PubMed

Hypothesis: Induced angiogenesis after surgery in premenopausal node-positive breast cancer patients is a major underlying reason why adjuvant chemotherapy works particularly well for those patients.

Retsky M, Bonadonna G, Demicheli R, Folkman J, Hrushesky W, Valagussa P.

Breast Cancer Res. 2004;6(4):R372-4. Epub 2004 May 14.PMID: 15217504 [PubMed - indexed for MEDLINE]Related articlesFree article

Premenopausal status accelerates relapse in node positive breast cancer: hypothesis links angiogenesis, screening controversy.

Retsky M, Demicheli R, Hrushesky W.

Breast Cancer Res Treat. 2001 Feb;65(3):217-24.PMID: 11336243 [PubMed - indexed for MEDLINE]Related articles

Overview of resistance to systemic therapy in patients with breast cancer.

Gonzalez-Angulo AM, Morales-Vasquez F, Hortobagyi GN.

Adv Exp Med Biol. 2007;608:1-22. Review.PMID: 17993229 [PubMed - indexed for MEDLINE]Related articles

Prognostic importance of tumor angiogenesis in breast carcinoma with adjuvant chemotherapy.

Gunel N, Akcali Z, Coskun U, Akyol G, Yamac D, Yenidünya S.

Pathol Res Pract. 2002;198(1):7-12.PMID: 11866215 [PubMed - indexed for MEDLINE]Related articles

T1-T2 breast cancer with four or more positive axillary lymph nodes: adjuvant locoregional radiotherapy with high-dose or standard-dose chemotherapy. Results of an observational study.

Perrucci E, Aristei C, De Angelis V, Anselmo P, Mascioni F, Gori S, Frattegiani A, Latini P.

Tumori. 2004 Jul-Aug;90(4):379-86.PMID: 15510979 [PubMed - indexed for MEDLINE]Related articles

Addition of granulocyte-colony stimulating factor (G-CSF) may further increase chemosensitive state in premenopausal node-positive breast cancer patients with induced angiogenesis after surgery.

Altundag K, Altundag O, Gunduz M.

Breast Cancer Res. 2004 Jun 15;6(4):E14. Print 2004. No abstract available. PMID: 15217491 [PubMed - indexed for MEDLINE]Related articlesFree article

Randomized trial of adjuvant ovarian suppression in 926 premenopausal patients with early breast cancer treated with adjuvant chemotherapy.

Arriagada R, Lê MG, Spielmann M, Mauriac L, Bonneterre J, Namer M, Delozier T, Hill C, Tursz T.

Ann Oncol. 2005 Mar;16(3):389-96. Epub 2005 Jan 27.PMID: 15677625 [PubMed - indexed for MEDLINE]Related articlesFree article

Micrometastases or isolated tumor cells and the outcome of breast cancer.

de Boer M, van Deurzen CH, van Dijck JA, Borm GF, van Diest PJ, Adang EM, Nortier JW, Rutgers EJ, Seynaeve C, Menke-Pluymers MB, Bult P, Tjan-Heijnen VC.

N Engl J Med. 2009 Aug 13;361(7):653-63.PMID: 19675329 [PubMed - indexed for MEDLINE]Related articlesFree article

Prognostic implications of isolated tumor cells and micrometastases in sentinel nodes of patients with invasive breast cancer: 10-year analysis of patients enrolled in the prospective East Carolina University/Anne Arundel Medical Center Sentinel Node Multicenter Study.

Reed J, Rosman M, Verbanac KM, Mannie A, Cheng Z, Tafra L.

J Am Coll Surg. 2009 Mar;208(3):333-40. Epub 2008 Dec 25.PMID: 19317993 [PubMed - indexed for MEDLINE]Related articles

Enhanced surgery-induced angiogenesis among premenopausal women might partially explain excess breast cancer mortality of blacks compared to whites: an hypothesis.

Retsky MW, Demicheli R, Gukas ID, Hrushesky WJ.

Int J Surg. 2007 Oct;5(5):300-4. Epub 2007 Jan 8.PMID: 17933694 [PubMed - indexed for MEDLINE]Related articles

Is chemotherapy necessary for premenopausal women with lower-risk node-positive, endocrine responsive breast cancer? 10-year update of International Breast Cancer Study Group Trial 11-93.

Thürlimann B, Price KN, Gelber RD, Holmberg SB, Crivellari D, Colleoni M, Collins J, Forbes JF, Castiglione-Gertsch M, Coates AS, Goldhirsch A.

