PubMed

HLA-DQ-regulated T-cell responses to islet cell autoantigens insulin and GAD65.

Tree TI, Duinkerken G, Willemen S, de Vries RR, Roep BO.

Diabetes. 2004 Jul;53(7):1692-9.PMID: 15220192 [PubMed - indexed for MEDLINE]Related articlesFree article

T cell response pattern to glutamic acid decarboxylase 65 (GAD65) peptides of newly diagnosed type 1 diabetic patients sharing susceptible HLA haplotypes.

Rharbaoui F, Mayer A, Granier C, Bouanani M, Thivolet C, Pau B, Orgiazzi J, Madec AM.

Clin Exp Immunol. 1999 Jul;117(1):30-7.PMID: 10403912 [PubMed - indexed for MEDLINE]Related articlesFree article

Processing and presentation of the islet autoantigen GAD by vascular endothelial cells promotes transmigration of autoreactive T-cells.

Greening JE, Tree TI, Kotowicz KT, van Halteren AG, Roep BO, Klein NJ, Peakman M.

Diabetes. 2003 Mar;52(3):717-25.PMID: 12606513 [PubMed - indexed for MEDLINE]Related articlesFree article

Progression to insulin-requiring diabetes in seronegative prediabetic subjects: the role of two HLA-DQ high-risk haplotypes.

Pietropaolo M, Becker DJ, LaPorte RE, Dorman JS, Riboni S, Rudert WA, Mazumdar S, Trucco M.

Diabetologia. 2002 Jan;45(1):66-76.PMID: 11845225 [PubMed - indexed for MEDLINE]Related articles

Identification of peptides from autoantigens GAD65 and IA-2 that bind to HLA class II molecules predisposing to or protecting from type 1 diabetes.

Harfouch-Hammoud E, Walk T, Otto H, Jung G, Bach JF, van Endert PM, Caillat-Zucman S.

Diabetes. 1999 Oct;48(10):1937-47.PMID: 10512357 [PubMed - indexed for MEDLINE]Related articlesFree article

Autoreactive T cell responses in insulin-dependent (Type 1) diabetes mellitus. Report of the first international workshop for standardization of T cell assays.

Roep BO, Atkinson MA, van Endert PM, Gottlieb PA, Wilson SB, Sachs JA.

J Autoimmun. 1999 Sep;13(2):267-82.PMID: 10479395 [PubMed - indexed for MEDLINE]Related articles

Activation of CD8+ T lymphocytes in insulin-dependent diabetes mellitus.

Togun RA, Resetkova E, Kawai K, Enomoto T, Volpé R.

Clin Immunol Immunopathol. 1997 Mar;82(3):243-9.PMID: 9073547 [PubMed - indexed for MEDLINE]Related articles

Major DQ8-restricted T-cell epitopes for human GAD65 mapped using human CD4, DQA1*0301, DQB1*0302 transgenic IA(null) NOD mice.

Liu J, Purdy LE, Rabinovitch S, Jevnikar AM, Elliott JF.

Diabetes. 1999 Mar;48(3):469-77.PMID: 10078545 [PubMed - indexed for MEDLINE]Related articlesFree article

Glutamic acid decarboxylase T lymphocyte responses associated with susceptibility or resistance to type I diabetes: analysis in disease discordant human twins, non-obese diabetic mice and HLA-DQ transgenic mice.

Boyton RJ, Lohmann T, Londei M, Kalbacher H, Halder T, Frater AJ, Douek DC, Leslie DG, Flavell RA, Altmann DM.

Int Immunol. 1998 Dec;10(12):1765-76.PMID: 9885897 [PubMed - indexed for MEDLINE]Related articlesFree article

T cell proliferative responses to glutamic acid decarboxylase-65 in IDDM are negatively associated with HLA DR3/4.

Worsaae A, Hejnaes K, Moody A, Ludvigsson J, Pociot F, Lorenzen T, Dyrberg T.

