Warning: The NCBI web site requires JavaScript to function. more...
Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis.
Kojima F, Naraba H, Miyamoto S, Beppu M, Aoki H, Kawai S.
Arthritis Res Ther. 2004;6(4):R355-65. Epub 2004 Jun 8.
Related citations
Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes.
Li X, Afif H, Cheng S, Martel-Pelletier J, Pelletier JP, Ranger P, Fahmi H.
J Rheumatol. 2005 May;32(5):887-95.
Coexpression of microsomal prostaglandin E synthase with cyclooxygenase-2 in human rheumatoid synovial cells.
Kojima F, Naraba H, Sasaki Y, Okamoto R, Koshino T, Kawai S.
J Rheumatol. 2002 Sep;29(9):1836-42.
Prostaglandin E2 synthesis in cartilage explants under compression: mPGES-1 is a mechanosensitive gene.
Gosset M, Berenbaum F, Levy A, Pigenet A, Thirion S, Saffar JL, Jacques C.
Arthritis Res Ther. 2006;8(4):R135.
Prostaglandin E2 is an enhancer of interleukin-1beta-induced expression of membrane-associated prostaglandin E synthase in rheumatoid synovial fibroblasts.
Kojima F, Naraba H, Sasaki Y, Beppu M, Aoki H, Kawai S.
Arthritis Rheum. 2003 Oct;48(10):2819-28.
Regulation of prostaglandin E(2) synthesis in cells derived from chondrocytes of patients with osteoarthritis.
Shimpo H, Sakai T, Kondo S, Mishima S, Yoda M, Hiraiwa H, Ishiguro N.
J Orthop Sci. 2009 Sep;14(5):611-7. Epub 2009 Oct 3.
Up-regulation of microsomal prostaglandin E synthase 1 in osteoarthritic human cartilage: critical roles of the ERK-1/2 and p38 signaling pathways.
Masuko-Hongo K, Berenbaum F, Humbert L, Salvat C, Goldring MB, Thirion S.
Arthritis Rheum. 2004 Sep;50(9):2829-38.
Evaluation of coexpression of microsomal prostaglandin E synthase-1 and cyclooxygenase-2 in interleukin-1-stimulated equine articular chondrocytes.
Farley J, Sirois J, MacFarlane PH, Kombé A, Laverty S.
Am J Vet Res. 2005 Nov;66(11):1985-91.
Contrasting effects of peroxisome-proliferator-activated receptor (PPAR)gamma agonists on membrane-associated prostaglandin E2 synthase-1 in IL-1beta-stimulated rat chondrocytes: evidence for PPARgamma-independent inhibition by 15-deoxy-Delta12,14prostaglandin J2.
Bianchi A, Moulin D, Sebillaud S, Koufany M, Galteau MM, Netter P, Terlain B, Jouzeau JY.
Arthritis Res Ther. 2005;7(6):R1325-37. Epub 2005 Sep 22.
Microsomal prostaglandin E synthase is regulated by proinflammatory cytokines and glucocorticoids in primary rheumatoid synovial cells.
Stichtenoth DO, Thorén S, Bian H, Peters-Golden M, Jakobsson PJ, Crofford LJ.
J Immunol. 2001 Jul 1;167(1):469-74.
Long-term NSAID treatment directly decreases COX-2 and mPGES-1 production in the articular cartilage of patients with osteoarthritis.
Alvarez-Soria MA, Herrero-Beaumont G, Moreno-Rubio J, Calvo E, Santillana J, Egido J, Largo R.
Osteoarthritis Cartilage. 2008 Dec;16(12):1484-93. Epub 2008 Jun 10.
Microsomal prostaglandin E synthase (mPGES)-1, mPGES-2 and cytosolic PGES expression in human gastritis and gastric ulcer tissue.
Gudis K, Tatsuguchi A, Wada K, Futagami S, Nagata K, Hiratsuka T, Shinji Y, Miyake K, Tsukui T, Fukuda Y, Sakamoto C.
Lab Invest. 2005 Feb;85(2):225-36.
Hypoxia-inducible factor 1alpha is involved in the prostaglandin metabolism of osteoarthritic cartilage through up-regulation of microsomal prostaglandin E synthase 1 in articular chondrocytes.
Grimmer C, Pfander D, Swoboda B, Aigner T, Mueller L, Hennig FF, Gelse K.
Arthritis Rheum. 2007 Dec;56(12):4084-94.
Induced microsomal PGE synthase-1 is involved in cyclooxygenase-2-dependent PGE2 production in gastric fibroblasts.
Shinji Y, Tsukui T, Tatsuguchi A, Shinoki K, Kusunoki M, Suzuki K, Hiratsuka T, Wada K, Futagami S, Miyake K, Gudis K, Sakamoto C.
Am J Physiol Gastrointest Liver Physiol. 2005 Feb;288(2):G308-15. Epub 2004 Sep 30.
IL-1beta treatment does not co-ordinately up-regulate mPGES-1 and COX-2 mRNA expression, but results in higher degree of cellular and intracellular co-localization of their immunoreactive proteins in human placenta trophoblast cells.
Premyslova M, Chisaka H, Okamura K, Challis JR.
Placenta. 2006 Jun-Jul;27(6-7):576-86. Epub 2005 Sep 22.
Crucial role of visfatin/pre-B cell colony-enhancing factor in matrix degradation and prostaglandin E2 synthesis in chondrocytes: possible influence on osteoarthritis.
Gosset M, Berenbaum F, Salvat C, Sautet A, Pigenet A, Tahiri K, Jacques C.
Arthritis Rheum. 2008 May;58(5):1399-409.
Microsomal prostaglandin E synthase-1, which is not coupled to a particular cyclooxygenase isoenzyme, is essential for prostaglandin E(2) biosynthesis in vascular smooth muscle cells.
Camacho M, Gerbolés E, Escudero JR, Antón R, García-Moll X, Vila L.
J Thromb Haemost. 2007 Jul;5(7):1411-9. Epub 2007 Mar 31.
Induction of cyclo-oxygenase-2 by cytokines in human cultured airway smooth muscle cells: novel inflammatory role of this cell type.
Belvisi MG, Saunders MA, Haddad el-B, Hirst SJ, Yacoub MH, Barnes PJ, Mitchell JA.
Br J Pharmacol. 1997 Mar;120(5):910-6.
Regulation of prostaglandin E synthases: effects of siRNA-mediated inhibition of microsomal prostaglandin E synthase-1.
Båge T, Modéer T, Kawakami T, Quezada HC, Yucel-Lindberg T.
Biochim Biophys Acta. 2007 Oct;1773(10):1589-98. Epub 2007 Aug 2.
Increased expression of lipocalin-type prostaglandin D2 synthase in osteoarthritic cartilage.
Zayed N, Li X, Chabane N, Benderdour M, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H.
Arthritis Res Ther. 2008;10(6):R146. Epub 2008 Dec 18.
Filter your results:
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on