder H.

    Diabetologia. 2006 Jul;49(7):1578-86. Epub 2006 Apr 26.PMID: 16752176 [PubMed - indexed for MEDLINE]Related articles

    20.

    Pharmacological interventions that directly stimulate or modulate insulin secretion from pancreatic beta-cell: implications for the treatment of type 2 diabetes.

    Farret A, Lugo-Garcia L, Galtier F, Gross R, Petit P.

    Fundam Clin Pharmacol. 2005 Dec;19(6):647-56. Review.PMID: 16313276 [PubMed - indexed for MEDLINE]Related articles

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