Autoimmunity. 1995;22(3):183-9.PMID: 8734572 [PubMed - indexed for MEDLINE]Related articles

HLA-DR binding analysis of peptides from islet antigens in IDDM.

Geluk A, van Meijgaarden KE, Schloot NC, Drijfhout JW, Ottenhoff TH, Roep BO.

Diabetes. 1998 Oct;47(10):1594-601.PMID: 9753297 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of preparations of GAD65, proinsulin, and the islet tyrosine phosphatase IA-2 for use in detection of autoreactive T-cells in type 1 diabetes: report of phase II of the Second International Immunology of Diabetes Society Workshop for Standardization of T-cell assays in type 1 diabetes.

Peakman M, Tree TI, Endl J, van Endert P, Atkinson MA, Roep BO; Second International Immunology of Diabetes Society Workshop for Standardization ot T-cell Assays in Type 1 Diabetes.

Diabetes. 2001 Aug;50(8):1749-54.PMID: 11473034 [PubMed - indexed for MEDLINE]Related articlesFree article

Relation between cellular and humoral immunity to islet cell antigens in type 1 diabetes.

Hummel M, Durinovic-Bello I, Ziegler AG.

J Autoimmun. 1996 Jun;9(3):427-30.PMID: 8816982 [PubMed - indexed for MEDLINE]Related articles

T-cell reactivity to GAD65 peptide sequences shared with coxsackie virus protein in recent-onset IDDM, post-onset IDDM patients and control subjects.

Schloot NC, Roep BO, Wegmann DR, Yu L, Wang TB, Eisenbarth GS.

Diabetologia. 1997 Mar;40(3):332-8.PMID: 9084973 [PubMed - indexed for MEDLINE]Related articles

Evidence for in vivo primed and expanded autoreactive T cells as a specific feature of patients with type 1 diabetes.

Monti P, Scirpoli M, Rigamonti A, Mayr A, Jaeger A, Bonfanti R, Chiumello G, Ziegler AG, Bonifacio E.

J Immunol. 2007 Nov 1;179(9):5785-92.PMID: 17947651 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 1 diabetes-predisposing MHC alleles influence the selection of glutamic acid decarboxylase (GAD) 65-specific T cells in a transgenic model.

Abraham RS, Wen L, Marietta EV, David CS.

J Immunol. 2001 Jan 15;166(2):1370-9.PMID: 11145722 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of a human T cell line reactive to a 52 kDa islet protein.

Sobel DO, Fleisher T, Karounos DG.

J Autoimmun. 1997 Aug;10(4):387-94.PMID: 9237802 [PubMed - indexed for MEDLINE]Related articles

Genetic control of immune response and disease susceptibility by the HLA-DQ gene.

Nishimura Y, Kamikawaji N, Fujisawa K, Yoshizumi H, Yasunami M, Kimura A, Sasazuki T.

Res Immunol. 1991 Jun-Aug;142(5-6):459-66. Review.PMID: 1684444 [PubMed - indexed for MEDLINE]Related articles

T cell responses to enterovirus antigens and to beta-cell autoantigens in unaffected children positive for IDDM-associated autoantibodies.

Juhela S, Hyöty H, Hinkkanen A, Elliott JF, Roivainen M, Kulmala P, Rahko J, Knip M, Ilonen J.

J Autoimmun. 1999 Jun;12(4):269-78. Erratum in: J Autoimmun. 2006 May;26(3):223. Elliott, J [corrected to Elliott, JF]. PMID: 10330298 [PubMed - indexed for MEDLINE]Related articles

Autoimmunity and genetics contribute to the risk of insulin-dependent diabetes mellitus in families: islet cell antibodies and HLA DQ heterodimers.

Lipton RB, Kocova M, LaPorte RE, Dorman JS, Orchard TJ, Riley WJ, Drash AL, Becker DJ, Trucco M.

Am J Epidemiol. 1992 Sep 1;136(5):503-12.PMID: 1442714 [PubMed - indexed for MEDLINE]Related articles