Breast Cancer Res Treat. 2009 Jan;113(1):137-44. Epub 2008 Feb 8.PMID: 18259856 [PubMed - indexed for MEDLINE]Related articles

Does surgery induce angiogenesis in breast cancer? Indirect evidence from relapse pattern and mammography paradox.

Retsky M, Demicheli R, Hrushesky WJ.

Int J Surg. 2005;3(3):179-87. Epub 2005 Sep 12.PMID: 17462282 [PubMed]Related articles

Hazard of recurrence and adjuvant treatment effects over time in lymph node-negative breast cancer.

Dignam JJ, Dukic V, Anderson SJ, Mamounas EP, Wickerham DL, Wolmark N.

Breast Cancer Res Treat. 2009 Aug;116(3):595-602. Epub 2008 Oct 2.PMID: 18830816 [PubMed - indexed for MEDLINE]Related articles

Postoperative loco-regional radiation therapy for breast cancer patients with four or more involved lymph nodes or extracapsular extension.

Evron E, Barzily L, Rakowsky E, Ben-Baruch N, Sulkes J, Rizel S, Fenig E.

Isr Med Assoc J. 2005 Jul;7(7):439-42.PMID: 16011059 [PubMed - indexed for MEDLINE]Related articlesFree article

Locoregional radiation therapy in patients with high-risk breast cancer receiving adjuvant chemotherapy: 20-year results of the British Columbia randomized trial.

Ragaz J, Olivotto IA, Spinelli JJ, Phillips N, Jackson SM, Wilson KS, Knowling MA, Coppin CM, Weir L, Gelmon K, Le N, Durand R, Coldman AJ, Manji M.

J Natl Cancer Inst. 2005 Jan 19;97(2):116-26.PMID: 15657341 [PubMed - indexed for MEDLINE]Related articlesFree article

LHRH agonists for adjuvant therapy of early breast cancer in premenopausal women.

Sharma R, Hamilton A, Beith J.

Cochrane Database Syst Rev. 2008 Oct 8;(4):CD004562. Review. Update in: Cochrane Database Syst Rev. 2009;(4):CD004562. PMID: 18843661 [PubMed - indexed for MEDLINE]Related articles

Prognostic significance of bcl-2 expression in stage III breast cancer patients who had received doxorubicin and cyclophosphamide followed by paclitaxel as adjuvant chemotherapy.

Lee KH, Im SA, Oh DY, Lee SH, Chie EK, Han W, Kim DW, Kim TY, Park IA, Noh DY, Heo DS, Ha SW, Bang YJ.

BMC Cancer. 2007 Apr 12;7:63.PMID: 17430582 [PubMed - indexed for MEDLINE]Related articlesFree article

American Joint Committee on Cancer tumor-node-metastasis stage after neoadjuvant chemotherapy and breast cancer outcome.

Carey LA, Metzger R, Dees EC, Collichio F, Sartor CI, Ollila DW, Klauber-DeMore N, Halle J, Sawyer L, Moore DT, Graham ML.

J Natl Cancer Inst. 2005 Aug 3;97(15):1137-42.PMID: 16077072 [PubMed - indexed for MEDLINE]Related articlesFree article

Lymphovascular invasion is associated with reduced locoregional control and survival in women with node-negative breast cancer treated with mastectomy and systemic therapy.

Truong PT, Yong CM, Abnousi F, Lee J, Kader HA, Hayashi A, Olivotto IA.

J Am Coll Surg. 2005 Jun;200(6):912-21.PMID: 15922205 [PubMed - indexed for MEDLINE]Related articles

Anemia is a significant prognostic factor in local relapse-free survival of premenopausal primary breast cancer patients receiving adjuvant cyclophosphamide/methotrexate/5-fluorouracil chemotherapy.

Dubsky P, Sevelda P, Jakesz R, Hausmaninger H, Samonigg H, Seifert M, Denison U, Mlineritsch B, Steger G, Kwasny W, Stöger H, Bartsch R, Stierer M, Taucher S, Fridrik M, Schippinger W, Greil R, Pötter R, Gnant M; Austrian Breast and Colorectal Cancer Study Group.

Clin Cancer Res. 2008 Apr 1;14(7):2082-7.PMID: 18381948 [PubMed - indexed for MEDLINE]Related articlesFree article