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    Results: 1 to 20 of 131

    1.

    Lilly lecture 2003: the struggle for mastery in insulin action: from triumvirate to republic.

    Accili D.

    Diabetes. 2004 Jul;53(7):1633-42.PMID: 15220184 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Impaired glucose tolerance in mice with a targeted impairment of insulin action in muscle and adipose tissue.

    Lauro D, Kido Y, Castle AL, Zarnowski MJ, Hayashi H, Ebina Y, Accili D.

    Nat Genet. 1998 Nov;20(3):294-8.PMID: 9806552 [PubMed - indexed for MEDLINE]Related articles

    3.

    Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

    Nakae J, Biggs WH 3rd, Kitamura T, Cavenee WK, Wright CV, Arden KC, Accili D.

    Nat Genet. 2002 Oct;32(2):245-53. Epub 2002 Sep 3.PMID: 12219087 [PubMed - indexed for MEDLINE]Related articles

    4.

    [Relative importance of insulin actin in insulin's target tissues]

    Sasaoka T, Kobayashi M.

    Nippon Rinsho. 2000 Feb;58(2):291-6. Review. Japanese. PMID: 10707547 [PubMed - indexed for MEDLINE]Related articles

    5.

    [Insulin signaling and pathophysiology of type 2 diabetes mellitus]

    Ogawa W, Kasuga M.

    Nippon Rinsho. 2006 Jul;64(7):1381-9. Review. Japanese. PMID: 16838661 [PubMed - indexed for MEDLINE]Related articles

    6.

    Nonobese, insulin-deficient Ins2Akita mice develop type 2 diabetes phenotypes including insulin resistance and cardiac remodeling.

    Hong EG, Jung DY, Ko HJ, Zhang Z, Ma Z, Jun JY, Kim JH, Sumner AD, Vary TC, Gardner TW, Bronson SK, Kim JK.

    Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1687-96. Epub 2007 Oct 2.PMID: 17911348 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes.

    Fernández AM, Kim JK, Yakar S, Dupont J, Hernandez-Sanchez C, Castle AL, Filmore J, Shulman GI, Le Roith D.

    Genes Dev. 2001 Aug 1;15(15):1926-34.PMID: 11485987 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Mouse models of insulin resistance.

    Hribal ML, Oriente F, Accili D.

    Am J Physiol Endocrinol Metab. 2002 May;282(5):E977-81. Review.PMID: 11934661 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Identifying the links between obesity, insulin resistance and beta-cell function: potential role of adipocyte-derived cytokines in the pathogenesis of type 2 diabetes.

    Greenberg AS, McDaniel ML.

    Eur J Clin Invest. 2002 Jun;32 Suppl 3:24-34. Review.PMID: 12028372 [PubMed - indexed for MEDLINE]Related articles

    10.

    Knockout models are useful tools to dissect the pathophysiology and genetics of insulin resistance.

    Mauvais-Jarvis F, Kulkarni RN, Kahn CR.

    Clin Endocrinol (Oxf). 2002 Jul;57(1):1-9. Review.PMID: 12100063 [PubMed - indexed for MEDLINE]Related articles

    11.

    Gene expression in humans with diabetes and prediabetes: what have we learned about diabetes pathophysiology?

    Patti ME.

    Curr Opin Clin Nutr Metab Care. 2004 Jul;7(4):383-90. Review.PMID: 15192439 [PubMed - indexed for MEDLINE]Related articles

    12.

    In vivo mutagenesis of the insulin receptor.

    Okamoto H, Accili D.

    J Biol Chem. 2003 Aug 1;278(31):28359-62. Epub 2003 Jun 4. Review.PMID: 12788928 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus.

    Heilbronn L, Smith SR, Ravussin E.

    Int J Obes Relat Metab Disord. 2004 Dec;28 Suppl 4:S12-21. Review.PMID: 15592481 [PubMed - indexed for MEDLINE]Related articles

    14.

    Insulin signal transduction in human skeletal muscle: identifying the defects in Type II diabetes.

    Björnholm M, Zierath JR.

    Biochem Soc Trans. 2005 Apr;33(Pt 2):354-7. Review.PMID: 15787605 [PubMed - indexed for MEDLINE]Related articles

    15.

    Beta-cell dysfunction and insulin resistance in type 2 diabetes: role of metabolic and genetic abnormalities.

    LeRoith D.

    Am J Med. 2002 Oct 28;113 Suppl 6A:3S-11S. Review.PMID: 12431757 [PubMed - indexed for MEDLINE]Related articles

    16.

    Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM.

    DeFronzo RA.

    Diabetes. 1988 Jun;37(6):667-87. Review. No abstract available. PMID: 3289989 [PubMed - indexed for MEDLINE]Related articles

    17.

    Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance.

    Chibalin AV, Leng Y, Vieira E, Krook A, Björnholm M, Long YC, Kotova O, Zhong Z, Sakane F, Steiler T, Nylén C, Wang J, Laakso M, Topham MK, Gilbert M, Wallberg-Henriksson H, Zierath JR.

    Cell. 2008 Feb 8;132(3):375-86.PMID: 18267070 [PubMed - indexed for MEDLINE]Related articles

    18.

    Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus.

    Kubota N, Terauchi Y, Tobe K, Yano W, Suzuki R, Ueki K, Takamoto I, Satoh H, Maki T, Kubota T, Moroi M, Okada-Iwabu M, Ezaki O, Nagai R, Ueta Y, Kadowaki T, Noda T.

    J Clin Invest. 2004 Oct;114(7):917-27.PMID: 15467830 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility.

    Keller MP, Choi Y, Wang P, Davis DB, Rabaglia ME, Oler AT, Stapleton DS, Argmann C, Schueler KL, Edwards S, Steinberg HA, Chaibub Neto E, Kleinhanz R, Turner S, Hellerstein MK, Schadt EE, Yandell BS, Kendziorski C, Attie AD.

    Genome Res. 2008 May;18(5):706-16. Epub 2008 Mar 17.PMID: 18347327 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Energy restriction prevents the development of type 2 diabetes in Zucker diabetic fatty rats: coordinated patterns of gene expression for energy metabolism in insulin-sensitive tissues and pancreatic islets determined by oligonucleotide microarray analysis.

    Colombo M, Kruhoeffer M, Gregersen S, Agger A, Jeppesen P, Oerntoft T, Hermansen K.

    Metabolism. 2006 Jan;55(1):43-52.PMID: 16324918 [PubMed - indexed for MEDLINE]Related articles

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